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Related papers: Associative learning in biochemical networks

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Traditional drug discovery programs are being transformed by the advent of machine learning methods. Among these, Generative AI methods (GM) have gained attention due to their ability to design new molecules and enhance specific properties…

Learning and the ability to learn are important factors in development and evolutionary processes [1]. Depending on the level, the complexity of learning can strongly vary. While associative learning can explain simple learning behaviour…

Neurons and Cognition · Quantitative Biology 2007-05-23 Reimer Kuehn , Ion-Olimpiu Stamatescu

Codistillation has been proposed as a mechanism to share knowledge among concurrently trained models by encouraging them to represent the same function through an auxiliary loss. This contrasts with the more commonly used fully-synchronous…

Machine Learning · Computer Science 2021-07-27 Shagun Sodhani , Olivier Delalleau , Mahmoud Assran , Koustuv Sinha , Nicolas Ballas , Michael Rabbat

We analyze a class of chemical reaction networks under mass-action kinetics and involving multiple time-scales, whose deterministic and stochastic models display qualitative differences. The networks are inspired by gene-regulatory…

Molecular Networks · Quantitative Biology 2018-01-30 Tomislav Plesa , Radek Erban , Hans G. Othmer

A recurrent neural network model of phonological pattern learning is proposed. The model is a relatively simple neural network with one recurrent layer, and displays biases in learning that mimic observed biases in human learning.…

Computation and Language · Computer Science 2024-05-31 Amanda Doucette

This paper extends the reinforcement learning ideas into the multi-agents system, which is far more complicated than the previously studied single-agent system. We studied two different multi-agents systems. One is the fully-connected…

Artificial Intelligence · Computer Science 2015-05-18 Zhipeng Wang , Mingbo Cai

Connectionist models such as neural networks suffer from catastrophic forgetting. In this work, we study this problem from the perspective of information theory and define forgetting as the increase of description lengths of previous data…

Machine Learning · Computer Science 2020-06-29 Xu He , Min Lin

In this letter, we present an original demonstration of an associative learning neural network inspired by the famous Pavlov's dogs experiment. A single nanoparticle organic memory field effect transistor (NOMFET) is used to implement each…

Neurons and Cognition · Quantitative Biology 2013-02-19 O. Bichler , W. Zhao , F. Alibart , S. Pleutin , S. Lenfant , D. Vuillaume , C. Gamrat

The current biochemical information processing systems behave in a predetermined manner because all features are defined during the design phase. To make such unconventional computing systems reusable and programmable for biomedical…

Molecular Networks · Quantitative Biology 2014-07-15 Peter Banda , Christof Teuscher

This paper presents a neural network model (associative memory model) for memory and recall of images. In this model, only a single neuron can memorize multi-images and when that neuron is activated, it is possible to recall all the…

Neural and Evolutionary Computing · Computer Science 2025-10-09 Hiroshi Inazawa

We describe a mechanism for biological learning and adaptation based on two simple principles: (I) Neuronal activity propagates only through the network's strongest synaptic connections (extremal dynamics), and (II) The strengths of active…

Disordered Systems and Neural Networks · Physics 2009-10-31 Per Bak , Dante R Chialvo

In this work, we introduce Adapt & Align, a method for continual learning of neural networks by aligning latent representations in generative models. Neural Networks suffer from abrupt loss in performance when retrained with additional…

Machine Learning · Computer Science 2023-12-22 Kamil Deja , Bartosz Cywiński , Jan Rybarczyk , Tomasz Trzciński

Coupled learning is a contrastive scheme for tuning the properties of individual elements within a network in order to achieve desired functionality of the system. It takes advantage of physics both to learn using local rules and to…

Soft Condensed Matter · Physics 2024-07-09 Lauren E. Altman , Menachem Stern , Andrea J. Liu , Douglas J. Durian

This paper argues that continual learning methods can benefit by splitting the capacity of the learner across multiple models. We use statistical learning theory and experimental analysis to show how multiple tasks can interact with each…

Machine Learning · Computer Science 2024-05-07 Rahul Ramesh , Pratik Chaudhari

A range of generative machine learning models for the design of novel molecules and materials have been proposed in recent years. Models that can generate three-dimensional structures are particularly suitable for quantum chemistry…

In this work we show how a network inspired by a coarse-grained description of actomyosin cytoskeleton can learn - in a contrastive learning framework - from environmental perturbations if it is endowed with mechanosensitive proteins and…

Modeling of turbulent combustion system requires modeling the underlying chemistry and the turbulent flow. Solving both systems simultaneously is computationally prohibitive. Instead, given the difference in scales at which the two…

Machine Learning · Computer Science 2022-02-22 Amol Salunkhe , Dwyer Deighan , Paul DesJardin , Varun Chandola

Discovery of the molecular candidates for applications in drug targets, biomolecular systems, catalysts, photovoltaics, organic electronics, and batteries, necessitates development of machine learning algorithms capable of rapid exploration…

Machine Learning · Computer Science 2023-12-12 Ayana Ghosh , Sergei V. Kalinin , Maxim A. Ziatdinov

We consider a neural network with adapting synapses whose dynamics can be analitically computed. The model is made of $N$ neurons and each of them is connected to $K$ input neurons chosen at random in the network. The synapses are…

Disordered Systems and Neural Networks · Physics 2009-10-30 G. Lattanzi , G. Nardulli , G. Pasquariello , S. Stramaglia

Evolution produces complex and structured networks of interacting components in chemical, biological, and social systems. We describe a simple mathematical model for the evolution of an idealized chemical system to study how a network of…

Adaptation and Self-Organizing Systems · Physics 2014-03-05 Sanjay Jain , Sandeep Krishna