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Related papers: From Collapse to Freezing in Random Heteropolymers

200 papers

Planar/flat configurations of fixed-angle chains and trees are well studied in the context of polymer science, molecular biology, and puzzles. In this paper, we focus on a simple type of fixed-angle linkage: every edge has unit length…

Computational Geometry · Computer Science 2022-12-26 Erik D. Demaine , Hiro Ito , Jayson Lynch , Ryuhei Uehara

Natural protein sequences that self-assemble to form globular structures are compact with high packing densities in the folded states. It is known that proteins unfold upon addition of denaturants, adopting random coil structures. The…

Biomolecules · Quantitative Biology 2016-12-02 Himadri S. Samanta , Pavel I. Zhuravlev , Michael Hinczewski , Naoto Hori , Shaon Chakrabarti , D. Thirumalai

We propose and solve a simple model describing secondary structure formation in random hetero-polymers. It describes monomers with a combination of one-dimensional short-range interactions (representing steric forces and hydrogen bonds) and…

Disordered Systems and Neural Networks · Physics 2009-11-07 N. S. Skantzos , J. van Mourik , A. C. C. Coolen

We study a heteropolymer model with random contact interactions introduced some time ago as a simplified model for proteins. The model consists of self-avoiding walks on the simple cubic lattice, with contact interactions between nearest…

Soft Condensed Matter · Physics 2009-10-31 Ugo Bastolla , Peter Grassberger

A certain two-dimensional lattice model with nearest and next-nearest neighbor interactions is known to have a limit-periodic ground state. We show that during a slow quench from the high temperature, disordered phase, the ground state…

Statistical Mechanics · Physics 2012-01-30 Travis W. Byington , Joshua E. S. Socolar

My means of extensive Monte Carlo simulations the mean radius of gyration and the end-to-end distance are calculated for a single chain in a solvent over a broad range of volume fractions, pressures and temperatures. Our results indicate…

Statistical Mechanics · Physics 2007-05-23 C. Ortiz-Estrada , G. Luna-Barcenas , G. Ramirez-Santiago , I. C. Sanchez , J. F. Alvarado

We assume that the protein folding process follows two autonomous steps: the conformational search for the native, mainly ruled by the hydrophobic effect; and, the final adjustment stage, which eventually gives stability to the native. Our…

Biological Physics · Physics 2016-07-27 J. P. Dal Molin , A. Caliri

The some dynamic properties of a random heteropolymer in the condensed state are studied in the mode coupling approximation. In agreement with recent report a dynamic friction increasing is predicted for the random heteropolymer with…

Disordered Systems and Neural Networks · Physics 2007-05-23 E. Sh. Mamasakhlisov , V. F. Morozov

In our original article (Phys. Chem. Chem. Phys., 2012, 14, 60446053) a convergence problem resulted in an averaging error in computing the entropy from a set of Wang-Landau Monte-Carlo simulations. Here we report corrected results for the…

Soft Condensed Matter · Physics 2021-04-13 Bart Vorselaars , Štěpán Růžička , David Quigley , Michael P. Allen

De novo protein structure prediction from amino acid sequence is one of the most challenging problems in computational biology. As one of the extensively explored mathematical models for protein folding, Hydrophobic-Polar (HP) model enables…

Machine Learning · Computer Science 2018-12-06 Yanjun Li , Hengtong Kang , Ketian Ye , Shuyu Yin , Xiaolin Li

We investigate the dynamics of the collapse of a single copolymer chain, when the solvent quality is suddenly quenched from good to poor. We employ Brownian dynamics simulations of a bead-spring chain model and incorporate fluctuating…

Soft Condensed Matter · Physics 2020-07-03 Tri Thanh Pham , Burkhard Duenweg , J. Ravi Prakash

The thermodynamic behavior and structural properties of hydrophobic-polar (HP) lattice proteins interacting with attractive surfaces are studied by means of Wang-Landau sampling. Three benchmark HP sequences (48mer, 67mer, and 103mer) are…

Soft Condensed Matter · Physics 2013-01-16 Ying Wai Li , Thomas Wüst , David P. Landau

The nature of the globule-coil transition of surface-confined polymers has been an issue of debate. Here this 2D collapse transition is studied through a partially directed lattice model. In the general case of polymers with positive…

Soft Condensed Matter · Physics 2007-05-23 Haijun Zhou , Jie Zhou , Zhong-Can Ou-Yang , Sanjay Kumar

This report deals with phase transition in Bond Fluctuation Model (BFM) of a linear homo polymer on a two dimensional square lattice. Each monomer occupies a unit cell of four lattice sites. The condition that a lattice site can at best be…

Soft Condensed Matter · Physics 2012-04-16 Hima Bindu Kolli , K. P. N. Murthy

We investigate a lattice model of polymers where the nearest-neighbour monomer-monomer interaction strengths differ according to whether the local configurations have so-called ``hydrogen-like'' formations or not. If the interaction…

Soft Condensed Matter · Physics 2009-11-13 J Krawczyk , A L Owczarek , T Prellberg

The density crossover scaling of various thermodynamic properties of solutions and melts of self-avoiding and highly flexible polymer chains without chain intersections confined to strictly two dimensions is investigated by means of…

Soft Condensed Matter · Physics 2012-09-03 N. Schulmann , H. Meyer , P. Polińska , J. Baschnagel , J. P. Wittmer

Applying multicanonical simulations we investigated folding properties of off-lattice heteropolymers employing a mesoscopic hydrophobic-polar model. We study for various sequences folding channels in the free-energy landscape by comparing…

Soft Condensed Matter · Physics 2009-02-17 Stefan Schnabel , Michael Bachmann , Wolfhard Janke

We study the scaling of the entanglement entropy in different classes of one-dimensional fermionic quasiperiodic systems with and without pairing, focusing on multifractal critical points/phases. We find that the entanglement entropy scales…

Strongly Correlated Electrons · Physics 2024-03-12 Miguel Gonçalves

We investigate the dynamics and the pathways of the collapse of a single, semiflexible polymer in a poor solvent via 3-D Brownian Dynamics simulations. Earlier work indicates that the condensation of semiflexible polymers generically…

Soft Condensed Matter · Physics 2009-11-10 Alberto Montesi , Matteo Pasquali , F. C. MacKintosh

Recently, it has been demonstrated [Magee et al., Phys. Rev. Lett. 96, 207802 (2006)] that isolated, square-well homopolymers can spontaneously break chiral symmetry and freeze into helical structures at sufficiently low temperatures. This…

Soft Condensed Matter · Physics 2013-09-30 M. N. Bannerman , J. E. Magee , L. Lue