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We consider a system of $N$ identical independent Markov processes, each taking values 0 or 1. The system describes a stochastic dynamics of an ensemble of two-level atoms. The atoms are exposed to a photon flux. Under the photon flux…

Probability · Mathematics 2019-05-01 E. Pechersky , S. Pirogov , G. M. Schütz , A. Vladimirov , A. Yambartsev

An important task in quantitative biology is to understand the role of stochasticity in biochemical regulation. Here, as an extension of our recent work [Phys. Rev. Lett. 107, 148101 (2011)], we study how input fluctuations affect the…

Molecular Networks · Quantitative Biology 2015-06-11 Bo Hu , David A. Kessler , Wouter-Jan Rappel , Herbert Levine

We study the stochastic evolution of four species in cyclic competition in a well mixed environment. In systems composed of a finite number $N$ of particles these simple interaction rules result in a rich variety of extinction scenarios,…

Statistical Mechanics · Physics 2012-07-09 C. H. Durney , S. O. Case , M. Pleimling , R. K. P. Zia

A theoretical treatment of deeply supercooled liquids is difficult because their properties emerge from spatial inhomogeneities that are self-induced, transient, and nanoscopic. I use computer simulations to analyse self-induced static and…

Statistical Mechanics · Physics 2021-08-24 Ludovic Berthier

In this paper I show that, for a class of reaction networks, the discrete stochastic nature of the reacting species and reactions results in qualitative and quantitative differences between the mean of exact stochastic simulations and the…

Other Quantitative Biology · Quantitative Biology 2008-01-03 Chetan J Gadgil

Discrete autonomous dynamical systems in dimension 1 can exhibit chaotic behavior, whereas the corresponding continuous evolution equations rule it out, and cannot even possess a nontrivial periodic solution. Therefore the passage from…

Other Condensed Matter · Physics 2016-08-31 Hubert Krivine , Annick Lesne , Jacques Treiner

Molecular dynamics simulations use statistical mechanics at the atomistic scale to enable both the elucidation of fundamental mechanisms and the engineering of matter for desired tasks. The behavior of molecular systems at the microscale is…

Computational Physics · Physics 2020-12-25 Wujie Wang , Simon Axelrod , Rafael Gómez-Bombarelli

The paper gives a systematic analysis of singularities of transition processes in dynamical systems. General dynamical systems with dependence on parameter are studied. A system of relaxation times is constructed. Each relaxation time…

chao-dyn · Physics 2009-01-28 A. N. Gorban

We study classical stochastic systems with discrete states, coupled to switching external environments. For fast environmental processes we derive reduced dynamics for the system itself, focusing on corrections to the adiabatic limit of…

Statistical Mechanics · Physics 2019-03-27 Peter G. Hufton , Yen Ting Lin , Tobias Galla

We have investigated by molecular dynamics method the influence of a finite number of particles used in computer simulations on fluctuations of thermodynamic properties. As a case study, we used the two-dimensional Lennard-Jones system. 2D…

Statistical Mechanics · Physics 2024-03-05 M. V. Kondrin , Y. B. Lebed

Traditionally, it is understood that fluctuations in the equilibrium distribution are not evident in thermodynamic systems of large $N$ (the number of particles in the system) \cite{Huang1}. In this paper we examine the validity of this…

Mathematical Physics · Physics 2007-10-03 Kieran Kelly , Przemysław Repetowicz , Seosamh macRéamoinn

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as…

Biological Physics · Physics 2018-05-02 F. Gnesotto , F. Mura , J. Gladrow , C. P. Broedersz

Species extinction is a core process that affects the diversity of life on Earth. Competition between species in a population is considered by ecological niche-based theories as a key factor leading to different severity of species…

Populations and Evolution · Quantitative Biology 2020-07-28 Ivan Sudakov , Sergey A. Vakulenko , John T. Bruun

We consider a model for substrate-depletion oscillations in genetic systems, based on a stochastic differential equation with a slowly evolving external signal. We show the existence of critical transitions in the system. We apply two…

Chaotic Dynamics · Physics 2014-03-13 Jesse Berwald , Marian Gidea

Biological systems are characterized by the ubiquitous roles of weak, that is, non-covalent molecular interactions, small, often very small, numbers of specific molecules per cell, and Brownian motion. These combine to produce stochastic…

Cell Behavior · Quantitative Biology 2023-04-27 Michael W. Klymkowsky

We examine a biomolecular machine involving a driven, observable process coupled to a hidden process in a kinetically cooperative manner. A stochastic thermodynamics framework is employed to analyze a fluctuation theorem for the…

Statistical Mechanics · Physics 2025-11-14 D. Evan Piephoff , Jianshu Cao

Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

Populations and Evolution · Quantitative Biology 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

Far too often are multiparticle final states studied and models tested on merely single-particle spectra and their integrals, the average multiplicities: A multiparticle final state is a non-linear, complex system and the essential…

High Energy Physics - Phenomenology · Physics 2017-08-23 Wolfram Kittel

The impact of random fluctuations on the dynamical behavior a complex biological systems is a longstanding issue, whose understanding would shed light on the evolutionary pressure that nature imposes on the intrinsic noise levels and would…

Molecular Networks · Quantitative Biology 2018-01-26 Fabrizio Pucci , Marianne Rooman

We study the probability distribution of a current flowing through a diffusive system connected to a pair of reservoirs at its two ends. Sufficient conditions for the occurrence of a host of possible phase transitions both in and out of…

Statistical Mechanics · Physics 2017-01-25 Yongjoo Baek , Yariv Kafri , Vivien Lecomte
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