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The goal of this paper is to propose a new mathematical model for the combined effect of different treatments and lifestyles on the glucose-insulin dynamics of Type 2 diabetes (T2D) patients. The model gives the possibility to take into…

Systems and Control · Electrical Eng. & Systems 2023-01-11 Mohamad Al Ahdab , John Leth , Torben Knudsen , Peter Vestergaard , Henrik Clausen

This paper considers the modeling of zero-inflated circular measurements concerning real case studies from medical sciences. Circular-circular regression models have been discussed in the statistical literature and illustrated with various…

Methodology · Statistics 2022-01-04 Jayant Jha , Prajamitra Bhuyan

Caliper matching is used to estimate causal effects of a binary treatment from observational data by comparing matched treated and control units. Units are matched when their propensity scores, the conditional probability of receiving…

Statistics Theory · Mathematics 2023-04-18 Máté Kormos , Stéphanie van der Pas , Aad van der Vaart

The steady-state current-voltage response of ion-selective systems varies as the number of ion-selective components is varied. For the highly investigated unipolar system, including only one ion-selective component, it has been shown that…

Mesoscale and Nanoscale Physics · Physics 2024-11-27 Ramadan Abu-Rjal , Yoav Green

Models of coupled oscillators are used to describe a wide variety of phenomena in neuroimaging. These models typically rest on the premise that oscillator dynamics do not evolve beyond their respective limit cycles, and hence that…

Quantitative Methods · Quantitative Biology 2019-09-19 Erik D. Fagerholm , Rosalyn J. Moran , Ines R. Violante , Robert Leech , Karl J. Friston

Periodic hematological diseases such as cyclical neutropenia or cyclical thrombocytopenia, with their characteristic oscillations of circulating neutrophils or platelets, may pose grave problems for patients. Likewise, periodically…

Dynamical Systems · Mathematics 2019-04-17 Daniel C. De Souza , Michael C. Mackey

Several nonlinear and nonequilibrium driven as well as active systems (e.g. microswimmers) show bifurcations from one state to another (for example a transition from a non motile to motile state for microswimmers) when some control…

Soft Condensed Matter · Physics 2022-01-10 Alexander Farutin , Chaouqi Misbah

We developed a nonlinear differential equation model to explore the dynamics of relapse phenomena. Our incidence rate function is formulated, taking inspiration from recent adaptive algorithms. It incorporates contact behavior for…

Dynamical Systems · Mathematics 2023-06-27 Jimmy Calvo-Monge , Fabio Sanchez , Juan G. Calvo , Darío Mena

The activity of collections of synchronizing neurons can be represented by weakly coupled nonlinear phase oscillators satisfying Kuramoto's equations. In this article, we build such neural-oscillator models, partly based on…

Neurons and Cognition · Quantitative Biology 2012-04-27 Patrick Suppes , Jose Acacio de Barros , Gary Oas

This work concerns a many-body deterministic model that displays life-like properties as emergence, complexity, self-organization, spontaneous compartmentalization, and self-regulation. The model portraits the dynamics of an ensemble of…

Adaptation and Self-Organizing Systems · Physics 2023-07-11 Alessandro Scirè , Valerio Annovazzi-Lodi

Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic…

We consider multi-class systems of interacting nonlinear Hawkes processes modeling several large families of neurons and study their mean field limits. As the total number of neurons goes to infinity we prove that the evolution within each…

Probability · Mathematics 2016-10-04 Susanne Ditlevsen , Eva Löcherbach

We rigorously show that a class of systems of partial differential equations modeling wave bifurcations supports stationary equivariant bifurcation dynamics through deriving its full dynamics on the center manifold(s). A direct consequence…

Analysis of PDEs · Mathematics 2015-06-09 Tong Li , Xiaoyan Wang , Jinghua Yao

We demonstrate that strongly asymmetric limit cycles can be observed in the system of three identical ring oscillators (3-gene networks known as Repressilators) globally coupled by signal molecule diffusion added to the model in a way like…

Adaptation and Self-Organizing Systems · Physics 2022-11-18 N. Stankevich , E. Volkov

In this paper, we study pairs of oscillators that are indirectly coupled via active (excitable) cells. We introduce a scalar phase model for coupled oscillators and excitable cells. We first show that one excitable and one oscillatory cell…

Dynamical Systems · Mathematics 2019-06-05 Derek Orr , Bard Ermentrout

A system of a quantum harmonic oscillator bi-linearly coupled with a Glauber amplifier is analysed considering a time-dependent Hamiltonian model. The Hilbert space of this system may be exactly subdivided into invariant finite dimensional…

Quantum Physics · Physics 2020-01-29 R. Grimaudo , V. I. Man'ko , M. A. Man'ko , A. Messina

Different types of synchronization states are found when non-linear chemical oscillators are embedded into an active medium that interconnects the oscillators but also contributes to the system dynamics. Using different theoretical tools,…

Adaptation and Self-Organizing Systems · Physics 2021-03-09 David García-Selfa , Gourab Ghoshal , Christian Bick , Juan Pérez-Mercader , Alberto P. Muñuzuri

A general theory of electronic excitations in aggregates of molecules coupled to intramolecular vibrations and the harmonic environment is developed for simulation of the third-order nonlinear spectroscopy signals. The model is applied in…

Chemical Physics · Physics 2014-01-17 Vytautas Butkus , Leonas Valkunas , Darius Abramavicius

In randomized experiments, the actual treatments received by some experimental units may differ from their treatment assignments. This non-compliance issue often occurs in clinical trials, social experiments, and the applications of…

Methodology · Statistics 2022-04-19 Jiyang Ren

Motivated by the aim to find new medical strategies to suppress undesirable neural synchronization we study the control of oscillations in a system of inhibitory coupled noisy oscillators. Using dynamical properties of inhibition, we find…

Disordered Systems and Neural Networks · Physics 2009-05-27 C. J. Tessone , E. Ullner , A. A. Zaikin , J. Kurths , R. Toral
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