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This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

Dengue and Zika incidence data and the latest research have raised questions about how dengue vaccine strategies might be impacted by the emergence of Zika virus. Existing antibodies to one virus might temporarily protect or promote…

Populations and Evolution · Quantitative Biology 2023-03-14 Lorena C. Bulhosa , Juliane F. Oliveira

Current modeling of infectious diseases allows for the study of complex and realistic scenarios that go from the population to the individual level of description. However, most epidemic models assume that the spreading process takes place…

Physics and Society · Physics 2015-04-15 Joaquín Sanz , Cheng-Yi Xia , Sandro Meloni , Yamir Moreno

Disease progression modeling provides a robust framework to identify long-term disease trajectories from short-term biomarker data. It is a valuable tool to gain a deeper understanding of diseases with a long disease trajectory, such as…

Dengue is a vector borne infectious disease. The disease is transmitted byAedes mosquitoes. In the present work, SEIR - SEI compartmental epidemiological model is used to describe dengue disease transmission dynamics. The human population…

Populations and Evolution · Quantitative Biology 2025-01-30 Ganga Ram Phaijoo , Dil Bahadur Gurung

Dynamic properties of spreading infection through a heterogeneous population are studied numerically and analytically using a dynamic variant of Watts and Strogatz Small World Network-based stochastic Susceptible-Exposed-Infectious-Removed…

Populations and Evolution · Quantitative Biology 2019-06-28 O. Mosbah , N. Zekri , M. Mokhtari , S. Sahraoui

Wearable sensor technologies and deep learning are transforming healthcare management. Yet, most health sensing studies focus narrowly on physical chronic diseases. This overlooks the critical need for joint assessment of comorbid physical…

Machine Learning · Computer Science 2025-11-21 Yidong Chai , Haoxin Liu , Jiaheng Xie , Chaopeng Wang , Xiao Fang

There is a growing proportion of people with several disease conditions ("multimorbidity"), placing increasing demands on healthcare systems. One hypothesis is that clusters of diseases may arise from shared underlying disease processes…

Methodology · Statistics 2025-08-15 Anthony J. Webster

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

Mathematical disease modelling has long operated under the assumption that any one infectious disease is caused by one transmissible pathogen spreading among a population. This paradigm has been useful in simplifying the biological reality…

Populations and Evolution · Quantitative Biology 2021-06-02 Blake J. M. Williams , Guillaume St-Onge , Laurent Hébert-Dufresne

We consider a class of models describing an ensemble of identical interacting agents subject to multiplicative noise. In the thermodynamic limit, these systems exhibit continuous and discontinuous phase transitions in a, generally,…

Statistical Mechanics · Physics 2023-10-27 Niccolò Zagli , Grigorios A. Pavliotis , Valerio Lucarini , Alexander Alecio

Disease spreading models such as the ubiquitous SIS compartmental model and its numerous variants are widely used to understand and predict the behaviour of a given epidemic or information diffusion process. A common approach to imbue more…

Dynamical Systems · Mathematics 2025-11-18 Eugene Tan , Michael Small , Shannon D. Algar

During the last decades, the global prevalence of dengue progressed dramatically. It is a disease which is now endemic in more than one hundred countries of Africa, America, Asia and the Western Pacific. This study addresses a mathematical…

We introduce a dengue model (SEIR) where the human individuals are treated on an individual basis (IBM) while the mosquito population, produced by an independent model, is treated by compartments (SEI). We study the spread of epidemics by…

Populations and Evolution · Quantitative Biology 2015-03-17 Marcelo J Otero , Daniel H Barmak , Claudio O Dorso , Hernán G Solari , Mario A Natiello

The resurgence of vector-borne diseases is an increasing public health concern, and there is a need for a better understanding of their dynamics. For a number of diseases, e.g. dengue and chikungunya, this resurgence occurs mostly in urban…

Populations and Evolution · Quantitative Biology 2017-04-14 Abderrahman Iggidr , Gauthier Sallet , Max O. Souza

The transmission of vector infectious diseases, which produces complex spatiotemporal patterns, is analyzed by a periodically forced two-dimensional cellular automata model. The system, which comprises three population levels, is introduced…

Cellular Automata and Lattice Gases · Physics 2008-10-03 L. B. L. Santos , M. C. Costa , S. T. R. Pinho , R. F. S. Andrade , F. R. Barreto , M. G. Teixeira , M. L. Barreto

Pairwise models are used widely to model epidemic spread on networks. These include the modelling of susceptible-infected-removed (SIR) epidemics on regular networks and extensions to SIS dynamics and contact tracing on more exotic networks…

Populations and Evolution · Quantitative Biology 2018-09-24 István Z. Kiss , Joel C. Miller , Péter L. Simon

Developments in dynamical systems theory provides new support for the discretisation of \pde{}s and other microscale systems. By systematically resolving subgrid microscale dynamics the new approach constructs asymptotically accurate,…

Numerical Analysis · Mathematics 2009-04-07 Tony MacKenzie , A. J. Roberts

Disease awareness in infection dynamics can be modeled with adaptive contact networks whose rewiring rules reflect the attempt by susceptibles to avoid infectious contacts. Simulations of this type of models show an active phase with…

Adaptation and Self-Organizing Systems · Physics 2012-12-06 Stefan Wieland , Tomas Aquino , Ana Nunes

Epidemiological models may give some basic guidelines for public health practitioners, allowing to analyze issues that can influence the strategies to prevent and fight a disease. To be used in decision-making, however, a mathematical model…

Populations and Evolution · Quantitative Biology 2013-08-15 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres