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In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jean-Pascal Pfister , Taro Toyoizumi , David Barber , Wulfram Gerstner

Biological networks display a variety of activity patterns reflecting a web of interactions that is complex both in space and time. Yet inference methods have mainly focused on reconstructing, from the network's activity, the spatial…

Neurons and Cognition · Quantitative Biology 2015-08-19 Cristiano Capone , Carla Filosa , Guido Gigante , Federico Ricci-Tersenghi , Paolo del Giudice

We study the effects of network topology on the response of networks of coupled discrete excitable systems to an external stochastic stimulus. We extend recent results that characterize the response in terms of spectral properties of the…

Disordered Systems and Neural Networks · Physics 2015-03-18 Daniel B. Larremore , Woodrow L. Shew , Edward Ott , Juan G. Restrepo

Synchronization across long neural distances is a functionally important phenomenon. In order to access the mechanistic basis of long-range synchrony, we constructed an experimental model that enables monitoring of spiking activities over…

Neurons and Cognition · Quantitative Biology 2018-02-23 Hanna Keren , Shimon Marom

Recent evidence in rodent cerebral cortex and olfactory bulb suggests that short-term dynamics of excitatory synaptic transmission is correlated to stereotypical connectivity motifs. It was observed that neurons with short-term facilitating…

Neurons and Cognition · Quantitative Biology 2016-04-08 Eleni Vasilaki , Michele Giugliano

The information of spiking neural networks (SNNs) are propagated between the adjacent biological neuron by spikes, which provides a computing paradigm with the promise of simulating the human brain. Recent studies have found that the time…

Neural and Evolutionary Computing · Computer Science 2022-05-05 Pengfei Sun , Longwei Zhu , Dick Botteldooren

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these…

Neurons and Cognition · Quantitative Biology 2013-03-11 Sungwoo Ahn , Leonid L. Rubchinsky

This paper studies the performance of a feedback control loop closed via an error-free digital communication channel with transmission delay. The system comprises a discrete-time noisy linear time-invariant (LTI) plant whose single…

Systems and Control · Computer Science 2018-09-05 M. Barforooshan , M. S. Derpich , P. A. Stavrou , J. Østergaard

Neural activity exhibits a vast range of timescales that can be several fold larger than the membrane time constant of individual neurons. Two types of mechanisms have been proposed to explain this conundrum. One possibility is that large…

Neurons and Cognition · Quantitative Biology 2019-03-26 Manuel Beiran , Srdjan Ostojic

The collective dynamics of a network of excitable nodes changes dramatically when inhibitory nodes are introduced. We consider inhibitory nodes which may be activated just like excitatory nodes but, upon activating, decrease the probability…

Neurons and Cognition · Quantitative Biology 2014-04-03 Daniel B. Larremore , Woodrow L. Shew , Edward Ott , Francesco Sorrentino , Juan G. Restrepo

Stochastic control problems with delay are challenging due to the path-dependent feature of the system and thus its intrinsic high dimensions. In this paper, we propose and systematically study deep neural networks-based algorithms to solve…

Optimization and Control · Mathematics 2021-06-18 Jiequn Han , Ruimeng Hu

Diluted neural networks with continuous neurons and nonmonotonic transfer function are studied, with both fixed and dynamic synapses. A noisy stimulus with periodic variance results in a mechanism for controlling chaos in neural systems…

Disordered Systems and Neural Networks · Physics 2009-10-31 D. Caroppo , M. Mannarelli , G. Nardulli , S. Stramaglia

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

Neurotransmitter receptor molecules, concentrated in postsynaptic domains along with scaffold and a number of other molecules, are key regulators of signal transmission across synapses. Employing experiment and theory, we develop a…

Neurons and Cognition · Quantitative Biology 2015-05-20 Christoph A. Haselwandter , Martino Calamai , Mehran Kardar , Antoine Triller , Rava Azeredo da Silveira

In this paper, a new cooperation structure for spectrum sensing in cognitive radio networks is proposed which outperforms the existing commonly-used ones in terms of energy efficiency. The efficiency is achieved in the proposed design by…

Information Theory · Computer Science 2015-09-11 Younes Abdi , Tapani Ristaniemi

Neural variability plays a central role in neural coding and neuronal network dynamics. Unreliability of synaptic transmission is a major source of neural variability: synaptic neurotransmitter vesicles are released probabilistically in…

Neurons and Cognition · Quantitative Biology 2012-10-29 Steven Reich , Robert Rosenbaum

The impairment of cognitive function in Alzheimer's is clearly correlated to synapse loss. However, the mechanisms underlying this correlation are only poorly understood. Here, we investigate how the loss of excitatory synapses in sparsely…

Neurons and Cognition · Quantitative Biology 2021-01-27 Claudia Bachmann , Tom Tetzlaff , Renato Duarte , Abigail Morrison

Neurons are connected to other neurons by axons and dendrites that conduct signals with finite velocities, resulting in delays between the firing of a neuron and the arrival of the resultant impulse at other neurons. Since delays greatly…

Neurons and Cognition · Quantitative Biology 2021-08-25 Akke Mats Houben

Since the first recordings made of evoked action potentials it has become apparent that the responses of individual neurons to ongoing physiologically relevant input, are highly variable. This variability is manifested in non-stationary…

Neurons and Cognition · Quantitative Biology 2010-08-10 Avner Wallach , Danny Eytan , Asaf Gal , Christoph Zrenner , Ron Meir , Shimon Marom

Recurrent neural networks with balanced excitation and inhibition exhibit irregular asynchronous dynamics, which is fundamental for cortical computations. Classical balance mechanisms require strong external inputs to sustain finite firing…

Neurons and Cognition · Quantitative Biology 2025-10-21 David Angulo-Garcia , Alessandro Torcini
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