Related papers: Using dimension reduction to improve outbreak pred…
Multi-strain diseases are diseases that consist of several strains, or serotypes. The serotypes may interact by antibody-dependent enhancement (ADE), in which infection with a single serotype is asymptomatic, but infection with a second…
In this study, we develop and analyze a deterministic two-strain host-vector model for dengue transmission that incorporates key immuno-epidemiological mechanisms, including temporary cross-immunity, antibody-dependent enhancement (ADE),…
A new method is proposed to infer unobserved epidemic sub-populations by exploiting the synchronization properties of multistrain epidemic models. A model for dengue fever is driven by simulated data from secondary infective populations.…
This paper examines the interplay of the effect of cross immunity and antibody-dependent enhancement (ADE) in mutistrain diseases. Motivated by dengue fever, we study a model for the spreading of epidemics in a population with multistrain…
We analyse an epidemiological model of competing strains of pathogens and hence differences in transmission for first versus secondary infection due to interaction of the strains with previously aquired immunities, as has been described for…
Infection by distinct Dengue virus serotypes and host immunity are intricately linked. In particular, certain levels of cross-reactive antibodies in the host may actually enhance infection severity leading to Dengue hemorrhagic fever (DHF).…
An epidemic multi-strain model with temporary cross-immunity shows chaos, even in a previously unexpected parameter region. Especially dengue fever models with strong enhanced infectivity on secondary infection have previously shown…
Different extensions of the classical single-strain SIR model for the host population, motivated by modeling dengue fever epidemiology, have reported a rich dynamic structure including deterministic chaos which was able to explain the large…
Dengue is a vector-borne viral disease increasing dramatically over the past years due to improvement in human mobility. The movement of host individuals between and within the patches are captured via a residence-time matrix. A system of…
Dengue viral infections show unique infection patterns arising from its four serot- ypes, (DENV-1,2,3,4). Its effects range from simple fever in primary infections to potentially fatal secondary infections. We analytically and numerically…
Many infectious diseases are comprised of multiple strains with examples including Influenza, tuberculosis, and Dengue virus. The time evolution of such systems is linked to a complex landscape shaped by interactions between competing…
Dengue is a vector borne disease transmitted to humans by {\it{Aedes Aegypti}} mosquitoes carrying Dengue virus of different serotypes. Primarily an urban epidemic, Dengue exhibits complex spatial and temporal dynamics, influenced by many…
We propose an SEIR model for the populations and an SEI model for the vector to describe the transmission dynamics of a four-strain model with both primary and secondary dengue infections. In order to accomplish this, we propose and obtain…
Dengue fever is a flu-like illness spread by the bite of an infected mosquito which is fast emerging as a major health problem. Timely and cost effective diagnosis using clinical and laboratory features would reduce the mortality rates…
We use a stochastic Markovian dynamics approach to describe the spreading of vector-transmitted diseases, like dengue, and the threshold of the disease. The coexistence space is composed by two structures representing the human and mosquito…
Traditional biomedical approaches treat diseases in isolation, but the importance of synergistic disease interactions is now recognized. As a first step we present and analyze a simple coinfection model for two diseases affecting…
Antibodies play an essential role in the immune response to viral infections, vaccination, or antibody therapy. Nevertheless, they can be either protective or harmful during the immune response. Moreover, competition or cooperation between…
Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…
Developments in dynamical systems theory provides new support for the macroscale modelling of pdes and other microscale systems such as Lattice Boltzmann, Monte Carlo or Molecular Dynamics simulators. By systematically resolving subgrid…
During the last decades, the global prevalence of dengue progressed dramatically. It is a disease that is now endemic in more than one hundred countries of Africa, America, Asia, and the Western Pacific. In this paper, we present a…