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Topological techniques have become a popular tool for studying information flows in neural networks. In particular, simplicial homology theory is used to analyze how cognitive representations of space emerge from large conglomerates of…

Neurons and Cognition · Quantitative Biology 2025-02-19 Andrey Babichev , Vladimir Vashin , Yuri Dabaghian

A diverse white matter network and finely tuned neuronal membrane properties allow the brain to transition seamlessly between cognitive states. However, it remains unclear how static structural connections guide the temporal progression of…

Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed…

Neurons and Cognition · Quantitative Biology 2022-07-19 Yan-Liang Shi , Roxana Zeraati , Anna Levina , Tatiana A. Engel

Neural synchrony in the brain at rest is usually variable and intermittent, thus intervals of predominantly synchronized activity are interrupted by intervals of desynchronized activity. Prior studies suggested that this temporal structure…

Quantitative Methods · Quantitative Biology 2021-04-26 Joel Zirkle , Leonid L Rubchinsky

We present a new statistical method to analyze multichannel steady-state local field potentials (LFP) recorded within different sensory cortices of different rodent species. Our spatiotemporal multi-dimensional cluster statistics (MCS)…

Quantitative Methods · Quantitative Biology 2016-11-24 Patrick Krauss , Claus Metzner , Achim Schilling , Konstantin Tziridis , Maximilian Traxdorf , Holger Schulze

Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…

Neurons and Cognition · Quantitative Biology 2020-07-01 Richard F. Betzel , Katherine C. Wood , Christopher Angeloni , Maria Neimark Geffen , Danielle S. Bassett

One of the main goals of neuroscience is to understand how an organism's cognitive capacities or physiological states are potentially related to brain activities that involve the interaction of multiple brain structures and cortical areas.…

Neurons and Cognition · Quantitative Biology 2023-09-06 Eduardo C. Padovani

Converging research suggests that the resting brain operates at the cusp of dynamic instability signified by scale-free temporal correlations. We asked if the scaling properties of these correlations differ between amplitude and phase…

Neurons and Cognition · Quantitative Biology 2015-12-09 Robert Ton , Gustavo Deco , Morten L Kringelbach , Mark Woolrich , Andreas Daffertshofer

Recent advances in neural recording technology allow simultaneously recording action potentials from hundreds to thousands of neurons in awake, behaving animals. However, characterizing spike patterns in the resulting data, and linking…

Working memory (WM) has been intensively used to enable the temporary storing of information for processing purposes, playing an important role in the execution of various cognitive tasks. Recent studies have shown that information in WM is…

Neurons and Cognition · Quantitative Biology 2022-05-19 Thi Kim Thoa Thieu , Roderick Melnik

In "The Organization of Behavior" (Hebb, 1949), Hebb suggested that the propagation of activity between transiently grouped neurons plays an important role in behavior. Since then, multiple studies have provided evidence supporting Hebb's…

Neurons and Cognition · Quantitative Biology 2021-05-28 Ohad Felsenstein , Moshe Abeles

In vivo, neurons establish functional connections and preserve information along their synaptic pathways from one information processing stage to the next in a very efficient manner. Paired spiking (PS) enhancement plays a key role by…

Neurons and Cognition · Quantitative Biology 2015-11-02 Aurel Vasile Martiniuc , Victor Bocoş-Binţinţan , Rouhollah Habibey , Asiyeh Golabchi , Alois Knoll , Axel Blau

Synchronization in neural system plays an important role in many brain functions. Synchronization in the gamma frequency band (30Hz-100Hz) is involved in a variety of cognitive phenomena; abnormalities of the gamma synchronization are found…

Neurons and Cognition · Quantitative Biology 2021-04-26 Quynh-Anh Nguyen , Leonid L Rubchinsky

We theoretically investigate long-term potentiation (LTP) in the hippocampus using a simple model of a neuron stimulated by three different time-structured input signals (regular, Markov, and chaotic). The synaptic efficacy change is…

Disordered Systems and Neural Networks · Physics 2009-10-30 M. Tatsuno , Y. Aizawa

Place cells in the rat hippocampus play a key role in creating the animal's internal representation of the world. During active navigation, these cells spike only in discrete locations, together encoding a map of the environment.…

Neurons and Cognition · Quantitative Biology 2016-03-22 Yuri Dabaghian

The timing of individual neuronal spikes is essential for biological brains to make fast responses to sensory stimuli. However, conventional artificial neural networks lack the intrinsic temporal coding ability present in biological…

Neural and Evolutionary Computing · Computer Science 2020-11-18 Iulia M. Comsa , Krzysztof Potempa , Luca Versari , Thomas Fischbacher , Andrea Gesmundo , Jyrki Alakuijala

Self-sustained activity in the brain is observed in the absence of external stimuli and contributes to signal propagation, neural coding, and dynamic stability. It also plays an important role in cognitive processes. In this work, by means…

The mammalian hippocampus plays a principal role in producing a cognitive map of space---an internalized representation of the animal's environment. The neuronal mechanisms producing this map depend primarily on the temporal structure of…

Neurons and Cognition · Quantitative Biology 2016-03-22 Edward Basso , Mamiko Arai , Yuri Dabaghian

The hippocampus has the capacity for reactivating recently acquired memories [1-3] and it is hypothesized that one of the functions of sleep reactivation is the facilitation of consolidation of novel memory traces [4-11]. The dynamic and…

Neurons and Cognition · Quantitative Biology 2015-06-26 Piotr Jablonski , Gina R. Poe , Michal Zochowski

Frequency discrimination is a fundamental task of the auditory system. The mammalian inner ear, or cochlea, provides a place code in which different frequencies are detected at different spatial locations. However, a temporal code based on…

Neurons and Cognition · Quantitative Biology 2015-06-05 Tobias Reichenbach , A. J. Hudspeth