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Finite mixture models are fitted to spherical data. Kent distributions are used for the components of the mixture because they allow considerable flexibility. Previous work on such mixtures has used an approximate maximum likelihood…

Statistics Theory · Mathematics 2021-04-28 Kanti V. Mardia , Stuart Barber , Philippa M. Burdett , John T. Kent , Thomas Hamelryck

In this work we introduce two code families, which we call the heavy hexagon code and heavy square code. Both code families are implemented by assigning physical data and ancilla qubits to both vertices and edges of low degree graphs. Such…

Overlapping genes exist in all domains of life and are much more abundant than expected at their first discovery in the late 1970s. Assuming that the reference gene is read in frame +0, an overlapping gene can be encoded in two reading…

Genomics · Quantitative Biology 2017-01-20 Sophie Lebre , Olivier Gascuel

Correlation of gene histories in the human genome determines the patterns of genetic variation (haplotype structure) and is crucial to understanding genetic factors in common diseases. We derive closed analytical expressions for the…

Genomics · Quantitative Biology 2009-11-10 A. Eriksson , B. Mehlig

The sensitivity of the native states of protein-like heteropolymers to mutations modelled as perturbations in the interaction potential between amino acids is studied. The stability threshold against mutations is shown to be zero for random…

Soft Condensed Matter · Physics 2009-10-30 Michele Vendruscolo , Amos Maritan , Jayanth R. Banavar

New analyses of the organization of the genetic code system together with their relation to the two classes of aminoacyl-tRNA synthetases are reported in this work. A closer inspection revealed how the enzymes and the 20 amino acids of the…

Biomolecules · Quantitative Biology 2007-05-23 Chi Ming Yang

Why is the genetic code the way it is? The most successful theory states that the codon assignments minimise the effects of errors arising in primordial living systems. Here a transversion is reported that leaves invariant degeneracy in the…

Biological Physics · Physics 2007-05-23 Jean-Luc Jestin

We derive the amino acid assignment to one codon representation (typical 64-dimensional irreducible representation) of the basic classical Lie superalgebra osp(5|2) from biochemical arguments. We motivate the approach of mathematical…

General Physics · Physics 2012-02-03 Sebastian Sachse , Christian Roeder

The helical coil is ubiquitous in biological and natural systems and often it is the basic form that leads to complex structures. This paper considers the question of its dimensionality in biological information as the helical coil goes…

Biological Physics · Physics 2024-07-04 Subhash Kak

The distribution of bases spacing in human genome was investigated. An analysis of the frequency of occurrence in the human genome of different sequence lengths flanked by one type of nucleotide was carried out showing that the distribution…

Other Quantitative Biology · Quantitative Biology 2019-04-18 Andrzej Z. Górski , Monika Piwowar

Topological color codes are among the stabilizer codes with remarkable properties from quantum information perspective. In this paper we construct a four-valent lattice, the so called ruby lattice, governed by a 2-body Hamiltonian. In a…

Strongly Correlated Electrons · Physics 2015-05-13 M. Kargarian , H. Bombin , M. A. Martin-Delgado

Hydrogen bonding is modeled in terms of virtual exchange of protons between water molecules. A simple lattice model is analyzed, using ideas and techniques from the theory of correlated electrons in metals. Reasonable parameters reproduce…

Soft Condensed Matter · Physics 2009-11-11 Daniel W. Hone , P. A. Pincus

Coding information is the main source of heterogeneity (non-randomness) in the sequences of bacterial genomes. This information can be naturally modeled by analysing cluster structures in the "in-phase" triplet distributions of relatively…

Genomics · Quantitative Biology 2011-11-09 A. N. Gorban , T. G. Popova , A. Yu. Zinovyev

The nature of the quantitative distribution of the 64 DNA codons in the human genome has been an issue of debate for over a decade. Some groups have proposed that the quantitative distribution of the DNA codons ordered as a rank-frequency…

Genomics · Quantitative Biology 2015-01-06 Bohdan B. Khomtchouk

A two-dimensional grid with dots is called a \emph{configuration with distinct differences} if any two lines which connect two dots are distinct either in their length or in their slope. These configurations are known to have many…

Combinatorics · Mathematics 2009-10-08 Simon R. Blackburn , Tuvi Etzion , Keith M. Martin , Maura B. Paterson

In nature the three-dimensional structure of a protein is encoded in the corresponding gene. In this paper we describe a new method for encoding the three-dimensional structure of a protein into a binary sequence. The feature of the method…

Combinatorics · Mathematics 2007-05-23 Naoto Morikawa

The hydrogen bond is a fundamental ingredient to stabilize the DNA and RNA macromolecules. The main contribution of this work is to describe quantitatively this interaction as a consequence of the quantum confinement of the hydrogen. The…

Chemical Physics · Physics 2015-02-10 da Silva dos Santos , Elso Drigo Filho , Regina Maria Ricotta

A codon table is a useful tool for mapping codons to amino acids as they have been assigned by nature. It has become a scientific icon because of the way it embodies our understanding of this natural process and the way it immediately…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Mark White

We begin with the extraordinary observation that the length distribution of 80 million proteins in UniProt, the Universal Protein Resource, measured in amino acids, is qualitatively identical to the length distribution of large collections…

Other Quantitative Biology · Quantitative Biology 2017-09-13 Les Hatton , Gregory Warr

Bicyclic codes are a generalization of the one dimensional (1D) cyclic codes to two dimensions (2D). Similar to the 1D case, in some cases, 2D cyclic codes can also be constructed to guarantee a specified minimum distance. Many aspects of…

Quantum Physics · Physics 2024-04-08 Sankara Sai Chaithanya Rayudu , Pradeep Kiran Sarvepalli