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Related papers: A steepest descent calculation of RNA pseudoknots

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Automatically determining knot number and positions is a fundamental and challenging problem in B-spline approximation. In this paper, the knot placement is abstracted as a mapping from initial knots to the optimal knots. We innovatively…

Optimization and Control · Mathematics 2024-03-19 Jiaqi Luo , Zepeng Wen , Hongmei Kang , Zhouwang Yang

Pseudospectral analysis serves as a powerful tool in matrix computation and the study of both linear and nonlinear dynamical systems. Among various numerical strategies, random sampling, especially in the form of rank-$1$ perturbations,…

Spectral Theory · Mathematics 2025-05-19 Kuo Gai , Bin Shi

In this paper we study irreducibility in RNA structures. By RNA structure we mean RNA secondary as well as RNA pseudoknot structures. In our analysis we shall contrast random and minimum free energy (mfe) configurations. We compute various…

Biomolecules · Quantitative Biology 2009-02-24 Emma Y. Jin , Christian M. Reidys

Investigations of molecular bonds between single molecules and molecular complexes by the dynamic force spectroscopy are subject to large fluctuations at nanoscale and possible other aspecific binding, which mask the experimental output.…

Molecular Networks · Quantitative Biology 2015-05-14 Jelena Zivković , Marija Mitrović , Luuk Janssen , Hans A. Heus , Bosiljka Tadić , Sylvia Speller

We compute the lowest moments of the nucleon's structure functions using quenched overlap fermions at two different lattice spacings. The renormalisation is done nonperturbatively in the RI'-MOM-scheme.

High Energy Physics - Lattice · Physics 2008-11-26 D. Galletly , M. Gürtler , R. Horsley , K. Koller , V. Linke , P. E. L. Rakow , C. J. Roberts , G. Schierholz , T. Streuer

Widely used closed product-form networks have emerged recently as a primary model of stochastic growth of sub-cellular structures, e.g., cellular filaments. In the baseline model, homogeneous monomers attach and detach stochastically to…

Probability · Mathematics 2020-07-30 Predrag Jelenkovic , Jane Kondev , Lishibanya Mohapatra , Petar Momcilovic

We conclude our analysis of bubble divergences in the flat spinfoam model. In [arXiv:1008.1476] we showed that the divergence degree of an arbitrary two-complex Gamma can be evaluated exactly by means of twisted cohomology. Here, we…

General Relativity and Quantum Cosmology · Physics 2012-02-03 Valentin Bonzom , Matteo Smerlak

For solving pseudo-convex global optimization problems, we present a novel fully adaptive steepest descent method (or ASDM) without any hard-to-estimate parameters. For the step-size regulation in an $\varepsilon$-normalized direction, we…

Optimization and Control · Mathematics 2021-08-12 Z. R. Gabidullina

The history and importance of superdeformation in nuclei is briefly discussed. A simple two-level model is then employed to obtain an elegant expression for the branching ratio for the decay via the E1 process in the normal-deformed band of…

Nuclear Theory · Physics 2009-11-11 B. R. Barrett , D. M. Cardamone , C. A. Stafford

The prevalent method for RNA secondary structure prediction for a single sequence is free energy minimization based on the nearest neighbor thermodynamic model (NNTM). One of the least well-developed parts of the model is the energy…

Biomolecules · Quantitative Biology 2017-08-21 Fidel Barrera-Cruz , Christine Heitsch , Svetlana Poznanović

Deep neural networks are powerful learning models that achieve state-of-the-art performance on many computer vision, speech, and language processing tasks. In this paper, we study a fundamental question that arises when designing deep…

Machine Learning · Statistics 2017-10-24 Shiva Prasad Kasiviswanathan , Nina Narodytska , Hongxia Jin

Fluid-structure interaction models are used to study how a material interacts with different fluids at different Reynolds numbers. Examining the same model not only for different fluids but also for different solids allows to optimize the…

Numerical Analysis · Mathematics 2023-07-28 Peter Benner , Thomas Richter , Roman Weinhandl

The design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which can tremendously impact their cost and…

Quantitative Methods · Quantitative Biology 2018-06-24 Stefan Hammer , Yann Ponty , Wei Wang , Sebastian Will

Branched junction molecule assembly of DNA nanostructures, pioneered by Seeman's laboratory in the 1980s, has become increasingly sophisticated, as have the assembly targets. A critical design step is finding minimal sets of branched…

Combinatorics · Mathematics 2021-08-03 Leyda Almodóvar , Jo Ellis-Monaghan , Amanda Harsy , Cory Johnson , Jessica Sorrells

The interacting shell model, a configuration-interaction method, is a venerable approach for low-lying nuclear structure calculations; but it is hampered by the exponential growth of its basis dimension as one increases the single-particle…

Nuclear Theory · Physics 2024-09-05 Oliver C. Gorton , Calvin W. Johnson

Small subgraph counts can be used as summary statistics for large random graphs. We use the Stein-Chen method to derive Poisson approximations for the distribution of the number of subgraphs in the stochastic block model which are…

Probability · Mathematics 2017-03-21 Matthew Coulson , Robert E. Gaunt , Gesine Reinert

The eigenvalue structure of the quantum transfer matrix is known to encode essential information about the elementary excitations. Here we study transfer matrices of quantum states in a topological phase using the tensor network formalism.…

Strongly Correlated Electrons · Physics 2016-07-26 Jutho Haegeman , Valentin Zauner , Norbert Schuch , Frank Verstraete

We use the steepest descents method to study the integral kernel of a family of normal random matrix ensembles with eigenvalue distribution P_{N}(z_{1},...,z_{N}) = Z_{N}^{-1} e^{-N\Sigma_{i=1}^{N}V_{\alpha}(z_{i})}…

Mathematical Physics · Physics 2015-05-28 Alexei M. Veneziani , Tiago Pereira , Domingos H. U. Marchetti

Background: RNA exhibits a variety of structural configurations. Here we consider a structure to be tantamount to the noncrossing Watson-Crick and \pairGU-base pairings (secondary structure) and additional cross-serial base pairs. These…

Combinatorics · Mathematics 2010-03-11 James Z. M. Gao , Linda Y. M. Li , Christian M. Reidys

Tensor network contraction is a fundamental mathematical operation that generalizes the dot product and matrix multiplication. It finds applications in numerous domains, such as database systems, graph theory, machine learning, probability…

Data Structures and Algorithms · Computer Science 2026-03-10 Mike Heddes , Igor Nunes , Tony Givargis , Alex Nicolau