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We study the thermodynamic behavior of a simple off-lattice model for protein folding. The model is two-dimensional and has two different ``amino acids''. Using numerical simulations of all chains containing eight or ten monomers, we…

chem-ph · Physics 2009-10-28 Anders Irbäck , Frank Potthast

We investigate the folding and forced-unbinding transitions of adsorbed semiflexible polymer chains using theory and simulations. These processes describe biologically relevant phenomena that include adhesive interactions between proteins…

Soft Condensed Matter · Physics 2007-05-23 V. Barsegov , D. Thirumalai

Lattice model of directed self avoiding walk has been solved analytically to investigate adsorption desorption phase transition behaviour of a semiflexible sequential copolymer chain on a two dimensional impenetrable surface perpendicular…

Statistical Mechanics · Physics 2010-02-23 Pramod Kumar Mishra

We solve a two dimensional model for polymer chain folding in the presence of mechanical pulling force ($f$) exactly using equilibrium statistical mechanics. Using analytically derived expression for the partition function we determine the…

Statistical Mechanics · Physics 2015-06-12 Himadri S Samanta , D. Thirumalai

We analyze the freezing and collapse transition of a simple model for flexible polymer chains on simple cubic and face-centered cubic lattices by means of sophisticated chain-growth methods. In contrast to bond-fluctuation polymer models in…

Soft Condensed Matter · Physics 2009-02-16 Thomas Vogel , Michael Bachmann , Wolfhard Janke

We use the lattice model of directed walks to investigate the conformational as well as the adsorption properties of a semiflexible homopolymer chain immersed in a good solvent in two and three dimensions. To account for the stiffness in…

Statistical Mechanics · Physics 2009-11-07 P. K. Mishra , S. Kumar , Y. Singh

Using a simple three-dimensional lattice copolymer model and Monte Carlo dynamics, we study the collapse and folding of protein-like heteropolymers. The polymers are 27 monomers long and consist of two monomer types. Although these chains…

Condensed Matter · Physics 2009-10-22 Nicholas D. Socci , Jose' Nelson Onuchic

The folding transition of single, long semiflexible polymers was studied with special emphasis on the chain length effect using Monte Carlo simulations. While a relatively short chain (10-25 Kuhn segments) undergoes a large discrete…

Soft Condensed Matter · Physics 2008-05-06 Yuji Higuchi , Takahiro Sakaue , Kenichi Yoshikawa

We study numerically the tightness of prime flat knots in a model of self-attracting polymers with excluded volume. We find that these knots are localised in the high temperature swollen regime, but become delocalised in the low temperature…

Soft Condensed Matter · Physics 2009-11-07 E. Orlandini , A. L. Stella , C. Vanderzande

We present an application of Wertheim's Thermodynamic Perturbation Theory (TPT1) to a simple coarse grained model made of flexibly bonded Lennard-Jones monomers. We use both the Reference Hyper-Netted-Chain (RHNC) and Mean Spherical…

Statistical Mechanics · Physics 2016-08-15 L. González MacDowell , M. Mueller , C. Vega , K. Binder

There have been separate studies of the polymer collapse transition, where the collapse was induced by two different types of attraction. In each case, the configurations of the polymer were given by the same subset of random walks being…

Statistical Mechanics · Physics 2015-06-17 Andrea Bedini , Aleksander L Owczarek , Thomas Prellberg

We study a heteropolymer model with random contact interactions introduced some time ago as a simplified model for proteins. The model consists of self-avoiding walks on the simple cubic lattice, with contact interactions between nearest…

Soft Condensed Matter · Physics 2009-10-31 Ugo Bastolla , Peter Grassberger

An applied tension force changes the equilibrium conformations of a polymer chain tethered to a planar substrate and thus affects the adsorption transition as well as the coil-globule and crystallization transitions. Conversely, solvent…

Soft Condensed Matter · Physics 2015-06-22 Jutta Luettmer-Strathmann , Kurt Binder

We study the thermodynamic properties of a semiflexible polymer confined inside strips of widths L<=9 defined on a square lattice. The polymer is modeled as a self-avoiding walk and a short range interaction between the monomers and the…

Statistical Mechanics · Physics 2007-05-23 Jurgen F. Stilck

We study folding in 16-monomer heteropolymers on the square lattice. For a given sequence, thermodynamic properties and stability of the native state are unique. However, the kinetics of folding depends on the model of dynamics adopted for…

Statistical Mechanics · Physics 2009-10-31 Trinh Xuan Hoang , Marek Cieplak

By means of quantum Monte Carlo simulations implemented with a two-loop update scheme, the finite-temperature phase diagram of a three-body constrained attractive Bose lattice gas is investigated. The nature of the thermal phase transitions…

Quantum Gases · Physics 2011-03-24 Kwai-Kong Ng , Min-Fong Yang

Based on our previous paper [cond-mat/0507477], we establish a general model for the whip-toroid transitions of a semiflexible homopolymer chain using the path integral method and the O(3) nonlinear sigma model on a line segment with the…

Soft Condensed Matter · Physics 2007-05-23 Yukitaka Ishimoto , Norio Kikuchi

We present a detailed study of a model of close-packed dimers on the square lattice with an interaction between nearest-neighbor dimers. The interaction favors parallel alignment of dimers, resulting in a low-temperature crystalline phase.…

Statistical Mechanics · Physics 2009-11-11 Fabien Alet , Yacine Ikhlef , Jesper Lykke Jacobsen , Gregoire Misguich , Vincent Pasquier

It has been revealed by mean-field theories and computer simulations that the nature of the collapse transition of a polymer is influenced by its bending stiffness $\epsilon_{\rm b}$. In two dimensions, a recent analytical work demonstrated…

Soft Condensed Matter · Physics 2009-11-13 Jie Zhou , Zhong-Can Ou-Yang , Haijun Zhou

The nature of the globule-coil transition of surface-confined polymers has been an issue of debate. Here this 2D collapse transition is studied through a partially directed lattice model. In the general case of polymers with positive…

Soft Condensed Matter · Physics 2007-05-23 Haijun Zhou , Jie Zhou , Zhong-Can Ou-Yang , Sanjay Kumar