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We describe an approach to model genetic regulatory networks at the level of promotion-inhibition circuitry through a class of stochastic spin models that includes spatial and temporal density fluctuations in a natural way. The formalism…

Statistical Mechanics · Physics 2018-03-08 J. Ricardo G. Mendonça , Mário J. de Oliveira

We study percolation on networks, which is used as a model of the resilience of networked systems such as the Internet to attack or failure and as a simple model of the spread of disease over human contact networks. We reformulate…

Statistical Mechanics · Physics 2014-11-20 Brian Karrer , M. E. J. Newman , Lenka Zdeborová

There is increasing evidence that dense networks occur in on-line social networks, recommendation networks and in the brain. In addition to being dense, these networks are often also scale-free, i.e. their degree distributions follow…

Physics and Society · Physics 2018-05-16 Owen T. Courtney , Ginestra Bianconi

Real-world growth processes and scalings have been broadly categorized into three growth regimes with distinctly different properties and driving forces. The first two are characterized by a positive and constant feedback between growth and…

Physics and Society · Physics 2025-03-20 Alain Govaert , André Teixeira , Emma Tegling

Random scale-free overlay topologies provide a number of properties like for example high resilience against failures of random nodes, small (average) diameter as well as good expansion and congestion characteristics that make them…

Networking and Internet Architecture · Computer Science 2013-07-16 Ingo Scholtes

Biased (degree-dependent) percolation was recently shown to provide new strategies for turning robust networks fragile and vice versa. Here we present more detailed results for biased edge percolation on scale-free networks. We assume a…

The rate equations are used to study the scale-free behavior of the weight distribution in evolving networks whose topology is determined only by degrees of preexisting vertices. An analysis of these equations shows that the degree…

Disordered Systems and Neural Networks · Physics 2007-05-23 W. Jezewski

Scale-free (SF) networks and small world networks have been found to occur in very diverse contexts. It is this striking universality which makes one look for widely applicable mechanisms which lead to the formation of such networks. In…

Disordered Systems and Neural Networks · Physics 2007-05-23 Markus Brede , John Finnigan

The shortest-path percolation (SPP) model aims at describing the consumption and eventual exhaustion of a network's resources. Starting from a network containing a macroscopic connected component, random pairs of nodes are sequentially…

We define and completely solve a content-based directed network whose nodes consist of random words and an adjacency rule involving perfect or approximate matches, for an alphabet with an arbitrary number of letters. The analytic expression…

Molecular Networks · Quantitative Biology 2007-05-23 Muhittin Mungan , Alkan Kabakcioglu , Duygu Balcan , Ayse Erzan

In many organisms the expression levels of each gene are controlled by the activation levels of known "Transcription Factors" (TF). A problem of considerable interest is that of estimating the "Transcription Regulation Networks" (TRN)…

Applications · Statistics 2010-11-09 Gareth M. James , Chiara Sabatti , Nengfeng Zhou , Ji Zhu

In this study, we employ a superstatistical approach to construct q exponential and q Maxwell Boltzmann complex networks, generalizing the concept of scale free networks. By adjusting the crossover parameter {\lambda}, we control the degree…

Physics and Society · Physics 2024-11-14 Huilin Wang , Weibing Deng

The well-known issue of reconstructing regulatory networks from gene expression measurements has been somewhat disrupted by the emergence and rapid development of single-cell data. Indeed, the traditional way of seeing a gene regulatory…

Molecular Networks · Quantitative Biology 2021-10-01 Ulysse Herbach

Contrary to many recent models of growing networks, we present a model with fixed number of nodes and links, where it is introduced a dynamics favoring the formation of links between nodes with degree of connectivity as different as…

Statistical Mechanics · Physics 2007-05-23 M. Baiesi , S. S. Manna

We show how to construct a reduced description of interacting genes in noisy, small regulatory networks using coupled binary "spin" variables. Treating both the protein number and gene expression state variables stochastically and on equal…

Molecular Networks · Quantitative Biology 2015-05-13 Aleksandra M. Walczak , Peter G. Wolynes

We introduce a self-organized model of graph evolution associated with preferential network random walkers. The idea is developed by using two different types of walkers, the interactions of which lead to a dynamic graph. The walkers of the…

Statistical Mechanics · Physics 2012-06-01 S. Mehraban , M. R. Ejtehadi

We analyse growing networks ranging from collaboration graphs of scientists to the network of similarities defined among the various transcriptional profiles of living cells. For the explicit demonstration of the scale-free nature and…

Statistical Mechanics · Physics 2009-11-10 I. Farkas , I. Derenyi , H. Jeong , Z. Neda , Z. N. Oltvai , E. Ravasz , A. Schubert , A. -L. Barabasi , T. Vicsek

Preferential attachment --- by which new nodes attach to existing nodes with probability proportional to the existing nodes' degree --- has become the standard growth model for scale-free networks, where the asymptotic probability of a node…

Adaptation and Self-Organizing Systems · Physics 2014-11-12 Michael Small , Yingying Li , Thomas Stemler , Kevin Judd

In many networks such as transportation or communication networks, distance is certainly a relevant parameter. In addition, real-world examples suggest that when long-range links are existing, they usually connect to hubs-the well connected…

Disordered Systems and Neural Networks · Physics 2009-11-07 Marc Barthelemy

We introduce a minimal model description for the dynamics of transcriptional regulatory networks. It is studied within a mean-field approximation, i.e., by deterministic ode's representing the reaction kinetics, and by stochastic…

Molecular Networks · Quantitative Biology 2009-11-13 R. Blossey , C. V. Giuraniuc