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Related papers: Fluctuation-Driven Molecular Transport in an Asymm…

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We investigate transport through molecular wires whose energy levels are affected by environmental fluctuations. We assume that the relevant fluctuations are so slow that they, within a tight-binding description, can be described by…

Mesoscale and Nanoscale Physics · Physics 2008-07-09 Franz J. Kaiser , Peter Hänggi , Sigmund Kohler

Intracellular transport of vesicular cargos, organelles, and other macromolecules is an essential process to move large items through a crowded, and inhomogeneous cellular environment. In an effort to dissect the fundamental effects of…

Biomolecules · Quantitative Biology 2014-09-12 Leslie Conway , Jennifer L. Ross

There are a few obstacles, which bring about imperfect quantum teleportation of a continuous variable state, such as unavailability of maximally entangled two-mode squeezed states, inefficient detection and imperfect unitary transformation…

Quantum Physics · Physics 2009-11-06 M. S. Kim , Jinhyoung Lee

We study the diffusion of a tracer particle driven out-of-equilibrium by an external force and traveling in a dense environment of arbitrary density. The system evolves on a discrete lattice and its stochastic dynamics is described by a…

Statistical Mechanics · Physics 2018-05-23 Pierre Illien , Olivier Bénichou , Gleb Oshanin , Alessandro Sarracino , Raphaël Voituriez

Cells are complex structures which require considerable amounts of organization via transport of large intracellular cargo. While passive diffusion is often sufficiently fast for the transport of smaller cargo, active transport is necessary…

Biomolecules · Quantitative Biology 2018-08-29 Robert Blackwell , David Jung , Mona Bukenberger , Ana-Sunčana Smith

We consider model of a complex particle that consists of a rigid shell and a nucleus with spatial asymmetric interaction. The particle's dynamics with the nucleus driven by a periodic excitation is considered. It is shown that…

Chaotic Dynamics · Physics 2007-05-23 Sergey Denisov

It has been shown that the combination of a broken spatial symmetry in the potential (or ratchet potential) and time correlations in the driving are crucial, and enough to allow transformation of the fluctuations into work. The required…

Condensed Matter · Physics 2009-10-22 Dante R. Chialvo , Mark M. Millonas

We consider an inhomogeneous strongly correlated system where external disorder divides it into mesoscopic cells.Strong inter-particle repulsion suppresses the quantum tunneling between cells and open a wide temperature range for incoherent…

Strongly Correlated Electrons · Physics 2007-05-23 Darwin Chang , Dung-Hai Lee

We consider biochemical reaction chains and investigate how random external fluctuations, as characterized by variance and coefficient of variation, propagate down the chains. We perform such a study under the assumption that the number of…

Probability · Mathematics 2007-08-03 David F. Anderson , Jonathan C. Mattingly

Biologically driven non-equilibrium fluctuations are often characterized by their non-Gaussianity or by an "effective temperature", which is frequency dependent and higher than the ambient temperature. We address these two measures…

Biological Physics · Physics 2011-06-16 Eyal Ben-Isaac , YongKeun Park , Gabriel Popescu , Frank L. H. Brown , Nir S. Gov , Yair Shokef

Within cells, vesicles and proteins are actively transported several micrometers along the cytoskeletal filaments. The transport along microtubules is propelled by dynein and kinesin motors, which carry the cargo in opposite directions.…

Biological Physics · Physics 2020-05-20 Robin Jose , Ludger Santen

Aggregation and fragmentation of single molecules in the cell environment lead to a spectrum of diffusivities and to statistical laws of movement very different from typical Brownian motion. Current models of intracellular transport do not…

Statistical Mechanics · Physics 2020-07-08 M. Hidalgo-Soria , E. Barkai

Cell signaling, gene expression, and metabolism are affected by cell-cell heterogeneity and random changes in the environment. The effects of such fluctuations on cell signaling and gene expression have recently been studied intensively…

Biological Physics · Physics 2015-04-02 A. -K. Gustavsson , C. B. Adiels , B. Mehlig , M. Goksör

The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: a) traveling…

Biological Physics · Physics 2015-05-19 Anders E. Carlsson

Active cellular transport is a fundamental mechanism for protein and vesicle delivery, cell cycle and molecular degradation. Viruses can hijack the transport system and use it to reach the nucleus. Most transport processes consist of…

Quantitative Methods · Quantitative Biology 2009-11-13 T. Lagache , D. Holcman

Cells accomplish diverse functions using the same molecular building blocks, from setting up cytoplasmic flows to generating mechanical forces. In particular, transitions between these non-equilibrium states are triggered by regulating the…

Soft Condensed Matter · Physics 2022-01-03 Bibi Najma , Minu Varghese , Lev Tsidilkovski , Linnea Lemma , Aparna Baskaran , Guillaume Duclos

Water molecules play an important role in providing unique environments for biological reactions on cell membranes. It is widely believed that water molecules form bridges that connect lipid molecules and stabilize cell membranes. Using…

Biological Physics · Physics 2014-08-04 Eiji Yamamoto , Takuma Akimoto , Masato Yasui , Kenji Yasuoka

Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct…

Soft Condensed Matter · Physics 2012-09-05 Amit Kumar , Michael D. Graham

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

We propose a stochastic model for intracellular transport processes associated with the activity of molecular motors. This out-of-equilibrium model, based on a generalized Langevin equation, considers a particle immersed in a viscoelastic…

Biological Physics · Physics 2009-04-15 L. Bruno , M. A. Despósito