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This thesis centres on the development of multidimensional fluorescence imaging tools, with a particular emphasis on fluorescence lifetime imaging (FLIM) microscopy for application to biological research. The key aspects of this thesis are…

Instrumentation and Detectors · Physics 2017-08-14 Egidijus Auksorius

The particle-in-cell approach has proven effective at modeling neutron star and black hole magnetospheres from first principles, but global simulations are plagued with an unrealistically small separation between the scales where…

High Energy Astrophysical Phenomena · Physics 2024-10-09 Adrien Soudais , Benoît Cerutti , Ioannis Contopoulos

Superresolution techniques based on intensity measurements after a spatial mode decomposition can overcome the precision of diffraction-limited direct imaging. However, realistic measurement devices always introduce finite crosstalk in any…

Quantum Physics · Physics 2020-09-02 Manuel Gessner , Claude Fabre , Nicolas Treps

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate…

Soft Condensed Matter · Physics 2015-02-16 Sukumar Rajauria , Christopher Axline , Claudia Gottstein , Andrew N. Cleland

Cutting edge deep learning techniques allow for image segmentation with great speed and accuracy. However, application to problems in materials science is often difficult since these complex models may have difficultly learning physical…

Image and Video Processing · Electrical Eng. & Systems 2019-12-13 James P. Horwath , Dmitri N. Zakharov , Remi Megret , Eric A. Stach

High performance materials, from natural bone over ancient damascene steel to modern superalloys, typically possess a complex structure at the microscale. Their properties exceed those of the individual components and their knowledge-based…

Materials Science · Physics 2019-03-25 Carl Kusche , Tom Reclik , Martina Freund , Talal Al-Samman , Ulrich Kerzel , Sandra Korte-Kerzel

The ongoing development of single electron, nano and atomic scale semiconductor devices would benefit greatly from a characterization tool capable of detecting single electron charging events with high spatial resolution, at low…

Mesoscale and Nanoscale Physics · Physics 2024-03-22 José Bustamante , Yoichi Miyahara , Logan Fairgrieve-Park , Kieran Spruce , Patrick See , Neil Curson , Taylor Stock , Peter Grutter

We demonstrate the existence of different density-density functionals designed to retain selected properties of the many-body ground state in a non-interacting solution starting from the standard density functional theory ground state. We…

Other Condensed Matter · Physics 2009-11-13 F. A. Reboredo , P. R. C. Kent

We present a quantum sensing scheme achieving the ultimate quantum sensitivity in the estimation of the transverse displacement between two photons interfering at a balanced beam splitter, based on transverse-momentum sampling measurements…

Quantum Physics · Physics 2024-05-03 Danilo Triggiani , Vincenzo Tamma

A nonlinear block-coupled Finite Volume methodology is developed for large displacement and large strain regime. The new methodology uses the same normal and tangential face derivative discretisations found in the original fully coupled…

Computational Engineering, Finance, and Science · Computer Science 2020-09-15 L. R. Azevedo , P. Cardiff , F. J. Galindo-Rosales , M. Schafer

Compression of micro-pillars is followed in situ by a quick nano-focused X-ray scanning microscopy technique combined with three-dimensional reciprocal space mapping. Compared to other attempts using 2 X-ray nanobeams, it avoids any motion…

We present results of a planar process development based on the combination of electron-beam lithography and dry etching for fabricating high-quality superconducting photosensitive structures in the sub-100nm regime. The devices were…

Mesoscale and Nanoscale Physics · Physics 2010-11-23 H. Bartolf , K. Inderbitzin , L. B. Gómez , A. Engel , A. Schilling

The statistical effects of different conditions in physical vapor deposition, such as sputter deposition, have on thin film morphology has long been the subject of interest. One notable effect is that of column development due to…

Materials Science · Physics 2018-02-26 William J. Meese , Toh-Ming Lu

The concept of lumped optical nanoelements (or metactronics), wherein nanometer-scale structures act as nanoinductors, nanocapacitors and nanoresistors, has attracted a great deal of attention as a simple toolbox for engineering different…

Optics · Physics 2021-06-18 Pujuan Ma , Lei Gao , Pavel Ginzburg , Roman E. Noskov

The determination of the neutrino mass is an open issue in modern particle physics and astrophysics. The direct mass measurement is the only theory-unrelated experimental tool capable to probe such quantity. The HOLMES experiment aims to…

Nitrogen-vacancy centres (NVs) are promising solid-state nanoscale quantum sensors for applications ranging from material science to biotechnology. Using multiple sensors simultaneously offers advantages for probing spatiotemporal…

Quantum Physics · Physics 2025-11-17 Hao-Cheng Weng , John G. Rarity , Krishna C. Balram , Joe A. Smith

Localization microscopy is an imaging technique in which the positions of individual nanoscale point emitters (e.g. fluorescent molecules) are determined at high precision from their images. This is the key ingredient in…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Elias Nehme , Daniel Freedman , Racheli Gordon , Boris Ferdman , Lucien E. Weiss , Onit Alalouf , Reut Orange , Tomer Michaeli , Yoav Shechtman

The exciting field of stretchable electronics (SE) promises numerous novel applications, particularly in-body and medical diagnostics devices. However, future advanced SE miniature devices will require high-density, extremely stretchable…

Instrumentation and Detectors · Physics 2017-09-14 Salman Shafqat , Johan P. M. Hoefnagels , Angel Savov , Shivani Joshi , Ronald Dekker , Marc G. D. Geers

Wrinkle defects were found widely exist in the field of industrial products, i.e. wind turbine blades and filament-wound composite pressure vessels. The magnitude of wrinkle wavelength varies from several millimeters to over one hundred…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Li Ma , Shoulong Wang , Changchen Liu , Ange Wen , Kaidi Ying , Jing Guo

This study presents a novel, versatile traction force microscopy framework for quantifying three-dimensional (3D) interfacial forces during bio-adhesion by integrating in situ stereo digital image correlation with finite element (FE)…

Instrumentation and Detectors · Physics 2026-01-09 Yingwei Hou , Fusheng Wang , Tao Liu