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Viral kinetics have been extensively studied in the past through the use of spatially well-mixed ordinary differential equations describing the time evolution of the diseased state. However, emerging spatial structures such as localized…

Cell Behavior · Quantitative Biology 2024-04-02 Catherine Beauchemin

This paper performs the utilization of cellular automata computational analysis as the dynamic model of spatial epidemiology. Here, explored elementary aspects of cellular automata and its application in analyzing contagious disease, in…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Hokky Situngkir

A cellular automaton (CA)-based modeling approach to simulate wildfire spread, emphasizing its strengths in capturing complex fire dynamics and its integration with geographic information systems (GIS). The model introduces an enhanced…

Cellular Automata and Lattice Gases · Physics 2024-03-15 Rohit Ghosh , Jishnu Adhikary , Rezki Chemlal

We present a lattice gas cellular automaton (LGCA) to study spatial and temporal dynamics of an epidemic of SIR (susceptible-infected-removed) type. The automaton is fully discrete, i.e. space, time and number of individuals are discrete…

Cellular Automata and Lattice Gases · Physics 2023-12-18 Henryk Fuks , Anna T. Lawniczak

The results of Kermack-McKendrick SIR model are planned to be reproduced by cellular automata (CA) lattice model. The CA algorithms are proposed to study the model of epidemic, systematically. The basic goal is to capture the effects of…

Populations and Evolution · Quantitative Biology 2022-08-30 Agniva Datta , Muktish Acharyya

In this paper we use the cellular automaton (CA) approach to model one-dimensional binary diffusion in solids. Employing a very simple state change rule we define an asynchronous CA model and take its continuum limit to obtain the governing…

Computational Physics · Physics 2019-11-20 Helena Ribera , Brian Wetton , Timothy Myers

The evolutionary dynamics of human Influenza A virus presents a challenging theoretical problem. An extremely high mutation rate allows the virus to escape, at each epidemic season, the host immune protection elicited by previous…

Populations and Evolution · Quantitative Biology 2016-11-30 Lorenzo Taggi , Francesca Colaiori , Vittorio Loreto , Francesca Tria

Currently, the world has been facing the brunt of a pandemic due to a disease called COVID-19 for the last 2 years. To study the spread of such infectious diseases it is important to not only understand their temporal evolution but also the…

Biological Physics · Physics 2023-08-01 Sourav Chowdhury , Suparna Roychowdhury , Indranath Chaudhuri

We study differential equations describing the spread of influenza A virus infection based on a mathematical model. We look for surface trajectories of the dynamical system in hand and their asymptotic behaviour.

Geometric Topology · Mathematics 2021-11-29 Boldizsar Kalmar

The steady state properties of the mean density population of infected cells in a viral spread is simulated by a general forest fire like cellular automaton model with two distinct populations of cells ( permissive and resistant ones) and…

adap-org · Physics 2008-02-03 G. Camelo-Neto , S. Coutinho

In this paper we present ACEMod, an agent-based modelling framework for studying influenza epidemics in Australia. The simulator is designed to analyse the spatiotemporal spread of contagion and influenza spatial synchrony across the…

Multiagent Systems · Computer Science 2018-06-08 Oliver M. Cliff , Nathan Harding , Mahendra Piraveenan , E. Yagmur Erten , Manoj Gambhir , Mikhail Prokopenko

The role of direct cell-to-cell spread in viral infections - where virions spread between host and susceptible cells without needing to be secreted into the extracellular environment - has come to be understood as essential to the dynamics…

Quantitative Methods · Quantitative Biology 2024-05-21 Thomas Williams , James M. McCaw , James Osborne

The stochastic discrete space-time model of an immune response on tumor spreading in a two-dimensional square lattice has been developed. The immunity-tumor interactions are described at the cellular level and then transferred into the…

comp-gas · Physics 2007-05-23 Margarita Voitikova

Global mobility flow data are at the heart of spatial epidemiological models used to predict infectious disease behavior but this wealth of data on human mobility has been largely neglected by reconstructions of pathogen evolutionary…

Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…

Applications · Statistics 2019-08-20 Md Mahsin , Rob Deardon , Patrick Brown

A major contribution to the onset and development of autoimmune disease is known to come from infections. An important practical problem is identifying the precise mechanism by which the breakdown of immune tolerance as a result of immune…

Quantitative Methods · Quantitative Biology 2018-05-21 F. Fatehi Chenar , Y. N. Kyrychko , K. B. Blyuss

We consider a spatially-heterogeneous generalization of a well-established model for the dynamics of the Human Immunodeficiency Virus-type 1 (HIV) within a susceptible host. The model consists of a nonlinear system of three coupled…

Analysis of PDEs · Mathematics 2016-04-18 Stephen Pankavich , Christian Parkinson

The cellular adaptive immune response plays a key role in resolving influenza infection. Experiments where individuals are successively infected with different strains within a short timeframe provide insight into the underlying viral…

Populations and Evolution · Quantitative Biology 2016-11-24 Ada W. C. Yan , Pengxing Cao , Jane M. Heffernan , Jodie McVernon , Kylie M. Quinn , Nicole L. La Gruta , Karen L. Laurie , James M. McCaw

Viruses evolve in the background of host immune systems that exert selective pressure and drive viral evolutionary trajectories. This interaction leads to different evolutionary patterns in antigenic space. Examples observed in nature…

Populations and Evolution · Quantitative Biology 2020-11-20 Jacopo Marchi , Michael Lässig , Thierry Mora , Aleksandra M. Walczak

We have studied the dynamic evolution of the Covid-19 pandemic in Argentina. The marked heterogeneity in population density and the very extensive geography of the country becomes a challenge itself. Standard compartment models fail when…

Populations and Evolution · Quantitative Biology 2021-01-01 Nadia L. Barreiro , Tzype Govezensky , Pablo G. Bolcatto , Rafael A. Barrio
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