Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches
Biological Physics
2015-05-19 v1 Soft Condensed Matter
Subcellular Processes
Abstract
The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: a) traveling waves, b) moving patches, and c) random fluctuations. Increasing actin concentration causes a transition from patches to waves. The waves and patches move by a treadmilling mechanism which does not require myosin II. The effects of downregulation of key proteins on actin wave behavior are evaluated.
Keywords
Cite
@article{arxiv.1005.5314,
title = {Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches},
author = {Anders E. Carlsson},
journal= {arXiv preprint arXiv:1005.5314},
year = {2015}
}
Comments
10 pages, 4 figures