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Multilevel techniques are efficient approaches for solving the large linear systems that arise from discretized partial differential equations and other problems. While geometric multigrid requires detailed knowledge about the underlying…

Numerical Analysis · Mathematics 2023-01-23 Tareq. U. Zaman , Scott P. MacLachlan , Luke N. Olson , Matt West

In soft matter systems the local displacement field can be accessed directly by video microscopy enabling one to compute local strain fields and hence the elastic moduli using a coarse-graining procedure. We study this process for a simple…

Soft Condensed Matter · Physics 2015-05-14 K. Franzrahe , P. Nielaba , S. Sengupta

Markov state models (MSMs)---or discrete-time master equation models---are a powerful way of modeling the structure and function of molecular systems like proteins. Unfortunately, MSMs with sufficiently many states to make a quantitative…

Biomolecules · Quantitative Biology 2015-06-03 Gregory R. Bowman

In molecular dynamics and sampling of high dimensional Gibbs measures coarse-graining is an important technique to reduce the dimensionality of the problem. We will study and quantify the coarse-graining error between the coarse-grained…

Analysis of PDEs · Mathematics 2020-06-04 M. H. Duong , A. Lamacz , M. A. Peletier , A. Schlichting , U. Sharma

Numerical simulations of critical lattice systems are fundamentally limited by critical slowing down, as long-range correlations are typically established through slow temporal equilibration. A physically constrained generative framework…

Statistical Mechanics · Physics 2026-03-24 Sun Haoyuan

We present an effective evolution equation for a coarse-grained distribution function of a long-range-interacting system preserving the symplectic structure of the non-collisional Boltzmann, or Vlasov, equation. We first derive a general…

Statistical Mechanics · Physics 2020-07-01 Guido Giachetti , Alessandro Santini , Lapo Casetti

Sample-based Bayesian inference provides a route to uncertainty quantification in the geosciences, and inverse problems in general, though is very computationally demanding in the naive form that requires simulating an accurate computer…

Computation · Statistics 2019-04-12 Tiangang Cui , Colin Fox , Michael J O'Sullivan

A general scheme, which includes constructions of coarse-grained (CG) models, weighted ensemble dynamics (WED) simulations and cluster analyses (CA) of stable states, is presented to detect dynamical and thermodynamical properties in…

Soft Condensed Matter · Physics 2008-12-04 Xin Zhou

We present a new framework for coarse-graining molecular dynamics models for crystalline solids. The reduction method is based on a Galerkin projection to a subspace, whose dimension is much smaller than that of the full atomistic model.…

Numerical Analysis · Mathematics 2012-10-17 Xiantao Li

The accuracy of a large eddy simulation (LES) is determined by the accuracy of the model used to describe the effect of unresolved scales, the numerical errors of the resolved scales, and the optimality of the length scale that separates…

Computational Physics · Physics 2019-12-11 Siavash Toosi , Johan Larsson

Dynamical systems with large state-spaces are often expensive to thoroughly explore experimentally. Coarse-graining methods aim to define simpler systems which are more amenable to analysis and exploration; most current methods, however,…

Systems and Control · Computer Science 2016-11-01 Michalis Michaelides , Dimitrios Milios , Jane Hillston , Guido Sanguinetti

We propose a systematic coarse-grained representation of block copolymers, whereby each block is reduced to a single ``soft blob'' and effective intra- as well as intermolecular interactions act between centres of mass of the blocks. The…

Soft Condensed Matter · Physics 2009-11-11 C. I. Addison , J. P. Hansen , V. Krakoviack , A. A. Louis

Coarse-graining (CG) of molecular simulations simplifies the particle representation by grouping selected atoms into pseudo-beads and drastically accelerates simulation. However, such CG procedure induces information losses, which makes…

Machine Learning · Computer Science 2022-06-20 Wujie Wang , Minkai Xu , Chen Cai , Benjamin Kurt Miller , Tess Smidt , Yusu Wang , Jian Tang , Rafael Gómez-Bombarelli

Bottom-up coarse-grained (CG) modeling expands the spatial and temporal scales of molecular simulation by seeking a reduced, thermodynamically consistent representation of an atomistic model. Developments in CG theory have largely focused…

Chemical Physics · Physics 2025-03-28 Patrick G. Sahrmann , Gregory A. Voth

Multilevel methods represent a powerful approach in numerical solution of partial differential equations. The multilevel structure can also be used to construct estimates for total and algebraic errors of computed approximations. This paper…

Numerical Analysis · Mathematics 2024-05-13 Petr Vacek , Jan Papež , Zdeněk Strakoš

In random systems consisting of grains with size distributions the transport properties are difficult to explore by network models. However, the concentration dependence of effective conductivity and its critical properties can be…

Statistical Mechanics · Physics 2007-05-23 Ryszard Piasecki

A coarse-graining strategy, previously developed for polymer solutions, is extended here to mixtures of linear polymers and hard-sphere colloids. In this approach groups of monomers are mapped onto a single pseudoatom (a blob) and the…

Soft Condensed Matter · Physics 2015-01-07 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

Likelihood-based inference in stochastic non-linear dynamical systems, such as those found in chemical reaction networks and biological clock systems, is inherently complex and has largely been limited to small and unrealistically simple…

Computation · Statistics 2024-07-08 Ben Swallow , David A. Rand , Giorgos Minas

With the guidance offered by nonequilibrium statistical thermodynamics, simulation techniques are elevated from brute-force computer experiments to systematic tools for extracting complete, redundancy-free and consistent coarse grained…

Statistical Mechanics · Physics 2018-03-09 Hans Christian Öttinger

We formulate an effective-description framework for the dynamics of open quantum systems by extending the time-coarse-graining formalism to open systems. Our coarse-graining procedure efficiently removes high-frequency processes which are…

Quantum Physics · Physics 2018-01-17 Chang-Woo Lee , Changsuk Noh , Jaewan Kim
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