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High\-cardinality categorical variables pose significant challenges in machine learning, particularly in terms of computational efficiency and model interpretability. Traditional one\-hot encoding often results in high\-dimensional sparse…

Machine Learning · Computer Science 2025-01-13 Zixuan Liang

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

This paper considers the problem of distributed source coding for a large network. A major obstacle that poses an existential threat to practical deployment of conventional approaches to distributed coding is the exponential growth of the…

Information Theory · Computer Science 2013-01-08 Kumar Viswanatha , Sharadh Ramaswamy , Ankur Saxena , Emrah Akyol , Kenneth Rose

Motivation: New long read sequencers promise to transform sequencing and genome assembly by producing reads tens of kilobases long. However their high error rate significantly complicates assembly and requires expensive correction steps to…

Genomics · Quantitative Biology 2017-07-18 Antoine Recanati , Thomas Brüls , Alexandre d'Aspremont

Data-driven algorithm selection is a powerful approach for choosing effective heuristics for computational problems. It operates by evaluating a set of candidate algorithms on a collection of representative training instances and selecting…

Machine Learning · Computer Science 2025-12-04 Vaggos Chatziafratis , Ishani Karmarkar , Yingxi Li , Ellen Vitercik

Analysis of large-scale sequential data has been one of the most crucial tasks in areas such as bioinformatics, text, and audio mining. Existing string kernels, however, either (i) rely on local features of short substructures in the…

Machine Learning · Computer Science 2019-12-02 Lingfei Wu , Ian En-Hsu Yen , Siyu Huo , Liang Zhao , Kun Xu , Liang Ma , Shouling Ji , Charu Aggarwal

It is known that the majority of the human genome consists of repeated sequences. Furthermore, it is believed that a significant part of the rest of the genome also originated from repeated sequences and has mutated to its current form. In…

Information Theory · Computer Science 2014-01-21 Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. T cell receptors (TCRs) are essential proteins for the adaptive immune system, and their specific recognition of antigens plays a crucial role in the…

Machine Learning · Computer Science 2023-09-07 Zahra Tayebi , Sarwan Ali , Prakash Chourasia , Taslim Murad , Murray Patterson

In an effort to catalog insect biodiversity, we propose a new large dataset of hand-labelled insect images, the BIOSCAN-Insect Dataset. Each record is taxonomically classified by an expert, and also has associated genetic information…

Advances in methods of biological data collection are driving the rapid growth of comprehensive datasets across clinical and research settings. These datasets provide the opportunity to monitor biological systems in greater depth and at…

Molecular Networks · Quantitative Biology 2025-01-20 Joshua Pickard , Cooper Stansbury , Amit Surana , Lindsey Muir , Anthony Bloch , Indika Rajapakse

High-dimensional malware datasets often exhibit feature redundancy, instability, and scalability limitations, which hinder the effectiveness and interpretability of machine learning-based malware detection systems. Although feature…

Cryptography and Security · Computer Science 2026-01-23 Ajvad Haneef K , Karan Kuwar Singh , Madhu Kumar S D

Without prior knowledge, distinguishing different languages may be a hard task, especially when their borders are permeable. We develop an extension of spectral clustering -- a powerful unsupervised classification toolbox -- that is shown…

Computation and Language · Computer Science 2008-10-08 Richard Nock , Pascal Vaillant , Frank Nielsen , Claudia Henry

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

High dimensional and heterogeneous count data are collected in various applied fields. In this paper, we look closely at high-resolution sequencing data on the microbiome, which have enabled researchers to study the genomes of entire…

Methodology · Statistics 2024-01-12 Veronica Vinciotti , Pariya Behrouzi , Reza Mohammadi

Synchronization strings are recently introduced by Haeupler and Shahrasbi [HS17a] in the study of codes for correcting insertion and deletion errors (insdel codes). A synchronization string is an encoding of the indices of the symbols in a…

Information Theory · Computer Science 2017-10-31 Kuan Cheng , Xin Li , Ke Wu

The bacterial microbiome is increasingly being recognised as a key factor in human health, driven in large part by datasets collected using 16S rRNA (ribosomal ribonucleic acid) gene sequencing, which enable cost-effective quantification of…

Applications · Statistics 2025-09-08 Jonathan Ish-Horowicz , Sarah Filippi

We introduce a new family of binary linear codes suitable for steganographic matrix embedding. The main characteristic of the codes is the staircase random block structure of the generator matrix. We propose an efficient list decoding…

Multimedia · Computer Science 2015-08-11 Simona Samardjiska , Danilo Gligoroski

Classification of high-dimensional spectroscopic data is a common task in analytical chemistry. Well-established procedures like support vector machines (SVMs) and partial least squares discriminant analysis (PLS-DA) are the most common…

Applications · Statistics 2021-01-29 Andrea Cappozzo , Ludovic Duponchel , Francesca Greselin , Thomas Brendan Murphy

Applications in machine learning, optimization, and control require the sequential selection of a few system elements, such as sensors, data, or actuators, to optimize the system performance across multiple time steps. However, in…

Machine Learning · Statistics 2020-12-17 Vasileios Tzoumas , Ali Jadbabaie , George J. Pappas

High throughput technologies have become the practice of choice for comparative studies in biomedical applications. Limited number of sample points due to sequencing cost or access to organisms of interest necessitates the development of…

Methodology · Statistics 2018-07-17 Ariana Broumand , Siamak Zamani Dadaneh