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Evolutionary events such as incomplete lineage sorting and lateral gene transfer constitute major problems for inferring species trees from gene trees, as they can sometimes lead to gene trees which conflict with the underlying species…

Populations and Evolution · Quantitative Biology 2013-04-23 Andreas Sand , Mike Steel

In this paper we compute the limit distributions of the numbers of hairpin-loops, interior-loops and bulges in k-noncrossing RNA structures. The latter are coarse grained RNA structures allowing for cross-serial interactions, subject to the…

Combinatorics · Mathematics 2009-12-03 Markus E. Nebel , Christian M. Reidys , Rita R. Wang

Chromosomal rearrangements, which shuffle DNA throughout the genome, are an important source of divergence across taxa. Using a paired-end read approach with Illumina sequence data for archaic humans, I identify changes in genome structure…

Genomics · Quantitative Biology 2015-10-07 Rebekah L. Rogers

This work illustrates potentials for recognition within {\em ad hoc} sensor networks if their nodes possess individual inter-related biologically inspired genetic codes. The work takes ideas from natural immune systems protecting organisms…

Cryptography and Security · Computer Science 2009-12-31 Reinert Korsnes , Knut Ovsthus

Thru-hole epitaxy has recently been reported to be able to grow readily detachable domains crystallographically aligned with the underlying substrate over 2D mask material transferred onto a substrate. [Jang \textit{et al.}, \textit{Adv.…

Materials Science · Physics 2024-02-12 Youngjun Lee , Seungjun Lee , Jaewu Choi , Chinkyo Kim , Young-Kyun Kwon

Determining the mechanism by which transfer RNAs (tRNAs) rapidly and precisely transit through the ribosomal A, P and E sites during translation remains a major goal in the study of protein synthesis. Here, we report the real-time dynamics…

Biomolecules · Quantitative Biology 2012-08-27 Jingyi Fei , Jonathan E. Bronson , Jake M. Hofman , Rathi L. Srinivas , Chris H. Wiggins , Ruben L. Gonzalez,

The inference of gene regulatory networks (GRNs) is a foundational stride towards deciphering the fundamentals of complex biological systems. Inferring a possible regulatory link between two genes can be formulated as a link prediction…

Machine Learning · Computer Science 2025-04-25 Binon Teji , Swarup Roy

When many fundamental strings are stacked together, they puff up into D-branes. BIons and giant gravitons are the examples of such D-brane configurations that arise from coincident strings. We propose and demonstrate analogous transitions…

High Energy Physics - Theory · Physics 2009-04-17 Takuya Okuda

In the work the process of the energy transfer in the cell microtubules is simulated. A system of tryptophans connected by Coulomb dipole-dipole interaction is discussed as the energy carriers. The work models the conditions under which the…

Biological Physics · Physics 2023-03-08 Sergey Ehduardovich Shirmovsky

Accurate RNA structure modeling remains difficult because RNA backbones are highly flexible, non-canonical interactions are prevalent, and experimentally determined 3D structures are comparatively scarce. We introduce \emph{RiboSphere}, a…

Machine Learning · Computer Science 2026-03-23 Zhou Zhang , Hanqun Cao , Cheng Tan , Fang Wu , Pheng Ann Heng , Tianfan Fu

Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes. In this paper we analyse…

Analysis of PDEs · Mathematics 2014-04-03 Mark Chaplain , Mariya Ptashnyk , Marc Sturrock

Results of experiments probing the structure of the pomeron at hadron colliders and at HERA are reviewed. By renormalizing the pomeron flux factor in diffraction dissociation as dictated by unitarity, a picture emerges from the data in…

High Energy Physics - Phenomenology · Physics 2007-05-23 Konstantin Goulianos

Transcriptional regulation of gene expression is one of the main processes that affect cell diversification from a single set of genes. Regulatory proteins often interact with DNA regions located distally from the transcription start sites…

Genomics · Quantitative Biology 2014-04-30 Sofie Demeyer , Tom Michoel

The transport of macromolecules, such as DNA, through the cytoskeleton is critical to wide-ranging cellular processes from cytoplasmic streaming to transcription. The rigidity and steric hindrances imparted by the network of filaments…

Cytoskeletal crowding plays a key role in the diffusion of DNA molecules through the cell, acting as a barrier to effective intracellular transport and conformational stability required for such processes as transfection, viral infection,…

Transition metal dichalcogenide heterobilayers offer attractive opportunities to realize lattices of interacting bosons with several degrees of freedom. Such heterobilayers can feature moir\'e patterns that modulate their electronic band…

Mesoscale and Nanoscale Physics · Physics 2021-08-16 Mauro Brotons-Gisbert , Hyeonjun Baek , Aidan Campbell , Kenji Watanabe , Takashi Taniguchi , Brian D. Gerardot

The formation mechanism of operons remains controversial despite the proposal of many models. Although acquisition of genes from other species, horizontal gene transfer, is considered to occur, definitive concrete cases have been…

Populations and Evolution · Quantitative Biology 2007-05-23 Keiichi Homma , Satoshi Fukuchi , Yoji Nakamura , Takashi Gojobori , Ken Nishikawa

The phage $\lambda$ infection of an \textit{E. coli} cell has become a paradigm for understanding the molecular processes involved in gene expression and cell signaling. This system provides an example of a genetic switch, as cells with…

Biological Physics · Physics 2012-04-10 Nathan Borggren

Gene expression-based heterogeneity analysis has been extensively conducted. In recent studies, it has been shown that network-based analysis, which takes a system perspective and accommodates the interconnections among genes, can be more…

Methodology · Statistics 2023-08-09 Rong Li , Qingzhao Zhang , Shuangge Ma

The problem of RNA secondary structure design (also called inverse folding) is the following: given a target secondary structure, one aims to create a sequence that folds into, or is compatible with, a given structure. In several practical…

Quantitative Methods · Quantitative Biology 2013-08-02 Yu Zhou , Yann Ponty , Stéphane Vialette , Jérôme Waldispühl , Yi Zhang , Alain Denise
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