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The understanding of inactivation radiobiological mechanism in individual cells is important when from one side the application of ionizing radiation to tumour therapy and from the other side the protection against radiation are to be…

Biological Physics · Physics 2008-02-01 J. Barilla , M. Lokajíček , P. Simr

Electronic excitations and ionisations produced by electron impact are key processes in the radiation-induced damage mechanisms in materials of biological relevance, underlying important medical and technological applications, including…

Chemical Physics · Physics 2021-08-04 Pablo de Vera , Isabel Abril , Rafael Garcia-Molina

Ionizing radiation is known to delay the cell cycle progression. In particular after particle exposure significant delays have been observed and it has been shown that the extent of delay affects the expression of damage such as chromosome…

Cell Behavior · Quantitative Biology 2009-08-24 Anna Ochab-Marcinek , Ewa Gudowska-Nowak , Elena Nasonova , Sylvia Ritter

The paper presents a computational stochastic model of virtual cells irradiation, based on Quasi-Markov Chain Monte Carlo method and using biophysical input. The model is based on a stochastic tree of probabilities for each cell of the…

Biological Physics · Physics 2014-12-23 Krzysztof Wojciech Fornalski

It has long been known that radiation biology plays an important role and it is necessary for radiotherapy treatments. The radiation effects on normal and malignant tissues after exposure range from a femtosecond to months and years…

Medical Physics · Physics 2017-04-24 Cyril Voyant , Daniel Julian

By performing an ensemble of molecular dynamics simulations, the model-dependent ionisation state is computed for strongly interacting systems self-consistently. This is accomplished through a free energy minimisation framework based on the…

Photoionization of an atom in the presence of a neighboring atom of different species is studied. The latter first undergoes resonant photoexcitation, leading to an autoionizing state of the diatomic system. Afterwards, the excitation…

Atomic Physics · Physics 2020-08-11 F. Grüll , A. B. Voitkiv , C. Müller

We present a simple and general coherence model for multiorbital tunnel ionization of molecules, which we incorporate into our previously developed density matrix approach for sequential double ionization [Yuen and Lin, Phys. Rev. A 106,…

Atomic Physics · Physics 2023-09-07 C. H. Yuen , C. D. Lin

Double ionization of diatomic molecules by short linearly polarized laser pulses is analyzed. We consider the final stage of the ionization process, that is the decay of a highly excited two electron molecule, which is formed after…

Atomic Physics · Physics 2016-09-08 Jakub S. Prauzner-Bechcicki , Krzysztof Sacha , Bruno Eckhardt , Jakub Zakrzewski

Owing to its numerical simplicity, a two-dimensional two-electron model atom, with each electron moving in one direction, is an ideal system to study non-perturbatively a fully correlated atom exposed to a laser field. Frequently made…

Atomic Physics · Physics 2009-10-30 D. Bauer

We explore the laser-induced ionization dynamics of N2 and CO2 molecules subjected to a few-cycle, linearly polarized, 800\,nm laser pulse using effective two-dimensional single active electron time-dependent quantum simulations. We show…

Atomic Physics · Physics 2012-10-02 Michel Peters , Tung Nguyen-Dang , Eric Charron , Arne Keller , Osman Atabek

A discrete rate theory for general multi-ion channels is presented, in which the continuous dynamics of ion diffusion is reduced to transitions between Markovian discrete states. In an open channel, the ion permeation process involves three…

Biological Physics · Physics 2012-06-29 Wan Chen , Radek Erban , S. Jonathan Chapman

We first address the problem of initiation behind decaying shock waves analytically and numerically. The ignition along a particle path crossing the shock is analysed in terms of its volumetric expansion, evaluated as a function of the…

Fluid Dynamics · Physics 2022-11-11 Kevin Cheevers , Matei Radulescu

Numerical simulations are performed on a stochastic model based on Monte Carlo damage simulation process and Markov Chain Monte Carlo techniques to investigate the formation and evaluation of isolated and multiple DNA damage and cellular…

Quantitative Methods · Quantitative Biology 2019-11-20 M. Loan , B. Freeman , A. Bhat , M. Tantary , M. Brown , K. Virk

Radiation therapy is one of the most common cancer treatments, and dose optimization and targeting of radiation are crucial since both cancerous and healthy cells are affected. Different mathematical and computational approaches have been…

Biological Physics · Physics 2025-11-07 Mirko Bagnarol , Gianluca Lattanzi , Jan Åström , Mikko Karttunen

We give an explicit formula for the membrane potential of cells in terms of the intracellular and extracellular ionic concentrations, and derive equations for the ionic currents that flow through channels, exchangers and electrogenic pumps.…

Biological Physics · Physics 2007-05-23 L. P. Endresen , K. Hall , J. S. Hoye , J. Myrheim

We coincidently measure the molecular frame photoelectron angular distribution and the ion sum-momentum distribution of single and double ionization of CO molecules by using circularly and elliptically polarized femtosecond laser pulses,…

Atomic Physics · Physics 2015-06-04 J. Wu , L. Ph. H. Schmidt , M. Kunitski , M. Meckel , S. Voss , H. Sann , H. Kim , T. Jahnke , A. Czasch , R. Dörner

Interactions between biomolecules, electrons and protons are essential to many fundamental processes sustaining life. It is therefore of interest to build mathematical models of these bioelectrical processes not only to enhance…

Molecular Networks · Quantitative Biology 2020-12-08 Peter J. Gawthrop , Michael Pan

Joint electron-ion energy spectra for the dissociative ionization of a model H$_2^+$ in few-cycle, infrared laser pulses are calculated via the numerical ab initio solution of the time-dependent Schr\"odinger equation. A strong,…

Atomic Physics · Physics 2017-11-21 V. Mosert , D. Bauer

Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez