Related papers: Mathematical Models of Bipolar Disorder
We provide a rather simple proof of a homogenization result for the bidomain model of cardiac electrophysiology. Departing from a microscopic cellular model, we apply the theory of two-scale convergence to derive the bidomain model. To…
We consider a model where a population of diffusively coupled limit-cycle oscillators, described by the complex Ginzburg-Landau equation, interacts nonlocally via an inertial field. For sufficiently high intensity of nonlocal inertial…
In recent decades, several mathematical models describing the pacemaker activity of the rabbit sinoatrial node have been developed. We demonstrate that it is not possible to establish the existence, uniqueness, and stability of a limit…
We develop a framework for the general interpretation of the stochastic dynamical system near a limit cycle. Such quasi-periodic dynamics are commonly found in a variety of nonequilibrium systems, including the spontaneous oscillations of…
There has been considerable interest in the disordered Bose Hubbard model (BHM) in recent years, particularly in the context of thermalization and many-body localization. We develop a two-particle irreducible (2PI) strong-coupling approach…
Using as a prototype example the harmonic oscillator we show how losing self-adjointness of the hamiltonian $H$ changes drastically the related functional structure. In particular, we show that even a small deviation from strict…
We study multifractality in a broad class of disordered systems which includes, e.g., the diluted x-y model. Using renormalized field theory we analyze the scaling behavior of cumulant averaged dynamical variables (in case of the x-y model…
Mathematical models for physiological processes aid qualitative understanding of the impact of various parameters on the underlying process. We analyse two such models for human physiological processes: the Mackey-Glass and the Lasota…
Oscillators - dynamical systems with stable periodic orbits - arise in many systems of physical, technological, and biological interest. The standard phase reduction, a model reduction technique based on isochrons, can be unsuitable for…
In real life, psychological and physiological states rarely change along a single dimension. Through self-tracking and discussions with clinicians, I have come to recognise with increasing clarity that sleep patterns, autonomic arousal,…
Current management of bipolar disorder relies on self-reported questionnaires and interviews with clinicians. The development of objective measures of deteriorating mood may also allow for early interventions to take place to avoid…
Sleep is essential for the maintenance of the brain and the body, yet many features of sleep are poorly understood and mathematical models are an important tool for probing proposed biological mechanisms. The most well-known mathematical…
We examine examples of weakly nonlinear systems whose steady states undergo a bifurcation with increasing forcing, such that a forced subsystem abruptly ceases to absorb additional energy, instead diverting it into an initially quiescent,…
We explore simple models aimed at the study of social contagion, in which contagion proceeds through two stages. When coupled with demographic turnover, we show that two-stage contagion leads to nonlinear phenomena which are not present in…
In this paper we review recent work on novel computing paradigms using coupled oscillatory dynamical systems. We explore systems of relaxation oscillators based on linear state transitioning devices, which switch between two discrete states…
Evidence from experimental studies shows that oscillations due to electro-mechanical coupling can be generated spontaneously in smooth muscle cells. Such cellular dynamics are known as \textit{pacemaker dynamics}. In this article we address…
We study two body dipolar scattering in two dimensions with a tilted polarization axis. This tilt reintroduces the anisotropic interaction in a controllable manner. As a function of this polarization angle we present the scattering results…
This study investigates a detailed analytical and numerical investigation of a nonlinear two-degree-of-freedom (2DOF) mechanical oscillator subjected to parametric excitation, magnetic stiffness nonlinearities, and dry friction. The…
Studying psychiatric illness has often been limited by difficulties in connecting symptoms and behavior to neurobiology. Computational psychiatry approaches promise to bridge this gap by providing formal accounts of the latent information…
We study the bifurcation of limit cycles from the periodic orbits of $2n$--dimensional linear centers $\dot{x} = A_0 x$ when they are perturbed inside classes of continuous and discontinuous piecewise linear differential systems of control…