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Information on the structure of molecules, retrieved via biochemical databases, plays a pivotal role in various disciplines, such as metabolomics, systems biology, and drug discovery. However, no such database can be complete, and the…

Biomolecules · Quantitative Biology 2023-08-25 Casper Asbjørn Eriksen , Jakob Lykke Andersen , Rolf Fagerberg , Daniel Merkle

As information becomes increasingly sizable for organizations to maintain the challenge of organizing data still remains. More importantly, the on-going process of analysing incoming data occurs on a continual basis and organizations should…

Databases · Computer Science 2021-05-19 Bryar A. Hassan , Shko M. Qader

This paper presents an evolutionary algorithm with a new goal-sequence domination scheme for better decision support in multi-objective optimization. The approach allows the inclusion of advanced hard/soft priority and constraint…

Artificial Intelligence · Computer Science 2011-06-02 E. F. Khor , T. H. Lee , R. Sathikannan , K. C. Tan

Human-data interaction (HDI) presents fundamentally different challenges from traditional data management. HDI systems must meet latency, correctness, and consistency needs that stem from usability rather than query semantics; failing to…

Databases · Computer Science 2026-01-14 Eugene Wu , Yiru Chen , Haneen Mohammed , Zezhou Huang

Scanning and filtering over multi-dimensional tables are key operations in modern analytical database engines. To optimize the performance of these operations, databases often create clustered indexes over a single dimension or…

Databases · Computer Science 2020-06-25 Vikram Nathan , Jialin Ding , Mohammad Alizadeh , Tim Kraska

The ability to collect and analyze large amounts of data is a growing problem within the scientific community. The growing gap between data and users calls for innovative tools that address the challenges faced by big data volume, velocity…

Databases · Computer Science 2016-08-01 Vijay Gadepally , Jeremy Kepner

We view Digital Ecosystems to be the digital counterparts of biological ecosystems, which are considered to be robust, self-organising and scalable architectures that can automatically solve complex, dynamic problems. So, this work is…

Multiagent Systems · Computer Science 2009-10-06 Gerard Briscoe

Contemporary database systems, while effective, suffer severe issues related to complexity and usability, especially among individuals who lack technical expertise but are unfamiliar with query languages like Structured Query Language…

Databases · Computer Science 2025-07-25 M. Tedeschi , S. Rizwan , C. Shringi , V. Devram Chandgir , S. Belich

Most research on data discovery has so far focused on improving individual discovery operators such as join, correlation, or union discovery. However, in practice, a combination of these techniques and their corresponding indexes may be…

Databases · Computer Science 2024-12-02 Mahdi Esmailoghli , Christoph Schnell , Renée J. Miller , Ziawasch Abedjan

Characterizing the dynamic interactive patterns of complex systems helps gain in-depth understanding of how components interrelate with each other while performing certain functions as a whole. In this study, we present a novel multimodal…

Machine Learning · Computer Science 2019-01-07 Miaolin Fan , Chun-An Chou , Sheng-Che Yen , Yingzi Lin

Research in data warehousing and OLAP has produced important technologies for the design, management and use of information systems for decision support. With the development of Internet, the availability of various types of data has…

What determines biodiversity in nature is a prominent issue in ecology, especially in biotic resource systems that are typically devoid of cross-feeding. Here, we show that by incorporating pairwise encounters among consumer individuals…

Populations and Evolution · Quantitative Biology 2025-06-18 Ju Kang , Shijie Zhang , Yiyuan Niu , Xin Wang

Here we present ComPPI, a cellular compartment specific database of proteins and their interactions enabling an extensive, compartmentalized protein-protein interaction network analysis (http://ComPPI.LinkGroup.hu). ComPPI enables the user…

Molecular Networks · Quantitative Biology 2015-01-14 Daniel V. Veres , David M. Gyurko , Benedek Thaler , Kristof Z. Szalay , David Fazekas , Tamas Korcsmaros , Peter Csermely

Biologically-inspired AI agent frameworks claim reliability benefits through structural guarantees adapted from gene regulatory networks, immune systems, and metabolic control. These claims are rarely tested empirically against simpler…

Quantitative Methods · Quantitative Biology 2026-05-18 Bogdan Banu

The data warehousing is becoming increasingly important in terms of strategic decision making through their capacity to integrate heterogeneous data from multiple information sources in a common storage space, for querying and analysis. So…

Databases · Computer Science 2012-05-04 Phuc V. Nguyen

Black-box optimization (BBO) has a broad range of applications, including automatic machine learning, engineering, physics, and experimental design. However, it remains a challenge for users to apply BBO methods to their problems at hand…

Machine Learning · Computer Science 2021-11-05 Yang Li , Yu Shen , Wentao Zhang , Yuanwei Chen , Huaijun Jiang , Mingchao Liu , Jiawei Jiang , Jinyang Gao , Wentao Wu , Zhi Yang , Ce Zhang , Bin Cui

The wealth of data being gathered about humans and their surroundings drives new machine learning applications in various fields. Consequently, more and more often, classifiers are trained using not only numerical data but also complex data…

Machine Learning · Computer Science 2022-04-13 Maciej Piernik , Dariusz Brzezinski , Pawel Zawadzki

Presently, large enterprises rely on database systems to manage their data and information. These databases are useful for conducting daily business transactions. However, the tight competition in the marketplace has led to the concept of…

Databases · Computer Science 2012-12-11 Youssef Bassil

Many living and non-living complex systems can be modeled and understood as collective systems made of heterogeneous components that self-organize and generate nontrivial morphological structures and behaviors. This chapter presents a brief…

Adaptation and Self-Organizing Systems · Physics 2018-01-09 Hiroki Sayama

Genomic data are becoming increasingly valuable as we develop methods to utilize the information at scale and gain a greater understanding of how genetic information relates to biological function. Advances in synthetic biology and the…