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Related papers: Heteropolymer translocation through nanopores

200 papers

We consider elongated cylindrical particles, modeling e.g. DNA fragments or nano-rods, while translocating under the action of an externally applied voltage through a solid state nanopore. Particular emphasis is put on the concomitant…

Soft Condensed Matter · Physics 2013-07-15 Sebastian Getfert , Thomas Töws , Peter Reimann

We consider a polymer of length $N$ translocating through a narrow pore in the absence of external fields. Characterization of its purportedly anomalous dynamics has so far remained incomplete. We show that the polymer dynamics is anomalous…

Soft Condensed Matter · Physics 2007-10-08 Debabrata Panja , Gerard T. Barkema , Robin C. Ball

Using a simple three-dimensional lattice copolymer model and Monte Carlo dynamics, we study the collapse and folding of protein-like heteropolymers. The polymers are 27 monomers long and consist of two monomer types. Although these chains…

Condensed Matter · Physics 2009-10-22 Nicholas D. Socci , Jose' Nelson Onuchic

Here using LAMMPS molecular dynamics (MD) software, we simulate polymer translocation in 2 dimensions. We do the simulations for weak and moderate forces and for different pore diameters. Our results show that in both non-equilibrium and…

Computational Physics · Physics 2018-04-26 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

Polymer-coated pores play a crucial role in nucleo-cytoplasmic transport and in a number of biomimetic and nanotechnological applications. Here we present Monte Carlo and Density Functional Theory approaches to identify different collective…

Soft Condensed Matter · Physics 2015-05-30 Dino Osmanovic , Joe Bailey , Anthony H. Harker , Ariberto Fassati , Bart W. Hoogenboom , Ian J. Ford

We investigate the influence of polymer-pore interactions on the translocation dynamics using Langevin dynamics simulations. An attractive interaction can greatly improve translocation probability. At the same time, it also increases…

Soft Condensed Matter · Physics 2007-10-01 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying , Aniket Bhattacharya

Polymer nanofibers with high thermal conductivities and outstanding thermal stabilities are highly desirable in heat transfer-critical applications such as thermal management, heat exchangers and energy storage. In this work, we unlock the…

Chemical Physics · Physics 2014-09-12 Teng Zhang , Xufei Wu , Tengfei Luo

We investigate the crystallization of a single, flexible homopolymer chain using transition path sampling (TPS). The chain consists of N identical spherical monomers evolved according to Langevin dynamics. While neighboring monomers are…

Soft Condensed Matter · Physics 2016-08-17 Christian Leitold , Christoph Dellago

We study the diffusion of a linear polymer in the presence of permeable membranes without excluded volume interactions, using scaling theory and Monte Carlo simulations. We find that the average time it takes for a chain with polymerization…

Condensed Matter · Physics 2016-08-31 Hyoungsoo Yoon , J. M. Deutsch

We employ a multiscale approach to model the translocation of biopolymers through nanometer size pores. Our computational scheme combines microscopic Molecular Dynamics (MD) with a mesoscopic Lattice Boltzmann (LB) method for the solvent…

Computational Physics · Physics 2008-02-27 Maria Fyta , Jayanta Sircar , Efthimios Kaxiras , Simone Melchionna , Massimo Bernaschi , Sauro Succi

We construct a new statistical physical model of polymer translocation through a pore in a membrane treated as the diffusion process across a free energy barrier. We determine the translocation time in terms of chain flexibility yielding an…

Soft Condensed Matter · Physics 2015-06-25 W. Sung , P. J. Park

Using continuous time Monte-Carlo method we simulated the translocation of a polynucleotide chain driven through a nanopore by an electric field. We have used two models of driven diffusion due to the electric field. The chain may have…

Soft Condensed Matter · Physics 2009-11-11 Pui-Man Lam , Fei Liu , Zhong-can OuYang

We investigate the driven polymer translocation through a nanometer-scale pore in the presence and absence of hydrodynamics both in good and bad solvent. We present our results on tension propagating along the polymer segment on the…

Biological Physics · Physics 2016-09-21 Jaakko E. Moisio , Joonas Piili , Riku P. Linna

Polymer translocation through a nanometer-scale pore assisted by chaperones binding to the polymer is a process encountered in vivo for proteins. Studying the relevant models by computer simulations is computationally demanding.…

Biological Physics · Physics 2017-12-18 P. M. Suhonen , R. P. Linna

Molecular dynamics simulations are used to study the spreading of binary polymer nanodroplets in a cylindrical geometry. The polymers, described by the bead-spring model, spread on a flat surface with a surface-coupled Langevin thermostat…

Soft Condensed Matter · Physics 2007-05-23 David R. Heine , Gary S. Grest , Edmund B. Webb

Most of the theoretical models describing the translocation of a polymer chain through a nanopore use the hypothesis that the polymer is always relaxed during the complete process. In other words, models generally assume that the…

Biomolecules · Quantitative Biology 2009-11-13 Michel G. Gauthier , Gary W. Slater

When applying a voltage bias across a thin nanopore, localized Joule heating can lead to single bubble nucleation, offering a unique platform for studying nanoscale bubble behavior, which is still poorly understood. Accordingly, we…

In this work we study the noise induced effects on the dynamics of short polymers crossing a potential barrier, in the presence of a metastable state. An improved version of the Rouse model for a flexible polymer has been adopted to mimic…

Statistical Mechanics · Physics 2009-11-13 N. Pizzolato , A. Fiasconaro , B. Spagnolo

Sensitive sequencing of biopolymers by nanopore-based translocation techniques requires extension of the time spent by the molecule in the pore. We develop an electrostatic theory of polymer translocation to show that the translocation time…

Soft Condensed Matter · Physics 2018-11-12 Sahin Buyukdagli , Jalal Sarabadani , Tapio Ala-Nissila

The mechanism of thermal conductivity in amorphous polymers, especially polymer fibers, is unclear in comparison with that in inorganic materials. Here, we report the observation of across over of heat conduction behavior from three…

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