Related papers: Design of the MPRI Control System
We present a method for optimization of the multi-turn injection effciency for medical synchrotron. We show that for given injection energy the injection efficiency can be greatly enhanced by choosing transverse tunes appropriately as well…
The current and future need for high-energy neutrons has been a subject of increasing discussion and concern. Immediate applications for such an intense neutron source include medical isotope production, high-energy physics (HEP) research,…
Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several indications has yielded improved prognosis for cases where traditional therapy has shown limited efficiencey. However, many patients still fail to…
Advanced radiotherapy approaches such as FLASH irradiation and spatially fractionated radiotherapy (SFRT) show potential to improve the therapeutic ratio, yet their biological mechanisms and optimal delivery parameters remain uncertain.…
A new prototype of STAR inner Time Projection Chamber (iTPC) MWPC sector has been fabricated and tested in an X-ray test system. The wire chamber built at Shandong University has a wire tension precision better than 6$\%$ and wire pitch…
In particle therapy with protons a cyclotron is one of the most used particle accelerators. Here it will be explained how a cyclotron works, some beam dynamics aspects, its major subsystems, as well as the advantages and disadvantages of a…
A high-performance time-of-flight (TOF) MRPC wall is being built for the CBM experiment at FAIR for charged hadron identification. The detector control system for the TOF system will be based on EPICS. All components like power supplies for…
Plasma processing has been shown to help mitigate degradation of the performance of superconducting radio-frequency cavities, providing an alternative to removal of cryomodules from the accelerator for refurbishment. Studies of plasma…
The Fermilab accelerator complex delivers intense high-energy proton beams to a variety of fixed-target scientific programs, including a flagship long-baseline neutrino program. With the advent of the Deep Underground Neutrino Experiment…
Recent advancements in smart radio environment technologies aim to enhance wireless network performance through the use of low-cost electromagnetic (EM) devices. Among these, reconfigurable intelligent surfaces (RIS) have garnered attention…
To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…
Electron beam stabilization in a synchrotron is a disturbance rejection problem, with hundreds of inputs and outputs, that is sampled at frequencies higher than $10$ kHz. In this feasibility study, we focus on the practical issues of an…
The proton irradiation accelerator is widely founded for industry application, and should be designed as compact, reliable, and easy operate. A 10 MeV proton beam is designed to be injected into the slow circulation ring with the repetition…
Faster, cheaper, and more power efficient optimization solvers than those currently offered by general-purpose solutions are required for extending the use of model predictive control (MPC) to resource-constrained embedded platforms. We…
A multi-MW proton facility, Project X has been proposed and is currently under development at Fermilab. As part of this development program, we are constructing a prototype of the front end of the Project X linac at Fermilab. The…
The strategy used to develop the NIF Integrated Computer Control System (ICCS) calls for incremental cycles of construction and formal test to deliver a total of 1 million lines of code. Each incremental release takes four to six months to…
Technetium-99m ($^{99m}$Tc) is essential to more than 16 million diagnostic procedures performed annually in the United States. It is typically acquired on-site from generators containing $^{99}$Mo, in turn produced at nuclear reactor…
Automatic diagnosis of malignant prostate cancer patients from mpMRI has been studied heavily in the past years. Model interpretation and domain drift have been the main road blocks for clinical utilization. As an extension from our…
The demand of transparency of clinical research results, the need of accelerating the process of transferring innovation in the daily medical practice as well as assuring patient safety and product efficacy make it necessary to extend the…
We propose a novel Phase I intra-patient dose-escalation design tailored for multi-cycle immunotherapy settings, in which toxicity at a fixed dose level is clinically expected to decrease over successive treatment cycles. This design was…