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A computer model was developed for estimation of the kinetics of microbial inactivation by pulsed electric field. The model is based on the electroporation theory of individual membrane damage, where spherical cell geometry and distribution…

Biological Physics · Physics 2007-05-23 N. I. Lebovka , E. Vorobiev

The paper presents a computational stochastic model of virtual cells irradiation, based on Quasi-Markov Chain Monte Carlo method and using biophysical input. The model is based on a stochastic tree of probabilities for each cell of the…

Biological Physics · Physics 2014-12-23 Krzysztof Wojciech Fornalski

A methodology of calculations of survival curves with an account for ion paths interference is developed using the multiscale approach to the physics of radiation damage with ions. The method is applied to different targets and shouldered…

Medical Physics · Physics 2018-08-29 Eugene Surdutovich , Andrey V. Solov'yov

In our last paper, we have reported the direct interact between energetic ions and DNA, and its components, pointing out that damage to DNA is actually of highest biological consequence, as the integrity of DNA sequence is essential for…

Biological Physics · Physics 2008-07-02 Wei Wang , Zengliang Yu , Wenhui Su

In the present work, we investigate the ionization of molecules of biological interest by the impact of multicharged ions in the intermediate to high energy range. We performed full non-perturbative distorted-wave calculations (CDW) for…

Atomic and Molecular Clusters · Physics 2020-09-18 A. M. P. Mendez , C. C. Montanari , J. E. Miraglia

We study the time evolution of the wave function of a particle bound by an attractive $\delta$-function potential when it is subjected to time dependent variations of the binding strength (parametric excitation). The simplicity of this…

Mathematical Physics · Physics 2009-10-31 Alexander Rokhlenko , Joel L. Lebowitz

In previous work, we constructed a statistical framework for estimating the rate of clustered ionization from charged particle radiation in DNA. This model is extended to include contributions from secondary electrons. Using a simple…

Medical Physics · Physics 2023-11-17 Kay Kinoshita , Yusra Zabarmawi

It has long been known that radiation biology plays an important role and it is necessary for radiotherapy treatments. The radiation effects on normal and malignant tissues after exposure range from a femtosecond to months and years…

Medical Physics · Physics 2017-04-24 Cyril Voyant , Daniel Julian

In order to study the molecular damage induced in the form of single-strand and double-strand breaks by the ionizing radiation at the DNA level, Geant4-DNA Monte Carlo simulation code for complete transportation of primary protons and other…

Biological Physics · Physics 2018-10-10 Mojtaba Mokari , Mohammad Hassan Alamatsaz , Hossein Moeini , Reza Taleei

We propose an inclusive approach for calculating characteristics of secondary electrons produced by ions/protons in tissue-like media. This approach is based on an analysis of the projectile's interaction with the medium on the microscopic…

Biological Physics · Physics 2009-11-13 E. Surdutovich , O. I. Obolensky , E. Scifoni , I. Pshenichnov , I. Mishustin , A. V. Solov'yov , W. Greiner

We perform extensive 2D Particle-In-Cell (PIC) electromagnetic simulations of low pressure Inductively Coupled Plasma (ICP) discharges with various coil current and driving frequencies. Our simulations show that in low-frequency cases,…

The previously applied independent atom model (IAM) for highly charged ion-molecule collisions which implemented the suppression of multiple ionization and capture on the basis of geometric overlaps of cross-sectional areas representing…

Atomic Physics · Physics 2025-09-15 Hans Jürgen Lüdde , Marko Horbatsch , Tom Kirchner

The ion-electron coupling properties for a ion impurity in an electron gas and for a two component plasma are carried out on the basis of a regularized electron-ion potential removing the short-range Coulomb divergence. This work is largely…

Statistical Mechanics · Physics 2009-11-07 B Talin , E Dufour , A Calisti , M A Gigosos , M A Gonzalez , T del Rio Gaztelurrutia , J Dufty

We have studied the radiative decay of the 2s state of one-electron and one-muon ions, where the two-photon mechanism plays an important role. Due to the nuclear size corrections the radiative decay of the 2s state in the electron and muon…

Atomic Physics · Physics 2022-07-27 V. A. Knyazeva , K. N. Lyashchenko , M. Zhang , D. Yu , O. Yu. Andreev

To include the bound electron effects in particle-in-cell (PIC) simulation, we propose a model in which the response of the dipole components of partially ionized ions to external electromagnetic fields can be included. Instead of treating…

Plasma Physics · Physics 2022-08-18 Xiangyan An , Min Chen , Zheng-Ming Sheng , Jie Zhang

Joint electron-ion energy spectra for the dissociative ionization of a model H$_2^+$ in few-cycle, infrared laser pulses are calculated via the numerical ab initio solution of the time-dependent Schr\"odinger equation. A strong,…

Atomic Physics · Physics 2017-11-21 V. Mosert , D. Bauer

We extend the semiclassical two-step model for strong-field ionization that describes quantum interference and accounts for the Coulomb potential beyond the semiclassical perturbation theory to the hydrogen molecule. In the simplest case of…

Atomic Physics · Physics 2019-03-27 N. I. Shvetsov-Shilovski , M. Lein , K. Tőkési

The radiation-induced damages in bio-molecules are ubiquitous processes in radiotherapy, radio-biology and critical to space-projects. In this study we present a precise quantification of the fragmentation mechanisms of deoxyribonucleic…

Biological Physics · Physics 2022-01-28 Santosh KC , Ramin Abolfath

Ion-induced DNA damage is an important effect underlying ion-beam cancer therapy. This paper introduces the methodology of modeling DNA damage induced by a shock wave caused by a projectile ion. Specifically, it is demonstrated how single-…

Biological Physics · Physics 2021-07-09 Ida Friis , Alexey V. Verkhovtsev , Ilia A. Solov'yov , Andrey V. Solov'yov

We present an efficient method for modeling the single and double ionization dynamics of the H$_2$ molecule in ultrashort intense laser fields. This method is based on a semi-analytical approach to calculate the time-dependent single and…

Quantum Physics · Physics 2025-11-04 Jean-Nicolas Vigneau , Thanh-Tung Nguyen Dang , Eric Charron