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The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…
Positronium imaging was recently proposed to image the properties of positronium atoms in the patient body. Positronium properties depend on the size of intramolecular voids and oxygen concentration; therefore, they deliver information…
A major strength of iterative algorithms used in positron emission tomography (PET) lies in their abilities to introduce precise models of the physics at play, which includes the statistical nature of the detection processes, and a detailed…
Space radiation remains one of the primary hazards to spaceflight crews. The unique nature of the intravehicular radiation spectrum makes prediction of biological outcomes difficult, with computational simulation-based efforts stymied by…
Capturing depth and reflectivity images at low light levels from active illumination of a scene has wide-ranging applications. Conventionally, even with single-photon detectors, hundreds of photon detections are needed at each pixel to…
Monte Carlo simulations are a crucial tool for the analysis and prediction of various background components in liquid xenon (LXe) detectors. With improving shielding in new experiments, the simulation of external backgrounds, such as…
Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…
The main challenges posed by the design of future Positron Emission Tomography machines are the improvement of the spatial and timing resolution and the combined operation with magnetic resonance. The Micro Pixel Photon Counter by Hamamatsu…
The potential of photon detectors to achieve precise timing information is of increasing importance in many domains, PET and CT scanners in medical imaging and particle physics detectors, amongst others. The goal to increase by an order of…
We studied the application of statistical reconstruction algorithms, namely maximum likelihood and least squares methods, to the problem of event reconstruction in a dual phase liquid xenon detector. An iterative method was developed for…
We describe the results of detailed 3-D Monte Carlo simulations of a "CZT calorimeter" that can be used to detect photons in the keV to several MeV range. Several astrophysics applications require the detection of photons in the energy…
In order to develop a high spatial resolution (micron level) thermal neutron detector, a detector assembly composed of cerium doped lithium glass microfibers, each with a diameter of 1\,$\mu$m, is proposed, where the neutron absorption…
Liquid xenon offers several features, which make it suitable for applications in nuclear medicine, such as high scintillation yield and fast scintillation decay time. Moreover, being a continuous medium with a uniform response, liquid xenon…
Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…
The National Electrical Manufacturers Association's (NEMA) NU 4-2008 standard specifies methodology for evaluating the performance of small-animal PET scanners. The standard's goal is to enable comparison of different PET scanners over a…
We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…
In computed tomography (CT) reconstruction, scattering causes server quality degradation of the reconstructed CT images by introducing streaks and cupping artifacts which reduce the detectability of low contrast objects. Monte Carlo (MC)…
We demonstrate the importance and utility of Monte Carlo simulation of single-photon detectors. Devising an optimal simulation is strongly influenced by the particular application because of the complexity of modern, avalanche-diode-based…
This work aims at applying the theory of the component-based normalization for the Jagiellonian PET scanner, currently under development at the Jagiellonian University. In any Positron Emission Tomography acquisition, efficiency along a…
The TT-PET collaboration is developing a small animal TOF-PET scanner based on silicon detectors featuring 30 ps RMS time resolution and intended to be inserted in an existing MRI scanner. The TT-PET scanner makes use of a stack of layers…