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A feedback mechanism that involves the proteins p53 and mdm2, induces cell death as a controled response to severe DNA damage. A minimal model for this mechanism demonstrates that the respone may be dynamic and connected with the time…

Disordered Systems and Neural Networks · Physics 2009-11-07 G. Tiana , M. H. Jensen , K. Sneppen

Persistent neural activity underlying working memory requires sustained synaptic transmission, yet the metabolic and neurotransmitter support provided by astrocyte networks is largely absent from spatially extended neural circuit models. We…

Neurons and Cognition · Quantitative Biology 2026-04-14 Noah Palmer , Heather L. Cihak , Daniele Avitabile , Zachary P. Kilpatrick

In our research, we attempt to help people recognize their brain state of concentration or relaxation more conveniently and in real time. Considering the inconvenience of wearing traditional multiple electrode electroencephalographs, we…

Human-Computer Interaction · Computer Science 2015-09-28 Zhen Li , Jianjun Xu , Tingshao Zhu

In this work we study the detection of weak stimuli by spiking neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present…

Neurons and Cognition · Quantitative Biology 2009-06-04 Jorge F. Mejias , Joaquin J. Torres

Cortical neurons are subject to sustained and irregular synaptic activity which causes important fluctuations of the membrane potential (Vm). We review here different methods to characterize this activity and its impact on spike generation.…

Neurons and Cognition · Quantitative Biology 2009-04-29 Zuzanna Piwkowska , Martin Pospischil , Romain Brette , Julia Sliwa , Michelle Rudolph-Lilith , Thierry Bal , Alain Destexhe

An understanding how neurological disorders lead to mechanical dysfunction of the esophagus requires knowledge of the neural circuit of the enteric nervous system. Historically, this has been elusive. Here, we present an empirically guided…

Neurons and Cognition · Quantitative Biology 2024-03-04 Guy Elisha , Sourav Halder , Xinyi Liu , Dustin A. Carlson , Peter J. Kahrilas , John E. Pandolfino , Neelesh A. Patankar

Population-wide oscillations are ubiquitously observed in mesoscopic signals of cortical activity. In these network states a global oscillatory cycle modulates the propensity of neurons to fire. Synchronous activation of neurons has been…

Neurons and Cognition · Quantitative Biology 2017-07-04 Tobias Kühn , Moritz Helias

We consider a real-time communication system with noisy feedback consisting of a Markov source, a forward and a backward discrete memoryless channels, and a receiver with finite memory. The objective is to design an optimal communication…

Information Theory · Computer Science 2007-09-25 Aditya Mahajan , Demosthenis Teneketzis

Time--delayed feedback is exploited for controlling noise--induced motion in coherence resonance oscillators. Namely, under the proper choice of time delay, one can either increase or decrease the regularity of motion. It is shown that in…

Statistical Mechanics · Physics 2009-11-10 N. B. Janson , A. G. Balanov , E. Schoell

During sleep, the hippocampus recapitulates neuronal patterns corresponding to behavioral trajectories during previous experiences. This hippocampal replay supports the formation of long-term memories. Yet, whether replay originates within…

Neurons and Cognition · Quantitative Biology 2022-05-06 Adrien Peyrache

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain. To understand the underlying synaptic mechanisms, a fundamental approach is to study the dynamics of excitatory and inhibitory conductances of each…

Neurons and Cognition · Quantitative Biology 2017-10-17 Songting Li , Nan Liu , Xiaohui Zhang , Douglas Zhou , David Cai

We study both analytically and numerically the effect of presynaptic noise on the transmission of information in attractor neural networks. The noise occurs on a very short-time scale compared to that for the neuron dynamics and it produces…

Neurons and Cognition · Quantitative Biology 2007-05-23 J. M. Cortes , J. J. Torres , J. Marro , P. L. Garrido , H. J. Kappen

Precise spatio-temporal patterns of neuronal action potentials underly e.g. sensory representations and control of muscle activities. However, it is not known how the synaptic efficacies in the neuronal networks of the brain adapt such that…

Neurons and Cognition · Quantitative Biology 2015-02-24 Christian Albers , Maren Westkott , Klaus Pawelzik

Major Depressive Disorder (MDD) is a highly prevalent mental health condition, and a deeper understanding of its neurocognitive foundations is essential for identifying how core functions such as emotional and self-referential processing…

New results for attenuation and damping of electromagnetic fields in rigid conducting media are derived under the conjugate influence of inertia due to charge carriers and displacement current. Inertial effects are described by a relaxation…

Classical Physics · Physics 2009-03-03 F. E. M. Silveira , J. A. S. Lima

Short-term synaptic plasticity (STSP) affects the efficiency of synaptic transmission for persistent presynaptic activities. We consider attractor neural networks, for which the attractors are given, in the absence of STSP, by cell…

Neurons and Cognition · Quantitative Biology 2019-04-09 Bulcsú Sándor , Claudius Gros

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

Neurons and Cognition · Quantitative Biology 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

Recently, Xu et al. [Phys. Rev. A 86, 012113(2012)] explored the behavior of the entropic uncertainty relation under the influence of local unital and nonunital noisy channels for a class of Bell-diagonal states. We here reform their…

Quantum Physics · Physics 2017-10-18 Youneng Guo , Maofa Fang , Ke Zeng

Synaptic efficacy between neurons is known to change within a short time scale dynamically. Neurophysiological experiments show that high-frequency presynaptic inputs decrease synaptic efficacy between neurons. This phenomenon is called…

Disordered Systems and Neural Networks · Physics 2015-05-28 Yosuke Otsubo , Kenji Nagata , Masafumi Oizumi , Masato Okada

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout