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Related papers: Topological interactions in DNA catenanes

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Epistasis describes the phenomenon that mutations at different loci do not have independent effects with regard to certain phenotypes. Understanding the global epistatic landscape is vital for many genetic and evolutionary theories. Current…

Molecular Networks · Quantitative Biology 2015-02-11 Brandon Barker , Lin Xu , Zhenglong Gu

Nucleosome core particle is a dynamic structure -- DNA may transiently peel off the histone octamer surface due to thermal fluctuations or the action of chromatin remodeling enzymes. Partial DNA unwrapping enables easier access of…

Genomics · Quantitative Biology 2018-10-17 Răzvan V. Chereji , Alexandre V. Morozov

The behaviour of elastic structures undergoing large deformations is the result of the competition between confining conditions, self-avoidance and elasticity. This combination of multiple phenomena creates a geometrical frustration that…

Soft Condensed Matter · Physics 2015-05-19 Mokhtar Adda-Bedia , Arezki Boudaoud , Laurent Boué , Stephanie Deboeuf

DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of the double helix. In fact the persistence length obtained by…

Soft Condensed Matter · Physics 2009-10-30 Philip Nelson

The interplay between non-trivial band topology and strong electronic correlations is a central challenge in modern condensed matter physics. We investigate this competition on a two-leg ladder model with a p-wave-like hybridisation between…

Strongly Correlated Electrons · Physics 2025-11-13 Aminul Hussain , Nisa Ara , Rudranil Basu , Sudeshna Sen

We construct a gene network based on expression data from DNA microarray experiments, by establishing a link between two genes whenever the Pearson's correlation coefficient between their expression profiles is higher than a certain cutoff.…

Statistical Mechanics · Physics 2007-05-23 P. Provero

We consider atoms interacting each other through the topological structure of a complex network and investigate lattice vibrations of the system, the quanta of which we call {\em netons} for convenience. The density of neton levels,…

Disordered Systems and Neural Networks · Physics 2007-05-23 Beom Jun Kim , H. Hong , M. Y. Choi

The elastic and inelastic profiles have been derived from the measured elastic differential cross section data with the help of exact impact parameter representation of elastic scattering amplitude. The results obtained for $pp$ scattering…

High Energy Physics - Phenomenology · Physics 2007-05-23 Vojtech Kundrat , Milos Lokajicek , D. Krupa

Previous efforts in complex networks research focused mainly on the topological features of such networks, but now also encompass the dynamics. In this Letter we discuss the relationship between structure and dynamics, with an emphasis on…

When the DNA double helix is subjected to external forces it can stretch elastically to elongations reaching 100% of its natural length. These distortions, imposed at the mesoscopic or macroscopic scales, have a dramatic effect on…

Materials Science · Physics 2009-11-13 Ryan Barnett , Paul Maragakis , Ari Turner , Maria Fyta , Efthimios Kaxiras

Many structures inside the cell such as nucleosomes and protein-mediated DNA loops contain sharply bent double-stranded (ds) DNA. Therefore, the energetics of strong dsDNA bending constitutes an essential part of cellular thermodynamics.…

Biological Physics · Physics 2014-11-05 Tung T. Le , Harold D. Kim

DNA is now firmly established as a versatile and robust platform for achieving synthetic nanostructures. While the folding of single molecules into complex structures is routinely achieved through engineering basepair sequences, much less…

Soft Condensed Matter · Physics 2025-05-15 Soumen De Karmakar , Thomas Speck

By combining analytical results and simulations of various coarse-grained models we investigate the minimal energy shape of DNA minicircles which are torsionally constrained by an imposed over or undertwist. We show that twist-bend…

Soft Condensed Matter · Physics 2019-08-08 Michele Caraglio , Enrico Skoruppa , Enrico Carlon

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2008-02-03 C. S. O'Hern , Randall D. Kamien , T. C. Lubensky , Philip Nelson

Resonant graphene dopants, such as hydrogen adatoms, experience long-range effective interaction mediated by conduction electrons. As a result of this interaction, when several adatoms are present in the sample, hopping of adatoms between…

Mesoscale and Nanoscale Physics · Physics 2016-03-23 Justin Talbot , Stephan LeBohec , Eugene Mishchenko

Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase. Using Monte Carlo…

Biomolecules · Quantitative Biology 2009-05-04 Hu Chen , Yanhui Liu , Zhen Zhou , Lin Hu , Zhong-Can Ou-Yang , Jie Yan

We advance our approach of analyzing the dynamics of interacting complex systems with the nonlinear dynamics of interacting nonlinear elements. We replace the widely used lattice-like connection topology of cellular neural networks (CNN) by…

Neurons and Cognition · Quantitative Biology 2016-10-10 Henning Dickten , Christian E. Elger , Klaus Lehnertz

The topological framework of circuit topology has recently been introduced to complement knot theory and to help in understanding the physics of molecular folding. Naturally evolved linear molecular chains, such as proteins and nucleic…

Geometric Topology · Mathematics 2021-09-07 Alireza Mashaghi , Roland van der Veen

A linear external perturbation is introduced in the action of the partition function of the random matrix model of RNA [G. Vernizzi, H. Orland and A. Zee, Phys. Rev. Lett. 94, 168103 (2005)]. It is seen that (i). the perturbation…

Biomolecules · Quantitative Biology 2009-11-20 I. Garg , N. Deo

Advances in DNA nanotechnology have stimulated the search for simple motifs that can be used to control the properties of DNA nanostructures. One such motif, which has been used extensively in structures such as polyhedral cages,…

Soft Condensed Matter · Physics 2015-06-10 John S. Schreck , Thomas E. Ouldridge , Flavio Romano , Ard A. Louis , Jonathan P. K. Doye