Related papers: Tumour Therapy with Particle Beams
Ionization is one of the basic physical processes, occurring when charged particles penetrate atomic matter. When atoms are bombarded by very dense and compact beams of extreme relativistic electrons, two qualitatively new -- and very…
Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deliver a highly conformal dose to the tumor while sparing…
Producing a dense background plasma for neutralization purposes is experimentally difficult and requires a large amount of energy. We show that even an underdense background plasma with a small relative density can achieve high…
In the past two decades, laser-accelerated ion sources and their applications have been intensely researched. Recently, it has been shown through experiments that proton beams with characteristics comparable to those obtained with solid…
A plethora of studies ranging from precision physics to quantum information employ ions, highly excited neutral atoms or polar molecules as tools. Motivated by the need for miniaturization, scalability and controllability, the particles are…
A work recently published experimentally demonstrates an increase in the radiobiological efficacy of clinical proton beams when a tumour is treated in the presence of a concentration of 11B. The paper, for the first time, demonstrates the…
Laser-driven ion acceleration provides ultra-short, high-charge, low-emittance beams, which are desirable for a wide range of high-impact applications. Yet after decades of research, a significant increase in maximum ion energy is still…
Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…
The design, construction, and preliminary testing of a second generation proton CT scanner is presented. All current treatment planning systems at proton therapy centers use X-ray CT as the primary imaging modality for treatment planning to…
Laser-driven ion acceleration is an attractive technique for compact high-energy ion sources. Currently, among various physical and technical issues to be solved, the boost of ion energy and the reduction of energy spread represent the key…
Imaging of nuclear gamma-ray lines in the 1-10 MeV range is far from being established in both medical and physical applications. In proton therapy, 4.4 MeV gamma rays are emitted from the excited nucleus of either 12^C^* or 11^B^* and are…
We show that atoms subject to laser radiation may form a non-additive many-body system on account of their long-range forces, when the atoms are trapped in the vicinity of a fiber with a Bragg grating. When the laser frequency is inside the…
The maximum energy loss (Bragg peak) located near the end of range is a characteristic feature of ion stopping in matter, which generates an acoustic pulse, if ions are deposited into a medium in adequately short bunches. This so-called…
Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…
It was recently discovered that molecular ionization at high x-ray intensity is enhanced, in comparison with that of isolated atoms, through a phenomenon called CREXIM (charge-rearrangement-enhanced x-ray ionization of molecules). X-ray…
Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…
By integrating tweezer arrays with a high-cooperativity ring cavity with chiral atom-cavity coupling, we demonstrate highly directional Bragg scattering from a programmable number of atoms. Through accurate control of the interatomic…
The major advantage of proton therapy over conventional radiotherapy is the dose deposition pattern, enabling precise coverage of the tumour volume while sparing nearby healthy tissues. However, accurate control of the proton beam range…
Non-invasive optical manipulation of particles has emerged as a powerful and versatile tool for biological study and nanotechnology. In particular, trapping and rotation of cells, cell nuclei and sub-micron particles enables unique…
We clarify how intense laser irradiation leads to an enhancement of rare processes that may occur within atoms. Non-perturbative calculation using a coherent laser beam gives an exact, time dependent formula of the enhancement factor in the…