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Mechanobiology is gaining more and more traction as the fundamental role of physical forces in biological function becomes clearer. Forces at the microscale are often measured indirectly using inverse problems such as Traction Force…

Biological Physics · Physics 2025-03-21 Aleix Boquet-Pujadas

We present a method to generate realistic, three-dimensional networks of crosslinked semiflexible polymers. The free energy of these networks is obtained from the force-extension characteristics of the individual polymers and their…

Soft Condensed Matter · Physics 2009-11-13 E. M. Huisman , C. Storm , G. T. Barkema

Utilizing discrete phase distribution to fit continuous phase distribution has been a primary routine for designing metasurfaces. In the existing method, the validation of the discrete designs is guaranteed only by using the sub-wavelength…

Optics · Physics 2017-11-09 Wenwei Liu , Zhancheng Li , Hua Cheng , Shuqi Chen , Jianguo Tian

Multiphase field models have emerged as an important computational tool for understanding biological tissue while resolving single-cell properties. While they have successfully reproduced many experimentally observed behaviors of living…

Soft Condensed Matter · Physics 2025-02-13 Michael Chiang , Austin Hopkins , Benjamin Loewe , Davide Marenduzzo , M. Cristina Marchetti

This paper is committed to investigate an extension of the classical adaptive biasing force method, which is used to compute the free energy related to the Boltzmann-Gibbs measure and a reaction coordinate function. The issue of this…

Probability · Mathematics 2017-11-08 Houssam AlRachid , Tony Lelievre

In many areas of imaging science, it is difficult to measure the phase of linear measurements. As such, one often wishes to reconstruct a signal from intensity measurements, that is, perform phase retrieval. In this paper, we provide a…

Information Theory · Computer Science 2013-09-13 Boris Alexeev , Afonso S. Bandeira , Matthew Fickus , Dustin G. Mixon

We develop a projected Wasserstein distance for the two-sample test, a fundamental problem in statistics and machine learning: given two sets of samples, to determine whether they are from the same distribution. In particular, we aim to…

Machine Learning · Statistics 2024-04-01 Jie Wang , Rui Gao , Yao Xie

An atomic force microscope (AFM) is capable of producing ultra-high resolution measurements of nanoscopic objects and forces. It is an indispensable tool for various scientific disciplines such as molecular engineering, solid-state physics,…

Applications · Statistics 2017-06-28 Bryan Yates , Aleksander Labuda , Martin Lysy

The choice of sample size in the context of co-primary endpoints for a randomised trial is discussed. Current guidance can leave endpoints with unequal marginal power. A method is provided to achieve equal marginal power by using the…

Methodology · Statistics 2026-02-23 Simon Bond

We investigate membrane-mediated interactions between transmembrane proteins using coarse-grained models. We compare the effective potential of mean force (PMF) between two proteins, which are always aligned parallel to the z-axis of the…

Biological Physics · Physics 2012-04-11 Joerg Neder , Beate West , Peter Nielaba , Friederike Schmid

We investigate solution methods for large-scale inverse problems governed by partial differential equations (PDEs) via Bayesian inference. The Bayesian framework provides a statistical setting to infer uncertain parameters from noisy…

Applications · Statistics 2023-02-08 Mina Karimi , Mehrdad Massoudi , Kaushik Dayal , Matteo Pozzi

A novel embedded atom method (EAM) potential for the Xi-phases of Al-Pd-Mn has been determined with the force-matching method. Different combinations of analytic functions were tested for the pair and transfer part. The best results are…

Materials Science · Physics 2012-02-09 Daniel Schopf , Peter Brommer , Benjamin Frigan , Hans-Rainer Trebin

We study Monte Carlo calculations of the effective potential for a scalar field theory using three techniques. One of these is a new method proposed and tested for the first time. In each case we extract the renormalised quantities of the…

High Energy Physics - Lattice · Physics 2010-03-04 A. Ardekani , A. G. Williams

By breaking both the axial and the spatial reflection symmetries, we develop multidimensionally constrained relativistic mean field (MDC-RMF) models. The nuclear shape is assumed to be invariant under the reversion of $x$ and $y$ axes,…

Nuclear Theory · Physics 2014-02-05 Bing-Nan Lu , Jie Zhao , En-Guang Zhao , Shan-Gui Zhou

In NMR spectroscopy, undersampling in the indirect dimensions causes reconstruction artifacts whose size can be bounded using the so-called {\it coherence}. In experiments with multiple indirect dimensions, new undersampling approaches were…

Applications · Statistics 2017-02-08 Hatef Monajemi , David L. Donoho , Jeffrey C. Hoch , Adam D. Schuyler

We perform a systematic application of the hybrid particle-field molecular dynamics technique [Milano et al, J. Chem. Phys. 2009, 130, 214106] to study interfacial properties and potential of mean force (PMF) for separating nanoparticles…

While multislice electron ptychography can provide thermal-vibration limited resolution and 3D information, it relies on the proper selection of many intertwined experimental and computational parameters. Here, we outline a theoretical…

Materials Science · Physics 2023-11-28 Colin Gilgenbach , Xi Chen , James M. LeBeau

Ligand coated nanoparticles are complex objects consisting of a metallic or semiconductor core with organic ligands grafted on their surface. These organic ligands provide stability to a nanoparticle suspension. In solutions, the effective…

Soft Condensed Matter · Physics 2022-03-01 Dinesh Chintha , Shivanand Kumar Veesam , Emanuele Boattini , Laura Filion , Sudeep N Punnathanam

To conduct Bayesian inference with large data sets, it is often convenient or necessary to distribute the data across multiple machines. We consider a likelihood function expressed as a product of terms, each associated with a subset of the…

Computation · Statistics 2020-04-09 Lewis J. Rendell , Adam M. Johansen , Anthony Lee , Nick Whiteley

We study the elastic properties of a single A/B copolymer chain with a specific sequence. We predict a rich structure in the force extension relations which can be addressed to the sequence. The variational method is introduced to probe…

Soft Condensed Matter · Physics 2009-11-07 Namkyung Lee , Thomas A. Vilgis