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Modelling the dynamics of interactions in a neuronal ensemble is an important problem in functional connectivity research. One popular framework is latent factor models (LFMs), which have achieved notable success in decoding neuronal…

Methodology · Statistics 2023-05-18 Meixi Chen , Martin Lysy , David Moorman , Reza Ramezan

We analyze the connectivity structure of weighted brain networks extracted from spontaneous magnetoencephalographic (MEG) signals of healthy subjects and epileptic patients (suffering from absence seizures) recorded at rest. We find that,…

Data Analysis, Statistics and Probability · Physics 2011-01-21 M. Chavez , M. Valencia , V. Navarro , V. Latora , J. Martinerie

Sequential neural activity is fundamental to cognition, yet how diverse sequences are recalled under biological constraints remains a key question. Existing models often struggle to balance biophysical realism and analytical tractability.…

Neurons and Cognition · Quantitative Biology 2025-12-04 Genki Shimizu , Taro Toyoizumi

Synaptic plasticity is vital for learning and memory in the brain. It consists of long-term potentiation (LTP) and long-term depression (LTD). Spike frequency is one of the major components of synaptic plasticity in the brain, a noisy…

Neurons and Cognition · Quantitative Biology 2021-08-13 Yuto Takeda , Katsuhiko Hata , Tokio Yamasaki , Masaki Kaneko , Osamu Yokoi , Chengta Tsai , Kazuo Umemura , Tetsuro Nikuni

Functions of brain areas in complex animals are believed to rely on the dynamics of networks of neurons rather than on single neurons. On the other hand, the network dynamics reflect and arise from the integration and coordination of the…

Neurons and Cognition · Quantitative Biology 2017-01-03 Stefano Cavallari

The various human brain tasks are performed at different locations and time scales. Yet, we discovered the existence of time-invariant (above an essential time scale) partitioning of the brain activity into personal state-specific frequency…

Medical Physics · Physics 2009-11-11 Itai Doron , Eyal Hulata , Itay Baruchi , Vernon L. Towle , Eshel Ben-Jacob

Precise spatio-temporal patterns of neuronal action potentials underly e.g. sensory representations and control of muscle activities. However, it is not known how the synaptic efficacies in the neuronal networks of the brain adapt such that…

Neurons and Cognition · Quantitative Biology 2015-02-24 Christian Albers , Maren Westkott , Klaus Pawelzik

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

Working memory plays a crucial role in various aspects of human life. Therefore, it has been an area of interest in different research studies, especially neuroscience. The neuroscientists investigating working memory have primarily…

Neurons and Cognition · Quantitative Biology 2024-11-26 Sepehr Gourabi , Masoud Lotfalipour , Reza Khosrowabadi , Reza Jafari

The proposed analysis of the currently available experimental results concerning the neural cell activity in the brain area known as hippocampus suggests a particular mechanism of spatial information and memory processing. Below it is…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Yu. Dabaghian , A. G. Cohn , L. Frank

Space is represented in the mammalian brain by the activity of hippocampal place cells as well as in their spike-timing correlations. Here we propose a theory how this temporal code is transformed to spatial firing rate patterns via…

Neurons and Cognition · Quantitative Biology 2017-08-02 Mauro M. Monsalve-Mercado , Christian Leibold

Small-World Networks (SWNs) represent a fundamental model for the comprehension of many complex man-made and biological networks. In the central nervous system, SWN models have been shown to fit well both anatomical and functional maps at…

Little is currently known about the coordination of neural activity over longitudinal time-scales and how these changes relate to behavior. To investigate this issue, we used resting-state fMRI data from a single individual to identify the…

Neurons and Cognition · Quantitative Biology 2017-05-30 James M. Shine , Oluwasanmi Koyejo , Russell A. Poldrack

In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

Neurons and Cognition · Quantitative Biology 2019-03-29 Peter Helfer , Thomas R. Shultz

Neuron is a noisy information processing unit and conventional view is that information in the cortex is carried on the rate of neurons spike emission. More recent studies on the activity propagation through the homogeneous network have…

Neurons and Cognition · Quantitative Biology 2007-05-23 Kosuke Hamaguchi , Masato Okada , Kazuyuki Aihara

The cortical processes involved in learning are not well understood. Recent experiments have studied population-level response in the orofacial somatosensory (S1) and motor (S1) cortices of rhesus macaque monkeys during adaptation to a…

Neurons and Cognition · Quantitative Biology 2014-05-26 Alexander Conway , Fritzie Arce

Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

Neurons and Cognition · Quantitative Biology 2011-05-09 Paul Expert , Renaud Lambiotte , Dante R. Chialvo , Kim Christensen , Henrik Jeldtoft Jensen , David J. Sharp , Federico Turkheimer

The spiking activity of the hippocampal place cells plays a key role in producing and sustaining an internalized representation of the ambient space---a cognitive map. These cells do not only exhibit location-specific spiking during…

Neurons and Cognition · Quantitative Biology 2018-11-05 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

How human brain function emerges from structure has intrigued researchers for decades and numerous models have been put forward, yet none of them yields a close structure-function relation. Here we present a resonance model based on…

Neurons and Cognition · Quantitative Biology 2022-10-10 Yanjiang Wang , Jichao Ma , Jiebin Luo , Xue Chen , Yue Yuan

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow