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In this Habilitation Thesis, I synthesize 10 years of work on the role of the motor system in sensorimotor decision-making. First, a large part of the work we initially performed (2014-2020) questioned the functional role of the motor…

Neurons and Cognition · Quantitative Biology 2023-06-22 Gerard Derosiere

The relationship between a neuron's complex inputs and its spiking output defines the neuron's coding strategy. This is frequently and effectively modeled phenomenologically by one or more linear filters that extract the components of the…

Neurons and Cognition · Quantitative Biology 2011-11-02 Michael Famulare , Adrienne L. Fairhall

In neuroscience, an important aspect of understanding the function of a neural circuit is to determine which, if any, of the neurons in the circuit are vital for the biological behavior governed by the neural circuit. A similar problem is…

Computational Complexity · Computer Science 2020-06-24 Vidya Sagar Sharma , Piyush Srivastava

Most decisions require information gathering from a stimulus presented with different gaps. Indeed, the brain process of this integration is rarely ambiguous. Recently, it has been claimed that humans can optimally integrate the information…

Neurons and Cognition · Quantitative Biology 2018-10-29 Maryam Tohidi-Moghaddam , Sajjad Zabbah , Farzaneh Olianezhad , Reza Ebrahimpour

Neurons in the brain represent external stimuli via neural codes. These codes often arise from stereotyped stimulus-response maps, associating to each neuron a convex receptive field. An important problem confronted by the brain is to infer…

Neurons and Cognition · Quantitative Biology 2015-02-25 Carina Curto , Vladimir Itskov , Alan Veliz-Cuba , Nora Youngs

Many real-life decisions involve both perceptual processes and weighing the consequences of different actions. However, the neural mechanisms underlying perceptual decisions have typically been examined separately from those underlying…

Neurons and Cognition · Quantitative Biology 2025-02-07 Xiaoyue Zhu , Jeffrey C. Erlich

We take the testing perspective to understand what the minimal discrimination time between two stimuli is for different types of rate coding neurons. Our main goal is to describe the testing abilities of two different encoding systems:…

Statistics Theory · Mathematics 2024-02-14 Guilherme Ost , Patricia Reynaud-Bouret

Animals rely on different decision strategies when faced with ambiguous or uncertain cues. Depending on the context, decisions may be biased towards events that were most frequently experienced in the past, or be more explorative. A…

Neurons and Cognition · Quantitative Biology 2023-05-10 Younes Bouhadjar , Dirk J. Wouters , Markus Diesmann , Tom Tetzlaff

Deep learning techniques are increasingly being adopted for classification tasks over the past decade, yet explaining how deep learning architectures can achieve state-of-the-art performance is still an elusive goal. While all the training…

Machine Learning · Computer Science 2021-10-12 Sakib Mostafa , Debajyoti Mondal

A cell routinely responds to one of many competing environmental cues. A fundamental question is whether the cell follows the cue prioritized by its internal signaling network or the cue that carries the most external information. We…

Biological Physics · Physics 2025-06-26 Louis Gonzalez , Hogyeong Gwak , Bumsoo Han , Andrew Mugler

Convolutional neural networks (CNNs) in recent years have made a dramatic impact in science, technology and industry, yet the theoretical mechanism of CNN architecture design remains surprisingly vague. The CNN neurons, including its…

Machine Learning · Computer Science 2019-07-16 Kamil Adamczewski , Mijung Park

Mounting evidence in neuroscience suggests the possibility of neuronal representations that individual neurons serve as the substrates of different mental representations in a point-to-point way. Combined with associationism, it can…

Neurons and Cognition · Quantitative Biology 2021-09-06 Chiyin Zheng

The categorization properties of an attractor network of three-state neurons which infers three-state concepts from examples are studied. The evolution equations governing the parallel dynamics at zero temperature for the overlap between…

Disordered Systems and Neural Networks · Physics 2009-10-30 D. R. C. Dominguez , D. Bollé

Cellular decision-making based on information received from the external environment is frequently initiated by transmembrane receptors. These receptors are known to propagate such information by triggering a series of irreversible,…

Biological Physics · Physics 2026-05-13 Samuel L. Foley , Margaret E. Johnson

This paper introduces a class of objects called decision rules that map infinite sequences of alternatives to a decision space. These objects can be used to model situations where a decision maker encounters alternatives in a sequence such…

Theoretical Economics · Economics 2022-09-12 Bhavook Bhardwaj , Siddharth Chatterjee

Understanding the information processing roles of cortical circuits is an outstanding problem in neuroscience and artificial intelligence. The theoretical setting of Bayesian inference has been suggested as a framework for understanding…

Neurons and Cognition · Quantitative Biology 2018-08-06 Dileep George , Alexander Lavin , J. Swaroop Guntupalli , David Mely , Nick Hay , Miguel Lazaro-Gredilla

In this article we present the modeling of bi-stability view problems described by the activity or firing rates of two interacting population of neurons. Starting from the study of a complex system, the sys-tem of stochastic differential…

Analysis of PDEs · Mathematics 2014-11-27 S Mancini

Neurons in the brain are often finely tuned for specific task variables. Moreover, such disentangled representations are highly sought after in machine learning. Here we mathematically prove that simple biological constraints on neurons,…

Neurons and Cognition · Quantitative Biology 2023-04-04 James C. R. Whittington , Will Dorrell , Surya Ganguli , Timothy E. J. Behrens

This paper demonstrates that some non-classical models of human decision-making can be run successfully as circuits on quantum computers. Since the 1960s, many observed cognitive behaviors have been shown to violate rules based on classical…

Quantum Physics · Physics 2023-03-27 Dominic Widdows , Jyoti Rani , Emmanuel Pothos

A large repertoire of spatiotemporal activity patterns in the brain is the basis for adaptive behaviour. Understanding the mechanism by which the brain's hundred billion neurons and hundred trillion synapses manage to produce such a range…

Neurons and Cognition · Quantitative Biology 2010-10-14 Dante R. Chialvo