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Planning of biorefinery operations is complicated by the stochastic nature of physical and chemical characteristics of biomass feedstock, such as, moisture level and carbohydrate content. Biomass characteristics affect the performance of…

Optimization and Control · Mathematics 2021-05-05 Dahui Liu , Sandra Eksioglu , Mohammad Roni

We discuss velocity-jump models for chemotaxis of bacteria with an internal state that allows the velocity jump rate to depend on the memory of the chemoattractant concentration along their path of motion. Using probabilistic techniques, we…

Numerical Analysis · Mathematics 2011-11-23 Mathias Rousset , Giovanni Samaey

Tissue homeostasis, the biological process of maintaining a steady state in tissue via control of cell proliferation, death, and metabolic function, is essential for the development, growth, maintenance, and proper function of living…

Biological Physics · Physics 2025-01-15 KVS Chaithanya , Jan Rozman , Andrej Košmrlj , Rastko Sknepnek

We present a geometric framework to study the growth-division dynamics of cells and protocells, and demonstrate that self-reproduction emerges only when a system's growth dynamics and division strategy are mutually compatible. Using several…

Adaptation and Self-Organizing Systems · Physics 2025-11-21 Parth Pratim Pandey , Sanjay Jain

A recent burst of dynamic single-cell growth-division data makes it possible to characterize the stochastic dynamics of cell division control in bacteria. Different modeling frameworks were used to infer specific mechanisms from such data,…

Cell Behavior · Quantitative Biology 2017-03-22 Jacopo Grilli , Matteo Osella , Andrew S. Kennard , Marco Cosentino Lagomarsino

We measure different contributions to entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent…

Soft Condensed Matter · Physics 2023-01-25 Mark Olenik , Jake Turley , Stephen Cross , Helen Weavers , Paul Martin , Isaac Chenchiah , Tanniemola Liverpool

Biological systems are known to communicate by diffusing chemical signals in the surrounding medium. However, most of the recent literature has neglected the electron transfer mechanism occurring amongst living cells, and its role in…

Emerging Technologies · Computer Science 2015-02-23 Nicolo Michelusi , Sahand Pirbadian , Mohamed Y. El-Naggar , Urbashi Mitra

Growing tissue and bacterial colonies are active matter systems where cell divisions and cellular motion generate active stress. Although they operate in the non-equilibrium regime, these biological systems can form large-scale ordered…

Biological Physics · Physics 2019-05-28 Yusuf Ilker Yaman , Esin Demir , Roman Vetter , Askin Kocabas

We present numerical results obtained from the modelling of a stochastic, highly connected and mobile community. The spread of attributes like health, disease among the community members is simulated using cellular automata on a planar 2…

Populations and Evolution · Quantitative Biology 2020-08-26 Ishant Tiwari , Pradeep Sarin , Punit Parmananda

We consider a class of biologically-motivated stochastic processes in which a unicellular organism divides its resources (volume or damaged proteins, in particular) symmetrically or asymmetrically between its progeny. Assuming the final…

Quantitative Methods · Quantitative Biology 2016-07-20 Andrew Marantan , Ariel Amir

This study integrates pedestrian flow characteristics to formulate a mesoscopic cellular automata model tailored for simulating evacuations in large-scale scenarios. Departing from the conventional planar grid cell division, the model…

Physics and Society · Physics 2023-11-20 Wei Lv , Jinghui Wang , Zhiming Fang , Dun Mao

In literature, a stochastic model for spreading nodes in a cellular cell is available. Despite its existence, the current method does not offer any versatility in dealing with sectored layers. Of course, this needed adaptability could be…

Information Theory · Computer Science 2013-06-04 Mouhamed Abdulla , Yousef R. Shayan , Junho Baek

To accelerate the development of strategies for cartilage tissue engineering, models are necessary to study the interactions between cellular dynamics and scaffold (SC) porosity. In experiments, cells are seeded in a porous SC where over a…

Tissues and Organs · Quantitative Biology 2018-09-03 Simone Cassani , Sarah D. Olson

Developing epithelial tissues coordinate cell proliferation and mechanical forces to achieve proper size and shape. As epithelial cells tightly adhere together to form the confluent tissue, the distribution of cell areas significantly…

Biological Physics · Physics 2026-01-22 Michael F. Staddon , Natalie A. Dye , Marko Popović , Frank Jülicher

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

Bacteria often develop distinct phenotypes to adapt to environmental stress. In particular, they can produce biofilms, dense communities of bacteria that live in a complex extracellular matrix. Bacterial biofilms provide a safe haven from…

Quantitative Methods · Quantitative Biology 2025-08-29 Stephen Williams , Daravuth Cheam , Michele K. Nishiguchi , Suzanne S. Sindi , Shilpa Khatri , Erica M. Rutter

Bacteria live in environments that are continuously fluctuating and changing. Exploiting any predictability of such fluctuations can lead to an increased fitness. On longer timescales bacteria can "learn" the structure of these fluctuations…

Cell Behavior · Quantitative Biology 2021-01-05 Stefan Landmann , Caroline M. Holmes , Mikhail Tikhonov

Logarithmic growth-rates are fundamental observables for describing ecological systems and the characterization of their distributions with analytical techniques can greatly improve their comprehension. Here a neutral model based on a…

Populations and Evolution · Quantitative Biology 2025-01-24 E. Brigatti , S. Azaele

Large-scale manufacturing of induced pluripotent stem cells (iPSCs) is essential for cell therapies and regenerative medicines. Yet, iPSCs form large cell aggregates in suspension bioreactors, resulting in insufficient nutrient supply and…

Molecular Networks · Quantitative Biology 2023-10-12 Hua Zheng , Sarah W. Harcum , Jinxiang Pei , Wei Xie

In order to study the unstable step motion on vicinal crystal surfaces we devise vicinal Cellular Automata. Each cell from the colony has value equal to its height in the vicinal, initially the steps are regularly distributed. Another array…

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