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This paper proposes a binarization scheme for vectors of high dimension based on the recent concept of anti-sparse coding, and shows its excellent performance for approximate nearest neighbor search. Unlike other binarization schemes, this…

Computer Vision and Pattern Recognition · Computer Science 2011-10-27 Hervé Jégou , Teddy Furon , Jean-Jacques Fuchs

High-throughput screening, in which multiwell plates are used to test large numbers of compounds against specific targets, is widely used across many areas of the biological sciences and most prominently in drug discovery. We propose a…

Deep Neural Networks (DNNs) have been shown to be susceptible to memorization or overfitting in the presence of noisily-labelled data. For the problem of robust learning under such noisy data, several algorithms have been proposed. A…

Machine Learning · Computer Science 2022-12-06 Deep Patel , P. S. Sastry

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

Active, responsive, nonequilibrium materials, at the forefront of materials engineering, offer dynamical restructuring, mobility and other complex life-like properties. Yet, this enhanced functionality comes with significant amplification…

Embedding image features into a binary Hamming space can improve both the speed and accuracy of large-scale query-by-example image retrieval systems. Supervised hashing aims to map the original features to compact binary codes in a manner…

Machine Learning · Computer Science 2016-11-17 Guosheng Lin , Chunhua Shen , Anton van den Hengel

We investigate the concept of deep barcodes and propose two methods to generate them in order to expedite the process of classification and retrieval of histopathology images. Since binary search is computationally less expensive, in terms…

Image and Video Processing · Electrical Eng. & Systems 2018-05-24 Meghana Dinesh Kumar , Morteza Babaie , Hamid Tizhoosh

Causal structure learning refers to a process of identifying causal structures from observational data, and it can have multiple applications in biomedicine and health care. This paper provides a practical review and tutorial on scalable…

Machine Learning · Computer Science 2023-01-20 Pulakesh Upadhyaya , Kai Zhang , Can Li , Xiaoqian Jiang , Yejin Kim

The effectiveness of watermark algorithms in AI-generated text identification has garnered significant attention. Concurrently, an increasing number of watermark algorithms have been proposed to enhance the robustness against various…

Cryptography and Security · Computer Science 2024-10-01 Xianheng Feng , Jian Liu , Kui Ren , Chun Chen

Multiple string matching is known as locating all the occurrences of a given number of patterns in an arbitrary string. It is used in bio-computing applications where the algorithms are commonly used for retrieval of information such as…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-07 S. Arudchutha , T. Nishanthy , R. G. Ragel

State-of-the-art branch and bound algorithms for mixed integer programming make use of special methods for making branching decisions. Strategies that have gained prominence include modern variants of so-called strong branching (Applegate,…

Data Structures and Algorithms · Computer Science 2016-01-08 Fred Glover , Vladimir Shylo , Oleg Shylo

Synthetic Biology is the new engineering-based approach to biology that includes applications of designing complex biological devices. At present, it is not yet clear what will emerge as the defining principles of Synthetic Biology. One…

Quantitative Methods · Quantitative Biology 2011-03-30 A. X. C. N. Valente , Stephen S. Fong

We present a framework based on conditional entropy and the Dirichlet distribution for classifying chromosomes based on the degree to which they use synonymous codons uniformly or preferentially, that is, whether or not codons that code for…

Genomics · Quantitative Biology 2015-10-15 Andrew Hart , Servet Martínez

Evolution in its course found a variety of solutions to the same optimisation problem. The advent of high-throughput genomic sequencing has made available extensive data from which, in principle, one can infer the underlying structure on…

Quantitative Methods · Quantitative Biology 2016-04-12 Silvia Grigolon , Silvio Franz , Matteo Marsili

String data are often disseminated to support applications such as location-based service provision or DNA sequence analysis. This dissemination, however, may expose sensitive patterns that model confidential knowledge. In this paper, we…

A weakly constrained code is a collection of finite-length strings over a finite alphabet in which certain substrings or patterns occur according to some prescribed frequencies. Buzaglo and Siegel (ITW 2017) gave a construction of weakly…

Information Theory · Computer Science 2024-08-15 Prachi Mishra , Navin Kashyap

Gram-negative bacteria are a serious health concern due to the strong multidrug resistance that they display, partly due to the presence of a permeability barrier comprising two membranes with active efflux. New approaches are urgently…

Genome assembly using high throughput data with short reads, arguably, remains an unresolvable task in repetitive genomes, since when the length of a repeat exceeds the read length, it becomes difficult to unambiguously connect the flanking…

Quantitative Methods · Quantitative Biology 2013-07-31 Viraj Deshpande , Eric DK Fung , Son Pham , Vineet Bafna

Supervised and semi-supervised semantic segmentation algorithms require significant amount of annotated data to achieve a good performance. In many situations, the data is either not available or the annotation is expensive. The objective…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Ram Krishna Pandey , Akshit Achara

We propose a solution on the stopping criterion in segmenting inhomogeneous DNA sequences with complex statistical patterns. This new stopping criterion is based on Bayesian Information Criterion (BIC) in the model selection framework. When…

Biological Physics · Physics 2009-11-07 Wentian Li