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We develop, discuss, and compare several inference techniques to constrain theory parameters in collider experiments. By harnessing the latent-space structure of particle physics processes, we extract extra information from the simulator.…

High Energy Physics - Phenomenology · Physics 2018-09-19 Johann Brehmer , Kyle Cranmer , Gilles Louppe , Juan Pavez

Large-scale applications of energy density functional (EDF) methods depend on fast and reliable algorithms to solve the associated non-linear self-consistency problem. When dealing with large single-particle variational spaces, existing…

Nuclear Theory · Physics 2019-06-24 W. Ryssens , M. Bender , P. -H. Heenen

Molecular dynamics (MD) simulations are essential tools for unraveling atomistic insights into the structure and dynamics of condensed-phase systems. However, the universal and accurate prediction of macroscopic properties from ab initio…

A method for automatic computation of parameter derivatives of numerically computed light scattering signals is demonstrated. The finite-element based method is validated in a numerical convergence study, and it is applied to investigate…

Optics · Physics 2013-04-17 S. Burger , L. Zschiedrich , J. Pomplun , F. Schmidt , B. Bodermann

We present a convergence result for the finite volume method applied to a particular phase field problem suitable for simulation of pure substance solidification. The model consists of the heat equation and the phase field equation with a…

Numerical Analysis · Mathematics 2020-10-14 Aleš Wodecki , Pavel Strachota , Michal Beneš

We present a new modeling paradigm for optimization that we call random field optimization. Random fields are a powerful modeling abstraction that aims to capture the behavior of random variables that live on infinite-dimensional spaces…

Optimization and Control · Mathematics 2022-01-26 Joshua L. Pulsipher , Benjamin R. Davidson , Victor M. Zavala

We present a systematic, top-down, thermodynamic parametrization scheme for dissipative particle dynamics (DPD) using water-octanol partition coefficients, supplemented by water-octanol phase equilibria and pure liquid phase density data.…

We propose a new molecular simulation framework that combines the transferability, robustness and chemical flexibility of an ab initio method with the accuracy and efficiency of a machine learned force field. The key to achieve this mix is…

Computational Physics · Physics 2020-01-08 Sebastian Dick , Marivi Fernandez-Serra

Machine-learning force fields (MLFFs) have emerged as a promising solution for speeding up ab initio molecular dynamics (MD) simulations, where accurate force predictions are critical but often computationally expensive. In this work, we…

In this paper, a novel isogeometric method for Biot's consolidation model is constructed and analyzed, using a four-field formulation where the unknown variables are the solid displacement, solid pressure, fluid flux, and fluid pressure.…

Numerical Analysis · Mathematics 2025-02-14 Hanyu Chu , Luca Franco Pavarino

We describe a new computational method for the numerically stable particle-based simulation of open-boundary flows, including volume conserving chemical reactions. The novel method is validated for the case of heterogeneous catalysis…

Adaptation and Self-Organizing Systems · Physics 2020-10-09 Sebastian Mühlbauer , Severin Strobl , Thorsten Pöschel

Lipid vesicles appear ubiquitously in biological systems. Understanding how the mechanical and intermolecular interations deform vesicle membrane is a fundamental question in biophysics. In this article we developed a fast algorithm to…

Numerical Analysis · Mathematics 2014-11-17 Michael Mikucki , Y. C. Zhou

Classical empirical force fields have dominated biomolecular simulation for over 50 years. Although widely used in drug discovery, crystal structure prediction, and biomolecular dynamics, they generally lack the accuracy and transferability…

In the field of topology optimization, the homogenization approach has been revived as an important alternative to the established, density-based methods because it can represent the microstructural design at a much finer length-scale than…

Computational Geometry · Computer Science 2022-05-17 Florian Cyril Stutz , Tim Felle Olsen , Jeroen Peter Groen , Niels Aage , Ole Sigmund , Justin Solomon , Jakob Andreas Bærentzen

Pipeline parallelism enables training models that exceed single-device memory, but practical throughput remains limited by pipeline bubbles. Although parameter freezing can improve training throughput by adaptively skipping backward…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-09 Seonghye Cho , Jaemin Han , Hyunjin Kim , Euisoo Jung , Jae-Gil Lee

We explore the pressure dependence of a set of properties of simple monohydric alcohols, namely of methanol, ethanol and 1-propanol, by using isobaric-isothermal molecular dynamics computer simulations. A recently proposed united atom,…

Soft Condensed Matter · Physics 2026-03-31 M. Aguilar , L. Pusztai , O. Pizio

The finite-element method is a preferred numerical method when electromagnetic fields at high accuracy are to be computed in nano-optics design. Here, we demonstrate a finite-element method using hp-adaptivity on tetrahedral meshes for…

The effectiveness of a new algorithm, parallel tempering, is studied for numerical simulations of biological molecules. These molecules suffer from a rough energy landscape. The resulting slowing down in numerical simulations is overcome by…

Chemical Physics · Physics 2009-10-30 Ulrich H. E. Hansmann

Methodologies for creating reactive potential energy surfaces from molecular mechanics force-fields are becoming increasingly popular. To date, molecular mechanics force-fields use harmonic expressions to treat bonding stretches, which is a…

Chemical Physics · Physics 2019-05-22 R. J. Shannon , B. Hornung , D. P. Tew , D. R. Glowacki

An efficient and robust on-the-fly machine learning force field method is developed and integrated into an electronic-structure code. This method realizes automatic generation of machine learning force fields on the basis of Bayesian…

Materials Science · Physics 2019-07-24 Ryosuke Jinnouchi , Ferenc Karsai , Georg Kresse