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Related papers: Random Hydrophilic-Hydrophobic Copolymers

200 papers

In suitable environments, proteins, nucleic acids and certain synthetic polymers fold into unique conformations. This work shows that it is possible to construct lattice models of foldable heteropolymers by expressing the energy only in…

Soft Condensed Matter · Physics 2009-10-31 Michele Vendruscolo

Lattice model of directed self avoiding walk has been solved analytically to investigate adsorption desorption phase transition behaviour of a semiflexible sequential copolymer chain on a two dimensional impenetrable surface perpendicular…

Statistical Mechanics · Physics 2010-02-23 Pramod Kumar Mishra

The mechanism of the collapse of the superhydrophobic state is elucidated for submerged nanoscale textures forming a three-dimensional interconnected vapor domain. This key issue for the design of nanotextures poses significant simulation…

Soft Condensed Matter · Physics 2017-03-31 Matteo Amabili , Alberto Giacomello , Simone Meloni , Carlo Massimo Casciola

In recent experiments, small, thick-walled vesicles with a narrow size distribution were formed from copolymers where the degree of polymerisation of the hydrophobic block, N_B, was significantly greater than that of the hydrophilic block,…

Soft Condensed Matter · Physics 2017-09-12 M. J. Greenall

We study at- and out-of-equilibrium dynamics of a single homopolymer chain at low temperature using molecular dynamics simulations. The main quantities of interest are the average root mean square displacement of the monomers below the…

Soft Condensed Matter · Physics 2009-11-07 Nikolay V. Dokholyan , Estelle Pitard , Sergey V. Buldyrev , H. Eugene Stanley

In this paper we consider a two-dimensional copolymer consisting of a random concatenation of hydrophobic and hydrophilic monomers near a linear interface separating oil and water acting as solvents. The configurations of the copolymer are…

Probability · Mathematics 2012-02-21 E. Bolthausen , F. den Hollander , A. A. Opoku

Synthetic copolymers and biopolymers, such as polypeptides and double-stranded DNA, often exhibit strong variations in bending stiffness along their contour, which can significantly impact conformational behavior at larger scales. To…

Soft Condensed Matter · Physics 2025-11-04 Yannick Witzky , Friederike Schmid , Arash Nikoubashman

We study the kinetics of assembly of two plates of varying hydrophobicity, including cases where drying occurs and water strongly solvates the plate surfaces. The potential of mean force and molecular-scale hydrodynamics are computed from…

Soft Condensed Matter · Physics 2012-08-31 Jingyuan Li , Joseph A. Morrone , B. J. Berne

In order to understand the nuclei which develop during the course of protein folding and unfolding, we examine phase segregation of a single heteropolymer chain which occurs in equilibrium. These segregated conformations are characterized…

Disordered Systems and Neural Networks · Physics 2009-10-31 Rose Du , Alexander Yu. Grosberg , Toyoichi Tanaka

To study the localization of random heteropolymers at an interface separating two selective solvents within the model of Garel, Huse, Leibler and Orland, Europhys. Lett. {\bf 8} 9 (1989), we propose an approach based on a disorder-dependent…

Condensed Matter · Physics 2015-06-25 Cecile Monthus

The precise arrangement of different chemical moieties in a polymer determines its thermophysical properties. How the sequence of moieties impacts the properties of a polymer is an outstanding problem in polymer science. Herein, we address…

Soft Condensed Matter · Physics 2025-08-26 Sandeep Parma , R. Nagaranajan , Tarak K Patra

Clean oxide surfaces are generally hydrophilic. Water molecules anchor at undercoordinated surface metal atoms that act as Lewis-acid sites, and they are stabilized by H bonds to undercoordinated surface oxygens. The large unit cell of…

Hydrophobicity is thought to be one of the primary forces driving the folding of proteins. On average, hydrophobic residues occur preferentially in the core, whereas polar residues tends to occur at the surface of a folded protein. By…

Biomolecules · Quantitative Biology 2007-05-23 Susanne Moelbert , Eldon Emberly , Chao Tang

Based on large-scale Monte Carlo simulations on lattice the energy probability distribution functions are investigated for a large set of primary sequences in distinct models of copolymers at low temperatures below transitions to compacted…

Soft Condensed Matter · Physics 2007-05-23 Edward G. Timoshenko , Yuri A. Kuznetsov , Roman N. Basovsky

The phase structure of a homopolymer chain is investigated in terms of a universal theoretical model, designed to describe the infrared limit of slow spatial variations. The effects of chirality are studied and compared with the influence…

Soft Condensed Matter · Physics 2015-12-25 A. Sinelnikova , A. J. Niemi , M. Ulybyshev

Recent studies of the hydration of micro- and nanoscale solutes have demonstrated a strong {\it coupling} between hydrophobic, dispersion and electrostatic contributions, a fact not accounted for in current implicit solvent models. We…

Chemical Physics · Physics 2009-11-11 J. Dzubiella , J. M. J. Swanson , J. A. McCammon

Interfaces are a most common motif in complex systems. To understand how the presence of interfaces affect hydrophobic phenomena, we use molecular simulations and theory to study hydration of solutes at interfaces. The solutes range in size…

Soft Condensed Matter · Physics 2014-09-05 Amish J. Patel , Patrick Varilly , Sumanth N. Jamadagni , Hari Acharya , Shekhar Garde , David Chandler

In recent experiments involving PNIPAM copolymers it has been observed that stable spherical nanoparticles are being formed by association of several chains in poor aqueous solution instead of aggregation. This type of mesoscopic structures…

Soft Condensed Matter · Physics 2007-05-23 E. G. Timoshenko , R. Basovsky , Yu. A. Kuznetsov

We examine phase separation in aqueous mixtures due to preferential solvation with a low-density solute (hydrophilic ions or hydrophobic particles). For hydrophilic ions, preferential solvation can stabilize water domains enriched with…

Soft Condensed Matter · Physics 2015-05-20 Ryuichi Okamoto , Akira Onuki

We study the Brownian dynamics of flexible and semiflexible polymer chains densely grafted on a flat substrate, upon rapid quenching of the system when the quality of solvent becomes poor and chains attempt collapse into a globular state.…

Soft Condensed Matter · Physics 2015-08-19 Anna Lappala , Saahil Mendiratta , Eugene M. Terentjev