Related papers: Tumour Therapy with Particle Beams
Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…
The purpose of this study is to determine whether organ sparing and target coverage can be simultaneously maintained for pencil beam scanning (PBS) proton therapy treatment of thoracic tumors in the presence of motion, stopping power…
Spin squeezing in atomic ensembles enables atom interferometry with sensitivities below the shot-noise limit, but the associated entanglement is highly susceptible to loss, making imperfections in atom optics a central limitation. Bragg…
This study aims to assess the composition of scattered particles generated in proton therapy for tumours situated proximal to titanium dental implants. The investigation involves decomposing the mixed field and recording Linear Energy…
Extending the Kruppa's prescription for the continuum level density, we have recently improved the BCS method with seniority-type pairing force in such a way that the effects of discretized unbound states are properly taken into account for…
Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…
Depolarization of circularly polarized light scattered from biological tissues depends on structural changes in cell nuclei, which can provide valuable information for differentiating cancer tissues concealed in healthy tissues. In this…
Proton acceleration by using a 620-TW, 18-J laser pulse of peak intensity of $5\times 10^{21}$ W/cm$^{2}$ irradiating a disk target is examined using three-dimensional particle-in-cell simulations. It is shown that protons are accelerated…
An optical injection scheme into the laser wakefield accelerator by preceding injection pulse is investigated by means of 3D numerical particle-in-cell simulations. Quasimonoenergetic hundred-pC electron bunches as short as 6 fs can be…
A new regime is described for Radiation Pressure Acceleration of a thin foil by an intense laser beam of above 10^20 W/cm^2. Highly monoenergetic proton beams extending to GeV energies can be produced with very high efficiency using…
A relativistic light front treatment of nuclei is developed by performing light front quantization for a chiral Lagrangian. The energy momentum tensor and the appropriate Hamiltonian are obtained. Three illustrations of the formalism are…
The production of polarized proton beams with multi-GeV energies in ultra-intense laser interaction with targets is studied with three-dimensional Particle-In-Cell simulations. A near-critical density plasma target with pre-polarized proton…
We give a scenario-based treatment plan optimization formulation that is equivalent to planning with geometric margins if the scenario doses are calculated using the static dose cloud approximation. If the scenario doses are instead…
Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…
Grade II gliomas are slowly growing primary brain tumors that affect mostly young patients and become fatal after a few years. Current clinical handling includes surgery as first line treatment. Cytotoxic therapies (radiotherapy RT or…
230 MeV proton beam out of a cyclotron was delivered into a Zebra multi layered IC detector (IBA) calibrated in terms of penetration range in water. The analysis of the measured Bragg peak determines penetration range in water which can be…
Due to its ubiquitous presence, turbulence is often invoked to explain the origin of nonthermal particles in astrophysical sources of high-energy emission. With particle-in-cell simulations, we study decaying turbulence in…
Background and purpose: IMPT faces challenges in lung cancer treatment, like maintaining plan robustness for moving tumors against setup, range errors, and interplay effects. Proton Arc Therapy (PAT) is an alternative to maintain target…
The partial-wave expansion used to treat the distortion of scattered electrons by the nuclear Coulomb field is simpler and considerably less time-consuming when applied to the production of muons and electrons by low and intermediate-energy…
A new scheme of proton acceleration from a laser-driven near-critical-density plasma is proposed. Plasma with a tailored density profile allows a two-stage acceleration of protons. The protons are pre-accelerated in the laser-driven…