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To simplify mathematical models of disease spread, we often assume equal contact rates among hosts, but real-world scenarios differ. Network-based frameworks help capture these complexities and structural variations in actual systems. We…

Dynamical Systems · Mathematics 2024-07-03 Saswata Das , Mohammad Hossein Samaei , Caterina Scoglio

Numerous experimental studies have demonstrated that the microenvironment is a key regulator influencing the proliferative and migrative potentials of species. Spatial and temporal disturbances lead to adverse and hazardous…

Populations and Evolution · Quantitative Biology 2015-10-07 Venkata. S. K. Manem , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

The contact structure of the population shapes the progression of epidemics. Nonetheless, the joint evolution of individual behavioral adaptations and disease dynamics on networks remains poorly understood. We use a…

Physics and Society · Physics 2025-08-27 Baltazar Espinoza , Jimmy Calvo-Monge , Fabio Sanchez , Simon A. Levin , Madhav Marathe

In this paper we study intra-host viral adaptation by antigenic cooperation - a mechanism of immune escape that serves as an alternative to the standard mechanism of escape by continuous genomic diversification and allows to explain a…

Populations and Evolution · Quantitative Biology 2023-04-07 Leonid Bunimovich , Athulya Ram , Pavel Skums

The network of interactions in complex systems, strongly influences their resilience, the system capability to resist to external perturbations or structural damages and to promptly recover thereafter. The phenomenon manifests itself in…

Physics and Society · Physics 2018-04-11 Malbor Asllani , Timoteo Carletti

The propagation of model epidemics on a small-world network under the action of immunization is studied. Although the connectivity in this kind of networks is rather uniform, a vaccination strategy focused on the best connected individuals…

Statistical Mechanics · Physics 2009-11-07 Damian H. Zanette , Marcelo Kuperman

We consider the spread of infectious disease through contact networks of Configuration Model type. We assume that the disease spreads through contacts and infected individuals recover into an immune state. We discuss a number of existing…

Populations and Evolution · Quantitative Biology 2014-03-11 Joel C Miller , Istvan Z Kiss

Most of zoonoses are multi-host parasites with multiple transmission routes that are usually investigated separately despite their potential interplay. As a unifying framework for modelling parasite spread through different paths of…

Quantitative Methods · Quantitative Biology 2017-06-19 Massimo Stella , Sanja Selakovic , Alberto Antonioni , Cecilia S. Andreazzi

Disease awareness in infection dynamics can be modeled with adaptive contact networks whose rewiring rules reflect the attempt by susceptibles to avoid infectious contacts. Simulations of this type of models show an active phase with…

Adaptation and Self-Organizing Systems · Physics 2012-12-06 Stefan Wieland , Tomas Aquino , Ana Nunes

We investigate the spread of an infection or other malfunction of cascading nature when a system component can recover only if it remains reachable from a functioning central component. We consider the susceptible-infected-susceptible…

Physics and Society · Physics 2016-04-27 L. Böttcher , O. Woolley-Meza , E. Goles , D. Helbing , H. J. Herrmann

We study the spreading of an infection within an SIS epidemiological model on a network. Susceptible agents are given the opportunity of breaking their links with infected agents. Broken links are either permanently removed or reconnected…

Populations and Evolution · Quantitative Biology 2007-11-07 Damian H. Zanette , Sebastian Risau Gusman

The long-term evolution of epidemic processes depends crucially on the structure of contact networks. As empirical evidence indicates that human populations exhibit strong community organization, we investigate here how such mesoscopic…

Physics and Society · Physics 2016-11-09 T. Jesan , Chandrashekar Kuyyamudi , Sitabhra Sinha

We study the dynamics of epidemic and reaction-diffusion processes in metapopulation models with heterogeneous connectivity pattern. In SIR-like processes, along with the standard local epidemic threshold, the system exhibits a global…

Physics and Society · Physics 2009-11-13 Vittoria Colizza , Alessandro Vespignani

Infectious diseases are practically represented by models with multiple states and complex transition rules corresponding to, for example, birth, death, infection, recovery, disease progression, and quarantine. In addition, networks…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

We study the spreading of an infection within an SIS epidemiological model on a network. Susceptible agents are given the opportunity of breaking their links with infected agents, and reconnecting those links with the rest of the…

Physics and Society · Physics 2007-07-11 Damian H. Zanette

We model and calculate the fraction of infected population necessary to reach herd immunity, taking into account the heterogeneity in infectiousness and susceptibility, as well as the correlation between those two parameters. We show that…

Populations and Evolution · Quantitative Biology 2021-01-19 Yaron Oz , Ittai Rubinstein , Muli Safra

Spatial extent is a complicating factor in mathematical biology. The possibility that an action at point A cannot immediately affect what happens at point B creates the opportunity for spatial nonuniformity. This nonuniformity must change…

Cellular Automata and Lattice Gases · Physics 2014-01-03 Blake C. Stacey , Andreas Gros , Yaneer Bar-Yam

In this paper, we focus on susceptible-infected-susceptible dynamics on metapopulation networks, where nodes represent subpopulations, and where agents diffuse and interact. Recent studies suggest that heterogeneous network structure…

Physics and Society · Physics 2015-06-11 Taro Takaguchi , Renaud Lambiotte

Many real world networks are characterized by adaptive changes in their topology depending on the dynamic state of their nodes. Here we study epidemic dynamics in an adaptive network, where susceptibles are able to avoid contact with…

Populations and Evolution · Quantitative Biology 2007-05-23 Thilo Gross , Carlos Dommar D'Lima , Bernd Blasius

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at…

Physics and Society · Physics 2016-10-20 Xiao-Long Peng , Xin-Jian Xu , Michael Small , Xinchu Fu , Zhen Jin