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Motivated by recent studies of two-phase lipid vesicles possessing 2D solid domains integrated within a fluid bilayer phase, we study the shape equilibria of closed vesicles possessing a single planar, circular inclusion. While 2D solid…

Soft Condensed Matter · Physics 2024-04-16 Geunwoong Jeon , Justin Fagnoni , Hao Wan , Maria M. Santore , Gregory M. Grason

The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure…

Fluid Dynamics · Physics 2020-05-05 Paul G. Chen , J. M. Lyu , M. Jaeger , M. Leonetti

Coarse-grained continuous descriptions for lipid bilayers are typically based on minimizing the Helfrich energy. Such models consider the fluid properties of these structures only implicitly and have been shown to nicely reproduce…

Soft Condensed Matter · Physics 2026-04-29 Ingo Nitschke , Jan Magnus Sischka , Axel Voigt

In this survey article, we present two applications of surface curvatures in theoretical physics. The first application arises from biophysics in the study of the shape of cell vesicles involving the minimization of a mean curvature type…

Mathematical Physics · Physics 2024-06-14 Yisong Yang

We consider the impact of surface hydrodynamics on the interplay between curvature and composition in coarsening processes on model systems for biomembranes. This includes scaling laws and equilibrium configurations, which are investigated…

Soft Condensed Matter · Physics 2023-04-19 Elena Bachini , Veit Krause , Axel Voigt

Motivated by recent experimental work on multicomponent lipid membranes supported by colloidal scaffolds, we report an exhaustive theoretical investigation of the equilibrium configurations of binary mixtures on curved substrates. Starting…

Soft Condensed Matter · Physics 2018-09-12 Piermarco Fonda , Melissa Rinaldin , Daniela J. Kraft , Luca Giomi

We theoretically study the elastic deformation of a fluid membrane induced by an adhering spherical colloidal particle within the framework of a Helfrich energy. Based on a full optimization of the membrane shape we find a continuous…

Soft Condensed Matter · Physics 2009-11-07 Markus Deserno , Thomas Bickel

Correctly formulated continuum models for lipid-bilayer membranes present a significant challenge to computational mechanics. In particular, the mid-surface behavior is that of a 2-dimensional fluid, while the membrane resists bending much…

Soft Condensed Matter · Physics 2017-03-08 Siming Zhao , Timothy Healey , Qingdu Li

The paper studies the equilibrium configurations of inextensible elastic membranes exhibiting lateral fluidity. Using a continuum description of the membrane's motions based on the surface Navier--Stokes equations with bending forces, the…

Fluid Dynamics · Physics 2023-06-21 Maxim A. Olshanskii

Liquid crystals with molecules constrained to the tangent bundle of a curved surface show interesting phenomena resulting from the tight coupling of the elastic and bulk free energies of the liquid crystal with geometric properties of the…

Soft Condensed Matter · Physics 2021-03-17 Ingo Nitschke , Sebastian Reuther , Axel Voigt

Consider a closed lipid membrane (vesicle), modeled as a two-dimensional surface, described by a geometrical hamiltonian that depends on its extrinsic curvature. The vanishing of its first variation determines the equilibrium configurations…

Soft Condensed Matter · Physics 2007-05-23 Riccardo Capovilla , Jemal Guven , Jose' Antonio Santiago

Motivated by recent experiments on bilayer polyhedra composed of amphiphilic molecules, we study the elastic bending energies of bilayer vesicles forming polyhedral shapes. Allowing for segregation of excess amphiphiles along the ridges of…

Soft Condensed Matter · Physics 2011-06-13 Christoph A. Haselwandter , Rob Phillips

By means of Surface Evolver (Exp. Math,1,141 1992), a software package of brute-force energy minimization over a triangulated surface developed by the geometry center of University of Minnesota, we have numerically searched the…

Biological Physics · Physics 2009-10-31 Yan Jie , Liu Quan-Hui , Liu Ji-Xing , Ou-Yang Zhong-Can

The purpose of this paper is to study the shapes and stabilities of bio-membranes within the framework of exterior differential forms. After a brief review of the current status in theoretical and experimental studies on the shapes of…

Soft Condensed Matter · Physics 2007-05-23 Z. C. Tu , Z. C. Ou-Yang

We investigate the equilibrium configurations of closed planar elastic curves of fixed length, whose stiffness, also known as the bending rigidity, depends on an additional density variable. The underlying variational model relies on the…

Analysis of PDEs · Mathematics 2021-10-14 Katharina Brazda , Gaspard Jankowiak , Christian Schmeiser , Ulisse Stefanelli

Vesicles are important surrogate structures made up of multiple phospholipids and cholesterol distributed in the form of a lipid bilayer. Tubular vesicles can undergo pearling i.e., formation of beads on the liquid thread akin to the…

Soft Condensed Matter · Physics 2024-03-01 Anirudh Venkatesh , Aman Bhargava , Vivek Narsimhan

This review reports some key results in theoretical investigations on configurations of lipid membranes and presents several challenges in this field which involve (i) exact solutions to the shape equation of lipid vesicles; (ii) exact…

Soft Condensed Matter · Physics 2017-07-27 Z. C. Tu

Lipid bilayer membranes are commonly modeled as area-preserving fluid surfaces that resist bending. There appear to be two schools of thought in the literature concerning the actual area constraint. In some works the total or global area…

Biological Physics · Physics 2015-06-23 Sanjay Dharmavaram , Timothy J. Healey

The morphology of spherically confined flexoelectric fluid membrane vesicles in an external uniform electric field is studied numerically. Due to the deformations induced by the confinement, the membrane becomes polarized resulting in an…

Biological Physics · Physics 2020-11-03 Niloufar Abtahi , Lila Bouzar , Nadia Saidi-Amroun , Martin Michael Müller

Within the framework of the Helfrich elastic theory of membranes and of differential geometry we study the possible instabilities of spherical vesicles towards double bubbles. We find that not only temperature, but also magnetic fields can…

Soft Condensed Matter · Physics 2009-08-03 O. V. Manyuhina , A. Fasolino , P. C. M. Christianen , M. I. Katsnelson