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Adding edges between layers of interconnected networks is an important way to optimize the spreading dynamics. While previous studies mostly focus on the case of adding a single edge, the theoretical optimal strategy for adding multiple…

Physics and Society · Physics 2019-10-09 Liming Pan , Wei Wang , Shimin Cai , Tao Zhou

We develop semiparametric methods for estimating subgroup-specific relative vaccine efficacy against multiple viral strains in a partially vaccinated population. Focusing on observational case-only studies, we address informative…

Methodology · Statistics 2025-03-12 Lars van der Laan , Peter B. Gilbert

The paper is an introduction to the concept of vaccine efficacy and its practical applications. We provide illustrative examples aimed at a wider audience.

Populations and Evolution · Quantitative Biology 2021-07-27 Sorana Froda , Fabrice Larribe

We find that different geographical structures of networks lead to varied percolation thresholds, although these networks may have similar abstract topological structures. Thus, the strategies for enhancing robustness and immunization of a…

Physics and Society · Physics 2009-09-29 Liang Huang , Lei Yang , Kongqing Yang

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

Optimization and Control · Mathematics 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

In some social and biological networks, the majority of nodes belong to multiple communities. It has recently been shown that a number of the algorithms that are designed to detect overlapping communities do not perform well in such highly…

Physics and Society · Physics 2015-05-28 Conrad Lee , Fergal Reid , Aaron McDaid , Neil Hurley

We consider the distributed optimization problem, where a group of agents work together to optimize a common objective by communicating with neighboring agents and performing local computations. For a given algorithm, we use tools from…

Optimization and Control · Mathematics 2020-09-11 Bryan Van Scoy , Laurent Lessard

We consider a susceptible, infected, and recovered infectious disease model which incorporates a vaccination rate. In particular, we study the problem of choosing the vaccination rate in order to reduce the number of infected individuals to…

Analysis of PDEs · Mathematics 2021-08-30 Ryan Hynd , Dennis Ikpe , Terrance Pendleton

In this paper, we study the control of the traffic-driven epidemic spreading by immunization strategy. We consider the random, degree-based and betweeness-based immunization strategies, respectively. It is found that the betweeness-based…

Physics and Society · Physics 2018-02-14 Han-Xin Yang , Bing-Hong Wang

How to prevent the spread of human diseases is a great challenge for the scientific community and so far there are many studies in which immunization strategies have been developed. However, these kind of strategies usually do not consider…

Physics and Society · Physics 2018-08-22 M. A. Di Muro , L. G. Alvarez-Zuzek , S. Havlin , L. A. Braunstein

In many non-cooperative settings, agents often possess useful information that provide an advantage over their opponent(s), but acting on such information too frequently can lead to detection. I develop a simple framework to analyze such a…

General Economics · Economics 2024-12-17 Xiaoming Wang

The spontaneous behavioral changes of the agents during an epidemic can have significant effects on the delay and the prevalence of its spread. In this work, we study a social distancing game among the agents of a population, who determine…

Physics and Society · Physics 2020-07-13 A. -R. Lagos , I. Kordonis , G. P. Papavassilopoulos

Vaccination is essential for the management of infectious diseases, many of which continue to pose devastating public health and economic challenges across the world. However, many vaccines are imperfect having only a partial protective…

Populations and Evolution · Quantitative Biology 2022-08-04 Hetsron L. Nyandjo-Bamen , Jean Marie Ntaganda , Aurelien Tellier , Olivier Menoukeu-Pamen

We address the problem of allocating limited resources in a network under persistent yet statistically unknown adversarial attacks. Each node in the network may be degraded, but not fully disabled, depending on its available defensive…

Data Structures and Algorithms · Computer Science 2025-07-01 Mansoor Davoodi , Setareh Maghsudi

Information dissemination intricately intertwines with the dynamics of infectious diseases in the contemporary interconnected world. Recognizing the critical role of public awareness, individual vaccination choices appear to be an essential…

Physics and Society · Physics 2024-10-30 Viney Kumar , Chris T Bauch , Samit Bhattacharyya

Complex networks are at the core of an intense research activity. However, in most cases, intricate and costly measurement procedures are needed to explore their structure. In some cases, these measurements rely on link queries: given two…

Networking and Internet Architecture · Computer Science 2009-04-22 Fabien Tarissan , Matthieu Latapy , Christophe Prieur

Estimating vaccination uptake is an integral part of ensuring public health. It was recently shown that vaccination uptake can be estimated automatically from web data, instead of slowly collected clinical records or population surveys. All…

Information Retrieval · Computer Science 2017-02-24 Niels Dalum Hansen , Kåre Mølbak , Ingemar J. Cox , Christina Lioma

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

We consider the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-metapopulation model (including SIS, SIR, SEIR,. . .), when the loss function is given by the effective reproduction number Re, which is defined…

Optimization and Control · Mathematics 2021-10-26 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt
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