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Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase. Using Monte Carlo…

Biomolecules · Quantitative Biology 2009-05-04 Hu Chen , Yanhui Liu , Zhen Zhou , Lin Hu , Zhong-Can Ou-Yang , Jie Yan

We present results on tagged particle diffusion in a meso-scale lattice model for sheared amorphous material in athermal quasi-static conditions. We find a short time diffusive regime and a long time diffusive regime whose diffusion…

Soft Condensed Matter · Physics 2018-10-10 Botond Tyukodi , Craig E Maloney , Damien Vandembroucq

Recent advances in high-resolution experimental methods have highlighted the significance of cell signal pathway crosstalk and localised signalling activity in the development and disease of numerous biological systems. The investigation of…

Dynamical Systems · Mathematics 2022-09-19 Joshua W. Moore , Trevor C. Dale , Thomas E. Woolley

Mass-conserving reaction-diffusion systems with bistable nonlinearity are useful models for studying cell polarity formation, which is a key process in cell division and differentiation. We rigorously show the existence and stability of…

Analysis of PDEs · Mathematics 2025-05-23 Masataka Kuwamura , Takashi Teramoto , Hideo Ikeda

A simple, discrete, parametric model is proposed to describe conditional (correlated) deposition of particles on a surface and formation of a connecting (percolating) cluster. The surface changes spontaneously its properties (phase…

Statistical Mechanics · Physics 2007-05-23 Ana Proykova , Boris Karadjov

From the perspective of physical properties, the cell membrane is an exotic two-dimensional material that has a dual nature: it exhibits characteristics of fluids, i.e., lipid molecules show lateral diffusion, while also demonstrating…

Soft Condensed Matter · Physics 2024-04-19 Vikash Pandey , Dhrubaditya Mitra

The study of the interactions of living adherent cells with mechanically stable (visco)elastic materials enables understanding and exploiting physiological phenomena mediated by cell-extracellular communication. However, insight on the…

How epithelial cells coordinate their polarity to form functional tissues is an open question in cell biology. Here, we characterize a unique type of polarity found in liver tissue, nematic cell polarity, which is different from vectorial…

Bacteria commonly inhabit porous environments such as host tissues, soil, and marine sediments, where complex geometries constrain and redirect their motion. Although bacterial motility has been studied in porous media, the roles of cell…

Soft Condensed Matter · Physics 2025-12-22 David Gao , Zeyuan Wang , Mihika Jain , Arnold J. T. M. Mathijssen , Ran Tao

We construct a coarse-grained effective two-dimensional (2d) hydrodynamic theory as a theoretical model for a coupled system of a fluid membrane and a thin layer of a polar active fluid in its ordered state that is anchored to the membrane.…

Soft Condensed Matter · Physics 2012-11-15 Niladri Sarkar , Abhik Basu

Multiple scattering of polarised electromagnetic waves in diffusive media is investigated by means of radiative transfer theory. The method becomes exact in several situations of interest, such as a thick-slab experiment (slab thickness L…

Condensed Matter · Physics 2009-10-28 E. Amic , J. M. Luck , Th. M. Nieuwenhuizen

Prokaryotes do not make use of a nucleus membrane to segregate their genetic material from the cytoplasm, so that their nucleoid is potentially free to explore the whole volume of the cell. Nonetheless, high resolution images of bacteria…

Biological Physics · Physics 2019-10-31 Marc Joyeux

Protein aggregation on the plasma membrane (PM) is of critical importance to many cellular processes such as cell adhesion, endocytosis, fibrillar conformation, and vesicle transport. Lateral diffusion of protein aggregates or clusters on…

Subcellular Processes · Quantitative Biology 2019-08-15 L. M. Stolerman , M. Getz , S. G. Llewellyn Smith , M. Holst , P. Rangamani

In this work, we investigate the dynamics of a non-local model describing spontaneous cell polarisation. It consists in a drift-diffusion equation set in the half-space, with the coupling involving the trace value on the boundary. We…

Analysis of PDEs · Mathematics 2011-05-24 Vincent Calvez , Rhoda Hawkins , Nicolas Meunier , Raphael Voituriez

Growing living cultures of Escherichia coli bacteria were investigated using real-time in situ rheology and rheo-imaging measurements. In the early stages of growth (lag phase), and when subjected to a constant stationary shear, the…

Biological Physics · Physics 2016-12-21 R. Portela , P. Patrício , P. L. Almeida , R. G. Sobral , J. M. Franco , C. R. Leal

The growing interest in the non-equilibrium assembly of colloidal particles in active liquids is driven by the motivation to create novel structures endowed with tunable properties unattainable within the confines of equilibrium systems.…

Soft Condensed Matter · Physics 2024-03-06 Pragya Kushwaha , Sayan Maity , Anjaly S. Menon , Raghunath Chelakkot , Vijayakumar Chikkadi

Particles with ligand-receptor contacts bind and unbind fluctuating "legs" to surfaces, whose fluctuations cause the particle to diffuse. Quantifying the diffusion of such "nanoscale caterpillars" is a challenge, since binding events often…

Soft Condensed Matter · Physics 2022-03-21 Sophie Marbach , Jeana Aojie Zheng , Miranda Holmes-Cerfon

The key of tip growth in eukaryotes is the polarized distribution on plasma membrane of a particle named ROP1. This distribution is the result of a positive feedback loop, whose mechanism can be described by a Differential Equation…

Methodology · Statistics 2016-05-03 Zhen Xiao , Nicolas Brunel , Zhenbiao Yang , Xinping Cui

Using techniques of the theory of semigroups of linear operators we study the question of approximating solutions to equations governing diffusion in thin layers separated by a semi-permeable membrane. We show that as thickness of the…

Analysis of PDEs · Mathematics 2019-08-08 Adam Bobrowski

We consider the densities of clusters, at the percolation point of a two-dimensional system, which are anchored in various ways to an edge. These quantities are calculated by use of conformal field theory and computer simulations. We find…

Disordered Systems and Neural Networks · Physics 2009-11-11 P. Kleban , J. J. H. Simmons , R. M. Ziff