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In the classic view introduced by R. A. Fisher, a quantitative trait is encoded by many loci with small, additive effects. Recent advances in QTL mapping have begun to elucidate the genetic architectures underlying vast numbers of…

Populations and Evolution · Quantitative Biology 2013-10-04 Etienne Rajon , Joshua B. Plotkin

We consider the hypothesis that Evolution promotes population-wide genome patterns that, under randomization, ensures the External Validity of adaptations across population members. An adaptation is Externally Valid (EV) if its effect holds…

Populations and Evolution · Quantitative Biology 2021-08-17 Andre F. Ribeiro

We present a completely new version of our arithmetic model of the standard genetic code and compute in a straightforward manner the exact numeric degeneracies of the five multiplets without any trick for the doublets and the sextets, as we…

Other Quantitative Biology · Quantitative Biology 2009-08-10 Tidjani Negadi

The traditional approach of hand-crafting priors (such as sparsity) for solving inverse problems is slowly being replaced by the use of richer learned priors (such as those modeled by deep generative networks). In this work, we study the…

Machine Learning · Computer Science 2021-05-14 Viraj Shah , Rakib Hyder , M. Salman Asif , Chinmay Hegde

Accurately fitting the term structure of interest rates is critical to central banks and other market participants. The Nelson-Siegel and Nelson-Siegel-Svensson models are probably the best-known models for this purpose due to their…

Risk Management · Quantitative Finance 2021-08-05 Asif Lakhany , Andrej Pintar , Amber Zhang

In the biclustering problem, we seek to simultaneously group observations and features. While biclustering has applications in a wide array of domains, ranging from text mining to collaborative filtering, the problem of identifying…

Methodology · Statistics 2018-06-07 Eric C. Chi , Genevera I. Allen , Richard G. Baraniuk

We consider nonadaptive group testing with Bernoulli tests, where each item is placed in each test independently with some fixed probability. We give a tight threshold on the maximum number of tests required to find the defective set under…

Information Theory · Computer Science 2017-11-16 Matthew Aldridge

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution. Quantum computation is a new computational paradigm which exploits quantum resources to speed up information processing tasks. Therefore, it is…

Quantum Physics · Physics 2023-02-20 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

We consider the fundamental problems of approximately counting the numbers of edges and triangles in a graph in sublinear time. Previous algorithms for these tasks are significantly more efficient under a promise that the arboricity of the…

Data Structures and Algorithms · Computer Science 2025-09-25 Talya Eden , Ronitt Rubinfeld , Arsen Vasilyan

We represent the generalized Collatz function with the recursive ruler function r(2n) = r(n) + 1 and r(2n + 1) = 1. We generate even-only and odd-only Collatz subsequences that contain significantly fewer elements term by term, to 2 and 1,…

General Mathematics · Mathematics 2021-12-15 Robert Hill Nichols

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

Data Structures and Algorithms · Computer Science 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

In recent years, there has been increasing interest in explanation methods for neural model predictions that offer precise formal guarantees. These include abductive (respectively, contrastive) methods, which aim to compute minimal subsets…

Machine Learning · Computer Science 2023-05-03 Ouns El Harzli , Bernardo Cuenca Grau , Ian Horrocks

What is the productivity of Science? Can we measure an evolution of the production of mathematicians over history? Can we predict the waiting time till the proof of a challenging conjecture such as the P-versus-NP problem? Motivated by…

Physics and Society · Physics 2014-08-26 Ryohei Hisano , Didier Sornette

This Article introduces the generative reasonable person, a new tool for estimating how ordinary people judge reasonableness. As claims about AI capabilities often outpace evidence, the Article proceeds empirically: adapting randomized…

Computers and Society · Computer Science 2026-02-18 Yonathan A. Arbel

The existence of complex (multiple-step) genetic adaptations that are "irreducible" (i.e., all partial combinations are less fit than the original genotype) is one of the longest standing problems in evolutionary biology. In standard…

Populations and Evolution · Quantitative Biology 2014-10-17 Meredith V. Trotter , Daniel B. Weissman , Grant I. Peterson , Kayla M. Peck , Joanna Masel

In this paper we attack the Erdos-Straus conjecture by means of the structure of its solutions, extending and improving the results of a previous paper. Using previous results and supported by the works of Elsholtz and Tao and Monks and…

Number Theory · Mathematics 2024-04-17 Miguel Angel Lopez

We derive and analyze a generic, recursive algorithm for estimating all splits in a finite cluster tree as well as the corresponding clusters. We further investigate statistical properties of this generic clustering algorithm when it…

Machine Learning · Statistics 2021-11-02 Ingo Steinwart , Bharath K. Sriperumbudur , Philipp Thomann

Statistical analysis of DNA mixtures is known to pose computational challenges due to the enormous state space of possible DNA profiles. We propose a Bayesian network representation for genotypes, allowing computations to be performed…

Methodology · Statistics 2014-02-21 Therese Graversen , Steffen Lauritzen

Evolution is the theory that plants and animals today have come from kinds that have existed in the past. Scientists such as Charles Darwin and Alfred Wallace dedicate their life to observe how species interact with their environment, grow,…

Neural and Evolutionary Computing · Computer Science 2022-09-16 Manasa Josyula

Average-case analysis computes the complexity of an algorithm averaged over all possible inputs. Compared to worst-case analysis, it is more representative of the typical behavior of an algorithm, but remains largely unexplored in…

Optimization and Control · Mathematics 2021-10-05 Courtney Paquette , Bart van Merriënboer , Elliot Paquette , Fabian Pedregosa
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