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To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

In biological systems, molecular-scale forces and motions are pivotal for enabling processes like motility, shape change, and replication. These forces and motions are organized, amplified, and transmitted across macroscopic scales by…

Living systems are capable of locomotion, reconfiguration, and replication. To perform these tasks, cells spatiotemporally coordinate the interactions of force-generating, "active" molecules that create and manipulate non-equilibrium…

Soft Condensed Matter · Physics 2019-08-28 Tyler D. Ross , Heun Jin Lee , Zijie Qu , Rachel A. Banks , Rob Phillips , Matt Thomson

A hitherto unexploited characteristic feature of emerging iontronic devices for information processing is the intrinsic mobility of the medium (water) of dissolved ions in aqueous electrolytes, which therefore not only respond to voltage…

Soft Condensed Matter · Physics 2024-04-24 A. Barnaveli , T. M. Kamsma , W. Q. Boon , R. van Roij

Circulating tumor cells (CTCs) have crucial roles in the spread of tumors during metastasis. A decisive step is the extravasation of CTCs from the blood stream or lymph system, which depends on the ability of cells to attach to vessel…

Microelectronic morphogenesis is the creation and maintenance of complex functional structures by microelectronic information within shape-changing materials. Only recently has in-built information technology begun to be used to reshape…

Robotics · Computer Science 2024-05-24 John S. McCaskill , Daniil Karnaushenko , Minshen Zhu , Oliver G. Schmidt

The concept of a magnetic bipolar transistor (MBT) is introduced. The transistor has at least one magnetic region (emitter, base, or collector) characterized by spin-splitting of the carrier bands. In addition, nonequilibrium (source) spin…

Condensed Matter · Physics 2007-05-23 Jaroslav Fabian , Igor Zutic , S. Das Sarma

To obtain precisely controllable, robust as well as reproduceable memristor for efficient neuromorphic computing still very challenging. Molecular tailoring aims at obtaining the much more flexibly tuning plasticity has recently generated…

Mesoscale and Nanoscale Physics · Physics 2017-04-06 Zhiyong Wang , Laiyuan Wang , Masaru Nagai , Linghai Xie , Haifeng Ling , Qi Li , Ying Zhu , Tengfei Li , Mingdong Yi , Naien Shi , Wei Huang

Length-regulation of microtubules (MTs) is essential for many cellular processes. Molecular motors like kinesin 8, which move along MTs and also act as depolymerases, are known as key players in MT dynamics. However, the regulatory…

Subcellular Processes · Quantitative Biology 2012-10-18 Anna Melbinger , Louis Reese , Erwin Frey

We focus on potential mechanisms for `energy-loss-free' transport along the cell microtubules, which could be considered as realizations of Fr\"ohlich's ideas on the role of solitons for superconductivity and/or biological matter. In…

Quantum Physics · Physics 2007-05-23 N. E. Mavromatos , D. V. Nanopoulos

Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the…

Subcellular Processes · Quantitative Biology 2018-06-13 Bryan Kaye , Olivia Stiehl , Peter J. Foster , Michael J. Shelley , Daniel J. Needleman , Sebastian Fürthauer

Biological cells, by definition, are the basic units which contain the fundamental molecules of life of which all living things are composed. Understanding how they function and differentiating cells from one another therefore is of…

Signal Processing · Electrical Eng. & Systems 2021-01-07 Hassan Raji , Muhammad Tayyab , Jianye Sui , Seyed Reza Mahmoodi , Mehdi Javanmard

In this paper, we review the different memristive threshold logic (MTL) circuits that are inspired from the synaptic action of flow of neurotransmitters in the biological brain. Brain like generalisation ability and area minimisation of…

Emerging Technologies · Computer Science 2016-04-26 Akshay Kumar Maan , Deepthi Anirudhan Jayadevi , Alex Pappachen James

Microtubules and motor proteins are building blocks of self-organized subcellular biological structures such as the mitotic spindle and the centrosomal microtubule array. These same ingredients can form new "bioactive" liquid-crystalline…

Soft Condensed Matter · Physics 2015-01-29 Tong Gao , Robert Blackwell , Matthew A. Glaser , M. D. Betterton , Michael J. Shelley

Magnetic tunnel junctions (MTJs) play a crucial role in spintronic applications, particularly data storage and sensors. Especially as a non-volatile memory, MTJs have received substantial attention due to its CMOS compatibility, low power…

The cytoskeleton is a model active matter system that controls diverse cellular processes from division to motility. While both active actomyosin dynamics and actin-microtubule interactions are key to the cytoskeleton's versatility and…

The advent of memristors and resistive switching has transformed solid state physics, enabling advanced applications such as neuromorphic computing. Inspired by these developments, we introduce the concept of Mem-emitters, devices that…

Mimicking the collective excitatory and inhibitory behaviors of biological neurons remains a critical challenge in the development of neuromorphic computing systems that rival the complexity and performance of the human brain. Volatile…

The microtubule cytoskeleton is responsible for sustained, long-range intracellular transport of mRNAs, proteins, and organelles in neurons. Neuronal microtubules must be stable enough to ensure reliable transport, but they also undergo…

Dynamical Systems · Mathematics 2024-03-05 Anna C Nelson , Melissa M Rolls , Maria-Veronica Ciocanel , Scott A McKinley

We study electrical properties of Taxol-stabilised microtubule (MT) ensembles in a droplet of water. We demonstrate that the MT droplets act as electrical switches. Also, a stimulation of a MT droplet with a positive fast impulse causes…

Emerging Technologies · Computer Science 2021-05-12 Alessandro Chiolerio , Thomas C. Draper , Richard Mayne , Andrew Adamatzky