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In this thesis, we prove several results concerning field-theoretic invariants of knots and 3-manifolds. In Chapter 2, for any knot $K$ in a closed, oriented 3-manifold $M$, we use $SU(2)$ representation spaces and the Lagrangian field…

We study the homology concordance group of knots in integer homology three-spheres which bound integer homology four-balls. Using knot Floer homology, we construct an infinite number of $\mathbb{Z}$-valued, linearly independent homology…

We propose and analyze a structure with which to organize the difference between a knot in the 3-sphere bounding a topologically embedded 2-disk in the 4-ball and it bounding a smoothly embedded disk. The n-solvable filtration of the…

The clasp number $c(K)$ of a knot $K$ is the minimum number of clasp singularities among all clasp disks bounded by $K$. It is known that the genus $g(K)$ and the unknotting number $u(K)$ are lower bounds of the clasp number, that is,…

We construct an infinite family of topologically slice knots that are not smoothly concordant to their reverses. More precisely, if T denotes the concordance group of topologically slice knots and R is the involution of T induced by string…

We study the group of rational concordance classes of codimension two knots in rational homology spheres. We give a full calculation of its algebraic theory by developing a complete set of new invariants. For computation, we relate these…

Any knot group is the image of the group of a prime knot by a homomorphism that preserves peripheral structure. In fact, there are infinitely many such prime knots. A related partial order on knots is defined, and its properties are…

We define a group-valued invariant of virtual knots and relate it to various other group-valued invariants of virtual knots, including the extended group of Silver-Williams and the quandle group of Manturov and Bardakov-Bellingeri. A…

The transient number of a knot K, denoted tr(K), is the minimal number of simple arcs that have to be attached to K, in order that K can be homotoped to a trivial knot in a regular neighborhood of the union of K and the arcs. We give a…

We develop purely algebraic methods for proving that a knot is prime. Our approach uses the Heegaard Floer polynomial in conjunction with classical knot-theoretic methods: cyclic, dihedral, and metacyclic covering spaces. The theory of…

We introduce and study the notion of equivariant $\mathbb{Q}$-sliceness for strongly invertible knots. On the constructive side, we prove that every Klein amphichiral knot, which is a strongly invertible knot admitting a compatible negative…

The cosmetic crossing conjecture posits that switching a non-trivial crossing in a knot diagram always changes the knot type. Generalizing work of Balm, Friedl, Kalfagianni and Powell, and of Lidman and Moore, we give an Alexander…

A geometric characterization of the Arf invariant of a knot in the 3-sphere is given in terms of two kinds of 4-dimensional bordisms, half-gropes and Whitney towers. These types of bordisms have associated complexities class and order which…

We consider the classical pretzel knots $P(a_1, a_2, a_3)$, where $a_1, a_2, a_3$ are positive odd integers. By using continuous paths of elliptic $\mathrm{SL}_2(\mathbb R)$-representations, we show that (i) the 3-manifold obtained by…

We use the famous knot-theoretic consequence of Freedman's disc theorem---knots with trivial Alexander polynomial bound a locally-flat disc in the 4-ball---to prove the following generalization. The degree of the Alexander polynomial of a…

We prove that if an alternating 3-braid knot has unknotting number one, then there must exist an unknotting crossing in any alternating diagram of it, and we enumerate such knots. The argument combines the obstruction to unknotting number…

We define an algebraic group comprising symmetric chain complexes which captures the first two stages of the Cochran-Orr-Teichner solvable filtration of the knot concordance group in a single invariant. To achieve this we impose additional…

We show that the 3-fold cyclic branched cover of any genus 2 two-bridge knot $K_{[-2q,2s,-2t,2l]}$ is an L-space and its fundamental group is not left-orderable. Therefore the family of 3-fold cyclic branched cover of any genus 2 two-bridge…

We prove that there exist infinitely many topologically slice knots which cannot bound a smooth null-homologous disk in any definite 4-manifold. Furthermore, we show that we can take such knots so that they are linearly independent in the…

We say that a knot $k_1$ in the $3$-sphere {\it $1$-dominates} another $k_2$ if there is a proper degree 1 map $E(k_1) \to E(k_2)$ between their exteriors, and write $k_1 \ge k_2$. When $k_1 \ge k_2$ but $k_1 \ne k_2$ we write $k_1 > k_2$.…