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The paper, drawing on the example of simulation codes used in nuclear physics and high-energy physics, seeks to highlight the ethical implications of discontinuing support for simulation codes and the loss of knowledge embodied in them.…

History and Philosophy of Physics · Physics 2020-11-26 Vitaly Pronskikh

In sexual population, recombination reshuffles genetic variation and produces novel combinations of existing alleles, while selection amplifies the fittest genotypes in the population. If recombination is more rapid than selection,…

Populations and Evolution · Quantitative Biology 2015-06-05 Richard A. Neher , Marija Vucelja , Marc Mézard , Boris I. Shraiman

In a population with haploid reproduction any individual has a single parent in the previous generation. If all genealogical distances among pairs of individuals (generations from the closest common ancestor) are known it is possible to…

Populations and Evolution · Quantitative Biology 2015-05-13 Luce Prignano , Maurizio Serva

The sampling of interaction partners depends on often implicit modelling assumptions, yet has marked effects on the dynamics in evolutionary games. One particularly important aspect is whether or not competitors also interact. Population…

Populations and Evolution · Quantitative Biology 2018-11-20 Christoph Hauert , Jacek Miȩkisz

Genome-wide association studies, in which as many as a million single nucleotide polymorphisms (SNP) are measured on several thousand samples, are quickly becoming a common type of study for identifying genetic factors associated with many…

Methodology · Statistics 2010-10-25 Charles Kooperberg , Michael LeBlanc , James Y. Dai , Indika Rajapakse

The BIOSCAN project, led by the International Barcode of Life Consortium, seeks to study changes in biodiversity on a global scale. One component of the project is focused on studying the species interaction and dynamics of all insects. In…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Nicholas Pellegrino , Zahra Gharaee , Paul Fieguth

We show that textual analysis of microbial genomes reveal telling footprints of the early evolution of the genomes. The frequencies of word occurrence of random DNA sequences considered as texts in their four nucleotides are expected to…

Biological Physics · Physics 2007-05-23 Li-Ching Hsieh , Liaofu Luo , HC Lee

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

Evolutionary theorizing resembles building an aircraft while also piloting it; new results change the scaffold for older ideas, requiring revised strategy to remain airborne. A calculated kinetic pathway exists that, under explicit…

Populations and Evolution · Quantitative Biology 2024-10-11 Michael Yarus

Real networks exhibit heterogeneous nature with nodes playing far different roles in structure and function. To identify vital nodes is thus very significant, allowing us to control the outbreak of epidemics, to conduct advertisements for…

Physics and Society · Physics 2016-09-21 Linyuan Lü , Duanbing Chen , Xiao-Long Ren , Qian-Ming Zhang , Yi-Cheng Zhang , Tao Zhou

Many complex networks exhibit a percolation transition involving a macroscopic connected component, with universal features largely independent of the microscopic model and the macroscopic domain geometry. In contrast, we show that the…

Disordered Systems and Neural Networks · Physics 2017-06-29 Justin Coon , Carl P. Dettmann , Orestis Georgiou

We introduce a biologically natural, mathematically tractable model of random phylogenetic network to describe evolution in the presence of hybridization. One of the features of this model is that the hybridization rate of the lineages…

Probability · Mathematics 2024-02-27 François Bienvenu , Jean-Jil Duchamps

The universal genetic code presents a fundamental paradox in molecular biology. Recent advances in synthetic biology have demonstrated that the code is remarkably flexible--organisms can survive with 61 codons instead of 64, natural…

Populations and Evolution · Quantitative Biology 2025-07-03 Marc Bara Iniesta

Our view of the microbial world and its impact on human health is changing radically with the ability to sequence uncultured or unculturable microbes sampled directly from their habitats, ability made possible by fast and cheap next…

Quantitative Methods · Quantitative Biology 2013-05-13 Edi Prifti , Jean-Daniel Zucker

We discuss a model of genome as a program with functional architecture and consider the approach to Darwinian evolution as a learning problem for functional programming. In particular we introduce a model of learning for some class of…

Neural and Evolutionary Computing · Computer Science 2020-06-18 S. V. Kozyrev

Rare events have played an increasing role in molecular phylogenetics as potentially homoplasy-poor characters.In this contribution we analyze the phylogenetic information content from a combinatorial point of view by consid-ering the…

Discrete Mathematics · Computer Science 2017-06-15 Marc Hellmuth , Maribel Hernandez-Rosales , Yangjing Long , Peter F. Stadler

Portable genome sequencing technology is revolutionizing genomic research by providing a faster, more flexible method of sequencing DNA and RNA [1, 2]. The unprecedented shift from bulky stand-alone benchtop equipment confined in a…

Cryptography and Security · Computer Science 2024-07-18 Carson Stillman , Jonathan E. Bravo , Christina Boucher , Sara Rampazzi

To study potential limitations of controllability of physical systems I have earlier proposed physically universal cellular automata and Hamiltonians. These are translation invariant interactions for which any control operation on a finite…

Quantum Physics · Physics 2018-04-18 Dominik Janzing

A qualitative discussion on the range of the potentials as they result from the phenomenological meson-exchange picture and from lattice simulations by the HAL QCD Collaboration is presented. For the former pion- and/or $\eta$-meson…

Nuclear Theory · Physics 2019-06-05 J. Haidenbauer , U. -G. Meißner

It has been repeatedly proposed to expand the scope for SETI, and one of the suggested alternatives to radio is the biological media. Genomic DNA is already used on Earth to store non-biological information. Though smaller in capacity, but…

Other Quantitative Biology · Quantitative Biology 2017-06-13 Vladimir I. shCherbak , Maxim A. Makukov
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