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A new method (`explosive immunization' (EI)) is proposed for immunization and targeted destruction of networks. It combines the explosive percolation (EP) paradigm with the idea of maintaining a fragmented distribution of clusters. The…

Physics and Society · Physics 2016-11-16 Pau Clusella , Peter Grassberger , Francisco J. Perez-Reche , Antonio Politi

We consider optimal attacks or immunization schemes on different models of random graphs. We derive bounds for the minimum number of nodes needed to be removed from a network such that all remaining components are fragments of negligible…

Physics and Society · Physics 2019-12-10 Nicole Balashov , Reuven Cohen , Avieli Haber , Michael Krivelevich , Simi Haber

Empirical data on contacts between individuals in social contexts play an important role in providing information for models describing human behavior and how epidemics spread in populations. Here, we analyze data on face-to-face contacts…

How to allocate vaccines over heterogeneous individuals is one of the important policy decisions in pandemic times. This paper develops a procedure to estimate an individualized vaccine allocation policy under limited supply, exploiting…

Econometrics · Economics 2021-10-25 Toru Kitagawa , Guanyi Wang

Network intervention problems often benefit from selecting a highly-connected node to perform interventions using these nodes, e.g. immunization. However, in many network contexts, the structure of network connections is unknown, leading to…

Social and Information Networks · Computer Science 2021-05-20 Vineet Kumar , David Krackhardt , Scott Feld

We propose a targeted intervention protocol where recovery is restricted to individuals that have the least number of infected neighbours. Our recovery strategy is highly efficient on any kind of network, since epidemic outbreaks are…

Physics and Society · Physics 2017-10-31 Lucas Böttcher , José S. Andrade , Hans J. Herrmann

In this work, we address a multicoupled dynamics on complex networks with tunable structural segregation. Specifically, we work on a networked epidemic spreading under a vaccination campaign with agents in favor and against the vaccine. Our…

Physics and Society · Physics 2021-09-15 Marcelo A. Pires , Andre L. Oestereich , Nuno Crokidakis , Sílvio M. Duarte Queirós

The limited availability of COVID-19 vaccines has prompted extensive research on optimal vaccination strategies. Previous studies have considered various non-pharmaceutical interventions, vaccine efficacy, and distribution strategies. In…

Populations and Evolution · Quantitative Biology 2025-02-27 Iker Atienza-Diez , Gabriel Rodriguez-Maroto , Saúl Ares , Susanna Manrubia

Considering the global pandemic of coronavirus disease 2019 (COVID-19), around the world several vaccines are being developed. Till now, these vaccines are the most effective way to reduce the high burden on the global health…

Physics and Society · Physics 2023-02-22 Dibyajyoti Mallick , Aniruddha Ray , Ankita Das , Sayantari Ghosh

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

Seasonal influenza is a significant public health concern in the United States and globally. While influenza vaccines are the single most effective intervention to reduce influenza morbidity and mortality, there is considerable debate…

Populations and Evolution · Quantitative Biology 2015-01-07 Eric Mooring , Shweta Bansal

Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a…

Physics and Society · Physics 2019-09-04 Liqun Lu , Yanfeng Ouyang

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Information regarding vaccines from sources such as health services, media, and social networks can significantly shape vaccination decisions. In particular, the dissemination of negative information can contribute to vaccine hesitancy,…

Social and Information Networks · Computer Science 2024-07-04 Sarah Alahmadi , Rebecca Hoyle , Michael Head , Markus Brede

When trying to maximize the adoption of a behavior in a population connected by a social network, it is common to strategize about where in the network to seed the behavior, often with an element of randomness. Selecting seeds uniformly at…

Methodology · Statistics 2020-06-22 Alex Chin , Dean Eckles , Johan Ugander

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

Populations and Evolution · Quantitative Biology 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin

Effective vaccine prioritization is critical for epidemic control, yet real outbreaks exhibit memory effects that inflate state space and make long-term prediction and optimization challenging. As a result, many strategies are tuned to…

Biological Physics · Physics 2025-11-11 Mi Feng , Liang Tian , Changsong Zhou
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