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Related papers: Multiple sequence alignment based on set covers

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Progressive methods offer efficient and reasonably good solutions to the multiple sequence alignment problem. However, resulting alignments are biased by guide-trees, especially for relatively distant sequences. We propose MSARC, a new…

Quantitative Methods · Quantitative Biology 2013-07-31 Michał Modzelewski , Norbert Dojer

Multiple sequence alignment is a key process in today's biology, and finding a relevant alignment of several sequences is much more challenging than just optimizing some improbable evaluation functions. Our approach for addressing multiple…

Quantitative Methods · Quantitative Biology 2008-12-18 Frédéric Guinand , Yoann Pigné

Advances in bio-technology have made available massive amounts of functional, structural and genomic data for many biological sequences. This increased availability of heterogeneous biological data has resulted in biological applications…

Computational Engineering, Finance, and Science · Computer Science 2013-02-26 Srikrishnan Divakaran , Arpit Mithal , Namit Jain

The way for performing multiple sequence alignment is based on the criterion of the maximum scored information content computed from a weight matrix, but it is possible to have two or more alignments to have the same highest score leading…

Quantitative Methods · Quantitative Biology 2014-03-03 Jian-Jun Shu , Kian Yan Yong , Weng Kong Chan

Multiple sequence alignment is a basic procedure in molecular biology, and it is often treated as being essentially a solved computational problem. However, this is not so, and here I review the evidence for this claim, and outline the…

Populations and Evolution · Quantitative Biology 2018-08-24 David A. Morrison

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

Various methods have been developed to analyze the association between organisms and their genomic sequences. Among them, sequence alignment is the most frequently used for comparative analysis of biological genomes. However, the…

Quantitative Methods · Quantitative Biology 2020-10-27 Yong Joon Song , Dong Jin Ji , Hye In Seo , Gyu Bum Han , Dong Ho Cho

This paper describes a new alignment algorithm for sequences that can be used for determination of deletions and substitutions. It provides several solutions out of which the best one can be chosen on the basis of minimization of gaps or…

Information Theory · Computer Science 2012-11-01 Sandeep Hosangadi , Subhash Kak

An extension to a recently introduced architecture of clique-based neural networks is presented. This extension makes it possible to store sequences with high efficiency. To obtain this property, network connections are provided with…

Neural and Evolutionary Computing · Computer Science 2014-09-02 Xiaoran Jiang , Vincent Gripon , Claude Berrou , Michael Rabbat

Multiple Sequences Alignment (MSA) of biological sequences is a fundamental problem in computational biology due to its critical significance in wide ranging applications including haplotype reconstruction, sequence homology, phylogenetic…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-05-13 Fahad Saeed , Ashfaq Khokhar

Recently, several authors have advocated the use of rule learning algorithms to model multi-label data, as rules are interpretable and can be comprehended, analyzed, or qualitatively evaluated by domain experts. Many rule learning…

Machine Learning · Computer Science 2020-12-09 Michael Rapp , Eneldo Loza Mencía , Johannes Fürnkranz

An overview of current multiple alignment systems to date are described.The useful algorithms, the procedures adopted and their limitations are presented.We also present the quality of the alignments obtained and in which cases(kind of…

Data Structures and Algorithms · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Pyro-Align is a multiple alignment program specifically designed for pyrosequencing reads of huge number. Multiple sequence alignment is shown to be NP-hard and heuristics are designed for approximate solutions. Multiple sequence alignment…

Data Structures and Algorithms · Computer Science 2009-01-20 Fahad Saeed

We propose some new method of constructing configurations, which consists in consecutive inscribing copies of one underlying configuration. A uniform characterization of the obtained class and the one introduced in our paper untitled…

Combinatorics · Mathematics 2012-03-13 Krzysztof Petelczyc , Krzysztof Prażmowski

We address the text-to-text generation problem of sentence-level paraphrasing -- a phenomenon distinct from and more difficult than word- or phrase-level paraphrasing. Our approach applies multiple-sequence alignment to sentences gathered…

Computation and Language · Computer Science 2007-05-23 Regina Barzilay , Lillian Lee

A novel approach to protein multiple sequence alignment is discussed: substantially this method counterparts with substitution matrix based methods (like Blosum or PAM based methods), and implies a more deterministic approach to…

Other Quantitative Biology · Quantitative Biology 2007-06-07 Stefano Marino

Transformer-based language models such as BERT have achieved the state-of-the-art performance on various NLP tasks, but are computationally prohibitive. A recent line of works use various heuristics to successively shorten sequence length…

Computation and Language · Computer Science 2022-03-29 Xin Huang , Ashish Khetan , Rene Bidart , Zohar Karnin

Multi-label text classification (MLTC) aims to assign multiple labels to each sample in the dataset. The labels usually have internal correlations. However, traditional methods tend to ignore the correlations between labels. In order to…

Computation and Language · Computer Science 2018-09-11 Pengcheng Yang , Shuming Ma , Yi Zhang , Junyang Lin , Qi Su , Xu Sun

We consider set covering problems where the underlying set system satisfies a particular replacement property w.r.t. a given partial order on the elements: Whenever a set is in the set system then a set stemming from it via the replacement…

Discrete Mathematics · Computer Science 2015-03-17 Friedrich Eisenbrand , Naonori Kakimura , Thomas Rothvoß , Laura Sanità

The article proposes a heuristic approximation approach to the bin packing problem under multiple objectives. In addition to the traditional objective of minimizing the number of bins, the heterogeneousness of the elements in each bin is…

Artificial Intelligence · Computer Science 2008-09-05 Martin Josef Geiger
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