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Recombination is introduced into Eigen's theory of quasispecies evolution. Comparing numerical simulations of the rate equations in the non-recombining and recombining cases show that recombination has a strong effect on the error threshold…

Populations and Evolution · Quantitative Biology 2007-05-23 Martin Nilsson Jacobi , Mats Nordahl

The adoption of agroecological practices will be crucial to address the challenges of climate change and biodiversity loss. Such practices favor the cultivation of plants in complex mixtures with layouts differing from the monoculture…

Populations and Evolution · Quantitative Biology 2024-09-26 Julian Talbot , Pascal Viot , David Colliaux

Background: Speciation corresponds to the progressive establishment of reproductive barriers between groups of individuals derived from an ancestral stock. Since Darwin did not believe that reproductive barriers could be selected for, he…

Populations and Evolution · Quantitative Biology 2011-12-12 Etienne Joly

We analyze and reinterpret experimental evidence from the literature to argue for an ability of tumor cells to self-regulate their aneuploidy rate. We conjecture that this ability is mediated by a diversification factor that exploits…

Cell Behavior · Quantitative Biology 2013-03-27 Domenico Napoletani , Michele Signore , Daniele C. Struppa

The origin of altruistic behavior, i.e. the behavior that is useful for a population or a species but goes at the expense of an altruistic individual, has long been a challenge for students of evolutionary biology. The populations with…

Populations and Evolution · Quantitative Biology 2010-02-24 T. Kulich , J. Flegr

Many examples of cooperation exist in biology. In chemical systems however, which can sometimes be quite complex, we do not appear to observe intricate cooperative interactions. A key question for the origin of life, is then how can…

Populations and Evolution · Quantitative Biology 2018-02-23 Omer Markovitch , Olaf Witkowski , Nathaniel Virgo

We study the convenience of a nonlocal dispersal strategy in a reaction-diffusion system with a fractional Laplacian operator. We show that there are circumstances - namely, a precise condition on the distribution of the resource - under…

Analysis of PDEs · Mathematics 2016-03-30 Annalisa Massaccesi , Enrico Valdinoci

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Understanding cell fate selection remains a central challenge in developmental biology. We present a class of simple yet biologically-motivated mathematical models for cell differentiation that generically generate oscillations and hence…

Dynamical Systems · Mathematics 2021-10-08 Saeed Farjami , Karen Camargo Sosa , Jonathan H. P. Dawes , Robert N. Kelsh , Andrea Rocco

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

We are interested in the long time behavior of a two-type density-dependent biological population conditioned to non-extinction, in both cases of competition or weak cooperation between the two species. This population is described by a…

Probability · Mathematics 2008-11-04 Patrick Cattiaux , Sylvie Méléard

During development, spatio-temporal patterns ranging from checkerboard to engulfing occur with precise proportions of the respective cell fates. Key developmental regulators are intracellular transcriptional interactions and intercellular…

Biological Physics · Physics 2022-11-15 Simon Schardt , Sabine C. Fischer

We compare and contrast the long-time dynamical properties of two individual-based models of biological coevolution. Selection occurs via multispecies, stochastic population dynamics with reproduction probabilities that depend nonlinearly…

Populations and Evolution · Quantitative Biology 2011-11-10 Per Arne Rikvold

Social insect colonies can be seen as a distinct form of biological organization because they function as superorganisms. Understanding how natural selection acts on the emergence and maintenance of these colonies remains a major question…

Populations and Evolution · Quantitative Biology 2014-07-02 Feng Fu , Sarah D. Kocher , Martin A. Nowak

Can prelife proceed without cell division? A recently proposed mechanism suggests that transient compartmentalization could have preceded cell division in prebiotic scenarios. Here, we study transient compartmentalization dynamics in the…

Populations and Evolution · Quantitative Biology 2019-12-17 Alex Blokhuis , Philippe Nghe , Luca Peliti , David Lacoste

The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…

Cell Behavior · Quantitative Biology 2016-06-22 Benjamin Pfeuty , Kunihiko Kaneko

Feature interaction selection is a fundamental problem in commercial recommender systems. Most approaches equally enumerate all features and interactions by the same pre-defined operation under expert guidance. Their recommendation is…

Artificial Intelligence · Computer Science 2024-05-30 Runlong Yu , Qixiang Shao , Qi Liu , Huan Liu , Enhong Chen

In biology and ecology, individuals or communities of individuals living in unpredictable environments often alternate between different evolutionary strategies to spread and reduce risks. Such behavior is commonly referred to as…

Populations and Evolution · Quantitative Biology 2015-03-11 Jorge Hidalgo , Simone Pigolotti , Miguel A. Munoz

In cellular reprogramming, almost all epigenetic memories of differentiated cells are erased by the overexpression of few genes, regaining pluripotency, potentiality for differentiation. Considering the interplay between oscillatory gene…

Biological Physics · Physics 2021-09-14 Yuuki Matsushita , Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

The amplification cycle of many replicators (natural or artificial) involves the usage of a host compartment, inside of which the replicator express phenotypic compounds necessary to carry out its genetic replication. For example, viruses…

Populations and Evolution · Quantitative Biology 2019-07-03 Anton S. Zadorin , Yannick Rondelez