Branching, Capping, and Severing in Dynamic Actin Structures
Soft Condensed Matter
2009-11-13 v1 Cell Behavior
Abstract
Branched actin networks at the leading edge of a crawling cell evolve via protein-regulated processes such as polymerization, depolymerization, capping, branching, and severing. A formulation of these processes is presented and analyzed to study steady-state network morphology. In bulk, we identify several scaling regimes in severing and branching protein concentrations and find that the coupling between severing and branching is optimally exploited for conditions {\it in vivo}. Near the leading edge, we find qualitative agreement with the {\it in vivo} morphology.
Cite
@article{arxiv.cond-mat/0703409,
title = {Branching, Capping, and Severing in Dynamic Actin Structures},
author = {Ajay Gopinathan and Kun-Chun Lee and J. M. Schwarz and Andrea J. Liu},
journal= {arXiv preprint arXiv:cond-mat/0703409},
year = {2009}
}
Comments
4 pages, 2 figures