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The zebrafish is a valuable model organism for studying cardiac development and diseases due to its many shared aspects of genetics and anatomy with humans and ease of experimental manipulations. Computational fluid-structure interaction…

Tissues and Organs · Quantitative Biology 2025-06-23 Alexander D. Kaiser , Jing Wang , Aaron L. Brown , Enbo Zhu , Tzung Hsiai , Alison L. Marsden

We have carried out a pilot study on a standard collection of electrocardiograms from patients who suffer from congestive heart failure, and subjects without cardiac pathology, using receiver-operating-characteristic (ROC) analysis. The…

chao-dyn · Physics 2007-05-23 Stefan Thurner , Markus C. Feurstein , Malvin C. Teich

Empirical observations in marine ecosystems have suggested a balance of biological and advection time scales as a possible explanation of species coexistence. To characterise this scenario, we measure the time to fixation in neutrally…

Populations and Evolution · Quantitative Biology 2018-04-09 Tobias Galla , Vicente Pérez-Muñuzuri

Network remodeling, or adaptation, in the presence of periodically driven forcings has hereto remained largely unexplored, despite the fact that a broad class of biological transport networks, e.g. animal vasculature, depends on periodic…

Adaptation and Self-Organizing Systems · Physics 2026-01-01 Purba Chatterjee , Eleni Katifori

The left ventricular end-systolic pressure-volume relationship (ESPVr) is a key indicator of cardiac contractility. Despite its established importance, several studies suggested that the mechanical mode of contraction, such as isovolumetric…

Medical Physics · Physics 2024-11-12 Francesco Regazzoni , Corrado Poggesi , Cecilia Ferrantini

Despite the widespread diffusion of nonlinear methods for heart rate variability (HRV) analysis, the presence and the extent to which nonlinear dynamics contribute to short-term HRV is still controversial. This work aims at testing the…

Human heart is a complex system that can be studied using its electrical activity recorded as Electrocardiogram (ECG). Any variations or anomalies in the ECG can indicate abnormalities in the cardiac dynamics. In this work, we present a…

Medical Physics · Physics 2020-01-08 Sneha Kachhara , G. Ambika

The mechanism that causes an interdecadal oscillation in a coarse resolution sector ocean model forced by mixed boundary conditions is studied. The oscillation is characterized by large fluctuations in convective activity and air/sea heat…

Atmospheric and Oceanic Physics · Physics 2008-02-03 G. Lenderink , R. J. Haarsma

It is shown that in the case of human heart rate, the scaling behaviour of the correlation sum (calculated by the Grassberger-Procaccia algorithm) is a result of the interplay of various factors: finite resolution of the apparatus…

Medical Physics · Physics 2007-05-23 M. Sakki , J. Kalda , M. Vainu , M. Laan

An analysis of the RR-interval time series, $t_i$, is presented for the case in which the average time, $\bar{t}$, changes slowly. In particular, $\bar{t}$ and a short-time scale variability parameter, $V$, are simultaneously measured while…

Quantitative Methods · Quantitative Biology 2007-05-23 P. B. Siegel , J. Sperber , W. Kindermann , A. Urhausen

In this paper we extend the earlier treatment of out-of-equilibrium mesoscopic fluctuations in glassy systems in several significant ways. First, via extensive simulations, we demonstrate that models of glassy behavior without quenched…

Statistical Mechanics · Physics 2009-11-10 C. Chamon , P. Charbonneau , L. F. Cugliandolo , D. R. Reichman , M. Sellitto

Pulse wave measurements provide vital information in medical diagnosis. For this reason, a measurement system is developed for determining the transient time of the pulse wave between the heart and the ear. To detect pressure variations in…

Medical Physics · Physics 2020-08-06 Roman Kusche , Paula Klimach , Ankit Malhotra , Steffen Kaufmann , Martin Ryschka

Spirals are common in Nature: the snail's shell and the ordering of seeds in the sunflower are amongst the most widely-known occurrences. While these are static, dynamic spirals can also be observed in excitable systems such as heart…

Dynamical Systems · Mathematics 2007-05-23 Patrick Boily

Left ventricular (LV) stiffness and contractility, characterized by the end-diastolic and end-systolic pressure-volume relationships (EDPVR & ESPVR), are two important indicators of the performance of the human heart. Although much research…

Medical Physics · Physics 2023-08-22 Yunxiao Zhang , Moritz Kalhöfer-Köchling , Eberhard Bodenschatz , Yong Wang

The influence of higher-order wavelet properties on the analytic wavelet transform behavior is investigated, and wavelet functions offering advantageous performance are identified. This is accomplished through detailed investigation of the…

Methodology · Statistics 2011-10-18 J. M. Lilly , S. C. Olhede

Cell signaling, gene expression, and metabolism are affected by cell-cell heterogeneity and random changes in the environment. The effects of such fluctuations on cell signaling and gene expression have recently been studied intensively…

Biological Physics · Physics 2015-04-02 A. -K. Gustavsson , C. B. Adiels , B. Mehlig , M. Goksör

Target waves and spiral waves were discovered in the Belousov-Zhabotinsky (BZ) reaction around 50 years ago. Many biological systems demonstrate such rotating spiral patterns. Spiral waves are widely encountered in the glycolytic activity…

Pattern Formation and Solitons · Physics 2024-09-27 Parvej Khan , Sumana Dutta

Amateur marathon runners who exercise excessively over time have pathological structural changes in their hearts and aortas. Amateur marathon runners' cardiovascular system adaptations and dangers are discussed in this article. After…

Other Quantitative Biology · Quantitative Biology 2025-07-16 Saeid Aghasoleymani Najafabadi , Hadi Jabbari Saray

Sex-based differences in cardiovascular disease are well documented, yet the precise nature and extent of these discrepancies in cardiac anatomy remain incompletely understood. Traditional scaling models often fail to capture the interplay…

Tissues and Organs · Quantitative Biology 2025-03-04 Beatrice Moscoloni , Cameron Beeche , Julio A. Chirinos , Patrick Segers , Mathias Peirlinck

Two mathematical methods, the Fourier and wavelet transforms, were used to study the short term cardiovascular control system. Time series, picked from electrocardiogram and arterial blood pressure lasting 6 minutes, were analyzed in supine…

Biological Physics · Physics 2009-11-10 Aiguo Xu , G. Gonnella , A. Federici , S. Stramaglia , F. Simone , A. Zenzola , R. Santostasi
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